Acute toxicology testing
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
San Diego
Academic Press
c1998
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| Ausgabe: | 2nd ed |
| Schlagworte: | |
| Online-Zugang: | DE-1046 DE-1047 Volltext |
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| Beschreibung: | Errata slip inserted. - Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002 Acute toxicology testing provides the first line of defense against potentially dangerous chemicals. This book is a complete and practical guide to conducting and interpreting all regulatory required and commonly used acute toxicity tests. It presents detailed protocols for all of the common test designs and reviews their development and objectives. Acute Toxicology Testing, Second Edition will interest not only workers in the pharmaceutical industry, but also researchers and students in toxicology and public health. Key Features * Over 100 tables summarizing and interpreting results * Complete coverage of all major test designs and their limitations and advantages * Current status of alternative test designs and models Introduction. Acute Toxicology Program: Study Design and Development. Tests for Dermal Irritation and Corrosion. Ocular Irritation Testing. Dermal Sensitization. Photosensitization/Phototoxicity. Lethality Testing. Safety Considerations for the Administration of Agents By the Parenteral Routes. Acute Systemic Toxicity Tests. Routes, Formulations, And Vehicles. Considerations Specific to Animal Test Models. Statistical Analysis for Acute Toxicology. Acute Inhalation. Problems and Issues. Appendices. Subject Index Includes bibliographical references and index |
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| Beschreibung: | 1 Online-Ressource (xvii, 534 p.) |
| ISBN: | 008052592X 0122722507 9780080525921 9780122722509 |