The minipig in biomedical research
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| Format: | Buch |
| Sprache: | English |
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Boca Raton [u.a.]
CRC Press/Taylor & Francis
2012
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| 008 | 150519s2012 xxua||| |||| 00||| eng d | ||
| 010 | |a 2011039677 | ||
| 020 | |a 9781439811184 |c hardback : alk. paper |9 978-1-439-81118-4 | ||
| 020 | |a 1439811180 |c hardback : alk. paper |9 1-439-81118-0 | ||
| 035 | |a (OCoLC)838842264 | ||
| 035 | |a (DE-599)BVBBV042567447 | ||
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| 050 | 0 | |a SF407.S97 | |
| 082 | 0 | |a 636.0885 | |
| 245 | 1 | 0 | |a The minipig in biomedical research |c edited by Peter A. McAnulty ... |
| 264 | 1 | |a Boca Raton [u.a.] |b CRC Press/Taylor & Francis |c 2012 | |
| 300 | |a XVII, 643 S., [46] S. |b Ill. |c 29 cm | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 500 | |a "A CRC title." | ||
| 500 | |a Includes bibliographical references and index | ||
| 650 | 7 | |a miniature pigs |2 cabt | |
| 650 | 7 | |a animal experiments |2 cabt | |
| 650 | 7 | |a animal models |2 cabt | |
| 650 | 4 | |a Animals, Laboratory | |
| 650 | 4 | |a Swine, Miniature | |
| 650 | 4 | |a Animal Welfare | |
| 650 | 4 | |a Biomedical Research |x methods | |
| 650 | 4 | |a Disease Models, Animal | |
| 700 | 1 | |a McAnulty, Peter A. |0 (DE-588)1019645105 |4 edt | |
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| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-028001065 | |
Datensatz im Suchindex
| _version_ | 1819671667755974656 |
|---|---|
| adam_text | Titel: The minipig in biomedical research
Autor: McAnulty, Peter A.
Jahr: 2012
Contents
Preface................................................................................................................................................................xi
Editors..............................................................................................................................................................xiii
Contributors......................................................................................................................................................xv
Section I
Origin and Management of the Minipig
Chapter 1
History and Development of Miniature, Micro- and Minipigs...............................................................................................3
Friederike Köhn
Chapter 2
Husbandry and Management..................................................................................................................................................17
Roberta Scipioni Ball
Chapter 3
Diseases of Minipigs..............................................................................................................................................................37
Nanna Grand
Chapter 4
International Transportation of Minipigs..............................................................................................................................69
Finn Raaschou-Nielsen
Section II
Welfare and Experimental Usage of the Minipig
Chapter 5
Ethical Issues in the Use of Minipigs in Animal Research...................................................................................................77
David Morton
Chapter 6
Animal Welfare Issues...........................................................................................................................................................85
Kathy E. Laber, Alison C. Smith and M. Michael Swindle
Chapter 7
Stress in Experiments: Stress Issues in Porcine Research.....................................................................................................93
Larry Dale Brown and Laust Peter Gade
Chapter 8
Dosing Methods....................................................................................................................................................................117
Peter Clausing
vi CONTENTS
Chapter 9
In-Life Clinical Observations..............................................................................................................................................127
David M. Cameron
Section III
Pharmacology and ADME Studies in the Minipig
Chapter 10
Minipigs in Absorption, Distribution, Metabolism, and Excretion (ADME) Studies..........................................................143
Cornelia Preuße and Mette Tingleff Skaanild
Chapter 11
The Minipig in Safety Pharmacology...................................................................................................................................159
Stephane Milano
Section IV
Safety Assessment in the Minipig-Principal Body Systems
Chapter 12
Dermal Toxicity Studies: Skin Architecture, Metabolism, Penetration and Toxicological
and Pharmacological Methods..............................................................................................................................................185
Andrew Makin, Jens Thing Mortensen and William J. Brock
Chapter 13
Gastrointestinal Tract............................................................................................................................................................211
Chris Van Ginneken
Chapter 14
Heart and Cardiotoxicity.....................................................................................................................................................237
James R. Turk
Chapter 15
Central and Peripheral Nervous Systems............................................................................................................................243
Allan Dahl Rasmussen and Karen Malene Wegener
Chapter 16
The Kidney...........................................................................................................................................................................253
Peter A. McAnulty
Chapter 17
Reproductive System Including Studies in Juvenile Minipigs.............................................................................................263
Peter A. McAnulty, Paul Barrow and Edward Marsden
CONTENTS vii
Chapter 18
The Endocrine System.........................................................................................................................................................277
Claudia Stark and Jakob Walter
Chapter 19
Skeletal System....................................................................................................................................................................283
Hideki Tsutsumi
Chapter 20
Ocular Examination and Background Observations...........................................................................................................293
Helmut Ehall
Chapter 21
Spontaneous/Background Pathology of Göttingen Minipig................................................................................................305
Zuhal Dincer and Mikala Skydsgaard
Section V
Genetics and Immunology
Chapter 22
A Comparative Assessment of the Pig, Mouse and Human Genomes: Structural and Functional Analysis
of Genes Involved in Immunity and Inflammation.............................................................................................................323
Harry D. Dawson
Chapter 23
The Immune System of Pigs: Structure and Function.........................................................................................................343
Patrick Haley
Chapter 24
Transplantation in Miniature Swine.....................................................................................................................................357
John S. Hanekamp, Raimon Duran-Struuck and David H. Sachs
Chapter 25
Xenotransplantation..............................................................................................................................................................373
Henk-Jan Schuurman, Melanie L. Graham, Thomas Spizzo, and Clive Patience
Chapter 26
Porcine Endogenous Retroviruses in Xenotransplantation: A Review of the Importance of PERVs in Porcine
Studies, with Particular Emphasis on the Minipig..............................................................................................................387
Linda Scobie and Olga Garkavenko
Chapter 27
Immunotoxicology: Studies in the Minipig.........................................................................................................................397
André H. Penninks and Geertje J.D. van Mierlo
vüi CONTENTS
Section VI
Disease Models
Chapter 28
Creation and Conservation of Genetically Modified Pigs: Applications to Genetic Disease Model
and Xenotransplantation.......................................................................................................................................................415
Hiroshi Nagashima, Hitomi Matsunari, and Kazuhiro Umeyama
Chapter 29
Stem Cell Research and Minipigs.........................................................................................................................................431
Vanessa J. Hall, Stoyan G. Petkov, and Poul Hyttel
Chapter 30
Minipig Models of Diabetes Mellitus..................................................................................................................................445
Dwight A. Bellinger, Elizabeth P. Merricks, and Timothy C. Nichols
Chapter 31
Minipig in Biomedical Research: Diet-Induced Atherosclerosis........................................................................................469
James R. Turk and M. Harold Laughlin
Chapter 32
Hemorrhage and Resuscitation Models Using the Miniature Swine....................................................................................479
John W. Burns and Charles E. Wade
Chapter 33
Oral Biology and Dental Models..........................................................................................................................................491
Susan W. Herring, Yiming Li, Yi Liu, Zi Jun Liu, Tracy E. Popowics,
Katherine L. Rafferty, and Songlin Wang
Chapter 34
Osteoporosis Model in Minipigs...........................................................................................................................................517
Hideki Tsutsumi, Satoshi Ikeda, and Toshitaka Nakamura
Chapter 35
Wound Healing Models.......................................................................................................................................................525
Peter Glerup
Chapter 36
The Minipig in Chemical, Biological, and Radiological Research......................................................................................533
Stanley W. Hulet, Maria Moroni, Mark H. Whitnall, and Robert J. Mioduszewski
Chapter 37
The Minipig and Pig in Medical Device Research...........................................................................................................549
Shayne C. Gad
CONTENTS ix
Section VII
Regulatory Perspective and Use of the Minipig in Developing Marketed Products
Chapter 38
Regulatory Aspects: Pharmaceuticals, Medical Devices, Food Additives: Minipigs and Global Safety Regulations.......565
Abigail Jacobs and Jan-Willem van der Laan
Chapter 39
Adverse Responses to Drugs in Man: Critical Comparison of Reported Toxicological
Findings in Minipigs and Humans.......................................................................................................................................573
Niels-Christian Ganderup
Chapter 40
Regulatory Acceptance of the Minipig in Non-Pharmaceutical Industry and Research....................................................595
Warren Harvey
Section VIII
New Horizons and perspectives
Chapter 41
Future Prospects: Possibilities and Perspectives..................................................................................................................619
Anthony D. Dayan
Index....................................................................................................................................................................................627
|
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| id | DE-604.BV042567447 |
| illustrated | Illustrated |
| indexdate | 2024-12-24T04:28:23Z |
| institution | BVB |
| isbn | 9781439811184 1439811180 |
| language | English |
| lccn | 2011039677 |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028001065 |
| oclc_num | 838842264 |
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| owner | DE-188 |
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| physical | XVII, 643 S., [46] S. Ill. 29 cm |
| publishDate | 2012 |
| publishDateSearch | 2012 |
| publishDateSort | 2012 |
| publisher | CRC Press/Taylor & Francis |
| record_format | marc |
| spellingShingle | The minipig in biomedical research miniature pigs cabt animal experiments cabt animal models cabt Animals, Laboratory Swine, Miniature Animal Welfare Biomedical Research methods Disease Models, Animal |
| title | The minipig in biomedical research |
| title_auth | The minipig in biomedical research |
| title_exact_search | The minipig in biomedical research |
| title_full | The minipig in biomedical research edited by Peter A. McAnulty ... |
| title_fullStr | The minipig in biomedical research edited by Peter A. McAnulty ... |
| title_full_unstemmed | The minipig in biomedical research edited by Peter A. McAnulty ... |
| title_short | The minipig in biomedical research |
| title_sort | the minipig in biomedical research |
| topic | miniature pigs cabt animal experiments cabt animal models cabt Animals, Laboratory Swine, Miniature Animal Welfare Biomedical Research methods Disease Models, Animal |
| topic_facet | miniature pigs animal experiments animal models Animals, Laboratory Swine, Miniature Animal Welfare Biomedical Research methods Disease Models, Animal |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028001065&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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