Cell-penetrating peptides methods and protocols

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Weitere Verfasser: Langel, Ülo (HerausgeberIn)
Format: Buch
Sprache:English
Veröffentlicht: New York [u.a.] Humana Press 2015
Ausgabe:2. ed.
Schriftenreihe:Methods in molecular biology 1324
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Datensatz im Suchindex

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adam_text Contents Preface......................................................................... v Contributors................................................................. xiii Part I Introduction 1 Classes of Cell-Penetrating Peptides........................................ 3 Margus Pooga and Ülo Langel 2 Penetratin Story: An Overview.............................................. 29 Edmond Dupont, Alain Prochiantz, and Alain Joliot 3 Prediction of Cell-Penetrating Peptides ................................... 39 Maffias Hallbrink and Mati Karelson 4 Computer-Aided Virtual Screening and Designing of Cell-Penetrating Peptides.............................................. 59 Ankuv Gautam, Kumar deep Chaudhary, Kabul Kumar, and Gajendra Pal Singh Raghava Part II Methods to Test Mechanisms of Cell-Penetrating Peptides 5 Investigating Membrane Interactions and Structures of CPPs............... 73 Fatemeh Madani and Astrid Graslund 6 Determining the Effects of Membrane-Interacting Peptides on Membrane Integrity................................................... 89 William C. Wimley 7 Study of CPP Mechanisms by Mass Spectrometry............................. 107 Sandrine Sagan, Cherine Bechara, and Fabienne Burlina 8 Methods to Study the Role of the Glycocalyx in the Uptake of Cell-Penetrating Peptides............................................ 123 Samuel Schmidt, Kike Wallbrechev, Toin H. van Kuppevelt, and Roland Brock 9 Toxicity, Immunogenicity, Uptake, and Kinetics Methods for CPPs.......... 133 Julia Uusna, Kent Langel, and Ulo Langel 10 Unraveling the Mechanisms of Peptide-Mediated Delivery of Nucleic Acids Using Electron Microscopy.............................. 149 Helerin Margus, Carmen Juks, and Margus Pooga 11 SCARA Involvement in the Uptake of Nanoparticles Formed by Cell-Penetrating Peptides............................................ 163 Henrik Helmfors, Staffan Lindberg, and Ulo Langel ix 177 191 205 223 247 261 279 303 317 331 339 349 357 369 387 397 x Contents Part III Applications of Cpps In Vitro and In Vivo 12 Protein Mimicry and the Design of Bioactive Cell-Penetrating Peptides John Howl and Sarah Jones 13 Pepducins and Other Lipidated Peptides as Mechanistic Probes and Therapeutics.................................................. Ping Zhang, Lidija Covic, and Athan Kuliopulos 14 Identification and Characterization of Homing Peptides Using In Vivo Peptide Phage Display..................................... Maija Hyvonen and Pirjo Laakkonen 15 The Antimicrobial and Antiviral Applications of Cell-Penetrating Peptides...................................... Kalle Pdrn, Elo Eriste, and Ulo Langel 16 Visualizing Actin Architectures in Cells Incubated with Cell-Penetrating Peptides.................................... Lin He, Peter D. Watson, and Arwyn T. Jones 17 Cell-Penetrating Peptides as Carriers for Transepithelial Drug Delivery In Vitro............................................ Stine Panholt, Mie Kristensen, and Hanne March Nielsen 18 A Pathway Toward Tumor Cell-Selective CPPs?....................... Isabel D. Alves, Manon Carre, and Solange Lavielle 19 PepFects and NickFects for the Intracellular Delivery of Nucleic Acids.................................................. Piret Arukuusk, Ly Pdrnaste, Mattias Hdllbrink, and Ulo Langel 20 In Vitro Assays to Assess Exon Slopping in Duchenne Muscular Dystrophy................................................ Prisca Boisguerin, Liz O’Donovan, Michael J. Gait, and Bernard Lebleu 21 Applications of ApoB LDLR-Binding Domain Approach for the Development of CNS-Penetrating Peptides for Alzheimer’s Disease . . Eliezer Masliah and Brian Spencer 22 CPP-Based Delivery System for In Vivo Gene Delivery............... Kaido Kurrikojf, Kadi-Liis Veiman, and Ulo Langel 23 Application of CPPs for Brain Delivery............................ Artita Srimanee, Jakob Begberg, and Ulo Langel 24 Intracellular Delivery of Nanoparticles with Cell Penetrating Peptides . Giuseppina Salzano and Vladimir P Torchilin 25 Multifunctional Oligoaminoamides for the Receptor-Specific Delivery of Therapeutic RNA....................................... Judith Weber, Ulrich Lachelt, and Ernst Wagner 26 Cell Penetrating Peptides for Chemical Biological Studies......... Ikuhiko Nakase, Toshihide Takeuchi, and Shiroh Futaki 27 Experiences with CPP-Based Self Assembling Peptide Systems for Topical Delivery of Botulinum Toxin........................... Jane Lee, Phil Kennedy, and Jacob M. Waugh Contents xi 28 Applications of CPPs in Genome Modulation of Plants......................... 417 Alicja Ziemienowicz, Jordan Pepper and François Eudes 29 DNA Transfer into Animal Cells Using Stearylated CPP Based Transfection Reagent....................................................... 435 Kristiina Karvo Tiiu Mannik, Andres Mdnniky and Mart JJstav 30 Live Cell Genomics: Cell-Specific Transcriptome Capture in Live Tissues and Cells..................................................... 447 Thomas J. Bell and James Eberwine 31 Live Cell Genomics: RNA Exon-Specific RNA-Binding Protein Isolation .... 457 Thomas J. Bell and James Eberwine Erratum to........................................................................ El index............................................................................ 469
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Springer protocols
spellingShingle Cell-penetrating peptides methods and protocols
Methods in molecular biology
Peptide (DE-588)4045125-2 gnd
Membrantransport (DE-588)4038575-9 gnd
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title Cell-penetrating peptides methods and protocols
title_auth Cell-penetrating peptides methods and protocols
title_exact_search Cell-penetrating peptides methods and protocols
title_full Cell-penetrating peptides methods and protocols ed. by Ülo Langel
title_fullStr Cell-penetrating peptides methods and protocols ed. by Ülo Langel
title_full_unstemmed Cell-penetrating peptides methods and protocols ed. by Ülo Langel
title_short Cell-penetrating peptides
title_sort cell penetrating peptides methods and protocols
title_sub methods and protocols
topic Peptide (DE-588)4045125-2 gnd
Membrantransport (DE-588)4038575-9 gnd
topic_facet Peptide
Membrantransport
Aufsatzsammlung
url http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028046160&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
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