Sugar Chains Decoding the Functions of Glycans

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Veröffentlicht: Tokyo [u.a.] Springer Japan 2015
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adam_text SUGAR CHAINS / SUZUKI, TADASHI : 2015 ABSTRACT / INHALTSTEXT THIS BOOK PRESENTS THE LATEST BREAKTHROUGH RESULTS IN GLYCOBIOLOGY REGARDING THE ROLES OF GLYCANS IN RELATION TO QUALITY CONTROL AND TRANSPORT OF PROTEIN, THE IMMUNE SYSTEM, VIRAL INFECTION, STEM CELLS, THE NEURAL SYSTEM, AND VARIOUS DISEASES SUCH AS CANCER, DIABETES, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, MUSCULAR DYSTROPHY, AND SCHIZOPHRENIA. ALTHOUGH GLYCOSCIENCE HAS LONG BEEN REGARDED AS A VERY SPECIALIZED FIELD WITH NO SIMPLE ANALYTICAL METHOD, THE RECENT EXPLOSIVE PROGRESS IN RESEARCH CONTINUES TO PROVIDE LIMITLESS EVIDENCE THAT GLYCAN CHAINS ARE THE KEY COMPONENT IN VARIOUS BIOLOGICAL PHENOMENA. CELL SURFACE GLYCANS, FOR EXAMPLE, CHANGE WITH DEVELOPMENTAL STAGES OR ENVIRONMENTAL CONDITIONS AND THUS REPRESENT A “FACE” OF THE CELL THAT IS UTILIZED FOR IDENTIFICATION OF IPS AND ES CELLS AND AS BIOMARKERS IN DIAGNOSIS OR DETECTION OF CANCER. THIS BOOK COMPRISES 17 CHAPTERS, EACH OF WHICH POSES OUTSTANDING “GLYCO-RELATED” QUESTIONS ENABLING NON-SPECIALISTS TO HAVE A CLEARER IDEA ABOUT WHAT THE FUTURE DIRECTION FOR FURTHER INVESTIGATION OF GLYCANS IN THEIR OWN RESEARCH FIELDS WILL BE. ALSO INCLUDING BASIC INFORMATION TO UNDERSTAND THE NATURE OF GLYCANS, THIS TITLE SERVES AS AN EXCELLENT “TEXTBOOK” FOR RESEARCHERS IN DIVERSE RESEARCH FIELDS WHO ARE NOT FAMILIAR WITH, BUT NEVERTHELESS INTERESTED IN, GLYCAN CHAINS OR SUGAR CHAINS DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT. SUGAR CHAINS / SUZUKI, TADASHI : 2015 TABLE OF CONTENTS / INHALTSVERZEICHNIS 1 N-GLYCANS AND QUALITY CONTROL OF PROTEINS 2 GLYCAN-MEDIATED PROTEIN TRANSPORT FROM THE ENDOPLASMIC RETICULUM 3 GANGLIOSIDES AND T-CELL IMMUNITY 4 GANGLIOSIDES REGULATE TUMOR PROPERTIES: WITH FOCUS ON THE SUPPRESSION OF METASTASIS-ASSOCIATED PPGALNAC-T13 WITH GM1 5 ROLE OF GLYCANS IN VIRAL INFECTION 6 DISCOVERY AND APPLICATIONS OF A NOVEL HUMAN PLURIPOTENT STEM CELL-SPECIFIC LECTIN PROBE RBC2LCN 7 GLYCAN STRUCTURE AND NEURAL PLASTICITY 8 THE INVOLVEMENT OF MIDKINE, A HEPARIN-BINDING GROWTH FACTOR, IN CANCER DEVELOPMENT 9 TUMOR-ASSOCIATED GLYCANS AND THEIR FUNCTIONAL ROLES IN THE MULTISTEP PROCESS OF HUMAN CANCER PROGRESSION 10 MAMMALIAN SIALIDASE AND TUMOR DEVELOPMENT 11 ROLES OF GLYCANS IN IMMUNE EVASION FROM NK IMMUNITY 12 GLYCOMIC ANALYSIS OF CANCER 13 GLYCO-PREDISPOSING FACTOR OF DIABETES 14 MACROPHAGES GOVERN GANGLIOSIDE GM3 EXPRESSION IN ADIPOCYTES TO REGULATE ADIPOGENESIS AND INSULIN SIGNALING IN HOMEOSTATIC AND PATHOGENIC CONDITIONS 15 O-MANNOSYL GLYCAN AND MUSCULAR DYSTROPHY 16 GLYCANS AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) 17 Α1,6-FUCOSYLTRANSFERASE KNOCKOUT MICE AND SCHIZOPHRENIA-LIKE PHENOTYPE DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
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spellingShingle Sugar Chains Decoding the Functions of Glycans
Life sciences
Oncology
Immunology
Biochemistry
Life Sciences
Biochemistry, general
Cancer Research
Biowissenschaften
title Sugar Chains Decoding the Functions of Glycans
title_auth Sugar Chains Decoding the Functions of Glycans
title_exact_search Sugar Chains Decoding the Functions of Glycans
title_full Sugar Chains Decoding the Functions of Glycans Tadashi Suzuki, Kazuaki Ohtsubo, Naoyuki Taniguchi, ed.
title_fullStr Sugar Chains Decoding the Functions of Glycans Tadashi Suzuki, Kazuaki Ohtsubo, Naoyuki Taniguchi, ed.
title_full_unstemmed Sugar Chains Decoding the Functions of Glycans Tadashi Suzuki, Kazuaki Ohtsubo, Naoyuki Taniguchi, ed.
title_short Sugar Chains
title_sort sugar chains decoding the functions of glycans
title_sub Decoding the Functions of Glycans
topic Life sciences
Oncology
Immunology
Biochemistry
Life Sciences
Biochemistry, general
Cancer Research
Biowissenschaften
topic_facet Life sciences
Oncology
Immunology
Biochemistry
Life Sciences
Biochemistry, general
Cancer Research
Biowissenschaften
url https://doi.org/10.1007/978-4-431-55381-6
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