Drug discovery for psychiatric disorders
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Format: | Elektronisch E-Book |
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Sprache: | English |
Veröffentlicht: |
Cambridge
Royal Society of Chemistry
2012
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Schriftenreihe: | RSC drug discovery series
no. 28 |
Schlagworte: | |
Online-Zugang: | DE-1046 DE-1047 Volltext |
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500 | |a The discovery and development of effective medicines for the treatment of psychiatric disorders such as schizophrenia and depression has been heralded as one of the great medical achievements of the past century. Indeed, the profound impact of these medicines on our understanding of the pathophysiology underlying these diseases, the treatment of psychiatric patients and even our social perception of mental illnesses cannot be underestimated. However, there is still an urgent medical need for even more effective, safe and well-tolerated treatments. For example, currently available treatments for schizophrenia address mainly the positive symptoms and largely neglect the negative symptoms and cognitive disfunction which greatly impact overall morbidity. Similarly, whilst the current first line antidepressants show significantly improved side effect profiles compared to the first generation therapies, there still up to 40% of patients who are treatment resistant, and even in the patient population which responds well, the onset of action is slow at typically 2-3 weeks. The aim of this book is to provide the first point of call for those involved or just interested in this rapidly expanding and increasingly fragmented field of research and drug discovery. The editors will combine their wide ranging experience and extensive network of contacts with leading scientists and opinion leaders in this field to provide an authoritative reference text covering the evolution, major advances, challenges and future directions in drug discovery and medicinal chemistry for major psychiatric disorders, such as schizophrenia, depression, anxiety, ADHD, bipolar disorder, addiction and autism | ||
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dewey-search | 615.78 |
dewey-sort | 3615.78 |
dewey-tens | 610 - Medicine and health |
discipline | Medizin |
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spelling | Drug discovery for psychiatric disorders edited by Zoran Rankovic ... [et al.] Cambridge Royal Society of Chemistry 2012 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier RSC drug discovery series no. 28 The discovery and development of effective medicines for the treatment of psychiatric disorders such as schizophrenia and depression has been heralded as one of the great medical achievements of the past century. Indeed, the profound impact of these medicines on our understanding of the pathophysiology underlying these diseases, the treatment of psychiatric patients and even our social perception of mental illnesses cannot be underestimated. However, there is still an urgent medical need for even more effective, safe and well-tolerated treatments. For example, currently available treatments for schizophrenia address mainly the positive symptoms and largely neglect the negative symptoms and cognitive disfunction which greatly impact overall morbidity. Similarly, whilst the current first line antidepressants show significantly improved side effect profiles compared to the first generation therapies, there still up to 40% of patients who are treatment resistant, and even in the patient population which responds well, the onset of action is slow at typically 2-3 weeks. The aim of this book is to provide the first point of call for those involved or just interested in this rapidly expanding and increasingly fragmented field of research and drug discovery. The editors will combine their wide ranging experience and extensive network of contacts with leading scientists and opinion leaders in this field to provide an authoritative reference text covering the evolution, major advances, challenges and future directions in drug discovery and medicinal chemistry for major psychiatric disorders, such as schizophrenia, depression, anxiety, ADHD, bipolar disorder, addiction and autism MEDICAL / Pain Medicine bisacsh MEDICAL / Psychiatry / Psychopharmacology bisacsh Psychotropic Drugs Psychopharmacology Psychopharmacology fast Psychotropic drugs fast Medizin Psychotropic drugs Ranković, Zoran Sonstige oth http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=519376 Aggregator Volltext |
spellingShingle | Drug discovery for psychiatric disorders MEDICAL / Pain Medicine bisacsh MEDICAL / Psychiatry / Psychopharmacology bisacsh Psychotropic Drugs Psychopharmacology Psychopharmacology fast Psychotropic drugs fast Medizin Psychotropic drugs |
title | Drug discovery for psychiatric disorders |
title_auth | Drug discovery for psychiatric disorders |
title_exact_search | Drug discovery for psychiatric disorders |
title_full | Drug discovery for psychiatric disorders edited by Zoran Rankovic ... [et al.] |
title_fullStr | Drug discovery for psychiatric disorders edited by Zoran Rankovic ... [et al.] |
title_full_unstemmed | Drug discovery for psychiatric disorders edited by Zoran Rankovic ... [et al.] |
title_short | Drug discovery for psychiatric disorders |
title_sort | drug discovery for psychiatric disorders |
topic | MEDICAL / Pain Medicine bisacsh MEDICAL / Psychiatry / Psychopharmacology bisacsh Psychotropic Drugs Psychopharmacology Psychopharmacology fast Psychotropic drugs fast Medizin Psychotropic drugs |
topic_facet | MEDICAL / Pain Medicine MEDICAL / Psychiatry / Psychopharmacology Psychotropic Drugs Psychopharmacology Psychotropic drugs Medizin |
url | http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=519376 |
work_keys_str_mv | AT rankoviczoran drugdiscoveryforpsychiatricdisorders |