Organic chemistry in action the design of organic synthesis

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1. Verfasser: Serratosa, Fèlix (VerfasserIn)
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Amsterdam Elsevier 1996
Ausgabe:2nd ed
Schriftenreihe:Studies in organic chemistry (Elsevier Science Publishers) 51
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500 |a "With a copy of CHAOS and CHAOSBASE." 
500 |a The first edition of this book was welcomed with great enthusiasm by teachers and students. It therefore seemed opportune to publish a second, revised, updated and extended edition. Unfortunately, Professor F̈lix Serratosa died before he could complete this task. Some new material has been added, the more significant changes being: 1) The book has been restructured into two well-differentiated sections: Part A, dealing with conventional organic synthesis, and Part B, devoted exclusively to computer-assisted organic synthesis and based on the former Chapter 11 and Appendices 2, 3 and 4 of the first edition. As decided in advance, Part B was to be the sole responsibility of Dr. Josep Xicart, who prepared the first versions of the CHAOS (Computerisation and Heuristics Applied to Organic Synthesis) program under the direction of Professor Serratosa.  
500 |a 2) In Chapter 1, emphasis is placed on new objectives and targets, as well as on the role that organic synthesis should play in the future in new areas of supramolecular chemistry and bioorganic chemistry. 3) A more extended discussion on synthetic methods and strategies based on radical carbon-carbon bond-forming reactions has been included (Chapter 7). 4) Some new examples to illustrate the heuristic principles have been incorporated (Chapter 4). 5) The chapter on alicyclic stereoselection has been split into two chapters (9 and 10). Chapter 10, which is exclusively devoted to Sharpless's asymmetric epoxidation and dihyroxylation, has been written de novo. The most recent advances in catalytic stereoselective aldol are incorporated in Chapter 9.  
500 |a 6) In Chapter 11, which is new, the aim is to firstly, present a panoramic view of the most important methods for preparation of optically pure compounds in industrial scale (chirotechnology) and secondly, to give a brief insight into the new biological synthetic methodologies, such as the use of enzymes and catalytic monoclonal antibodies or abzymes, which are becoming more and more important and familiar to the synthetic organic chemist. 7) The chapter dealing with examples of retrosynthetic analysis and the corresponding total synthesis has been enlarged and includes new syntheses of natural products (Chapter 13). 8) The former Chapter 11 and Appendices 2, 3 and 4 devoted to computer assisted organic synthesis have been rewritten and constitute now Part B of the book.  
500 |a The following changes have been introduced: i) CHAOS version 3.0 for Macintosh and version 1.0 for PC Windows substitute CHAOS version 2.0 for IBM PC and compatibles, ii) The corresponding Instruction Manuals and Disconnection Tables of these new versions are included, iii) two 3ư inch diskettes with the new versions of CHAOS and CHAOSDBASE replace the diskette of version 2.0, iv) a new Appendix (Appendix B-1) with a brief introduction to Ugi's Theory of Constitutional Chemistry and to the programs EROS and IGOR has also been added. 9) The main improvements in CHAOS version 3.0 for Macintosh are: i) The unique numbering or canonical matrices, ii) new disconnections, which are more selective, iii) besides RINGS and SYNTHETICALLY SIGNIFICANT RINGS, the new version gives, if required, the PRIMARY RINGS.  
500 |a Other new options are SELECT and RESIZE in the menu EDIT, by which one can select part of a synthetic sequence or resize the molecule drawing, iv) the possibility to introduce new disconnections from inside the program CHAOS itself and work (if desired) with one's own chemistry, through CHAOSBASE. The aim of this program is to create DATABASES of new DISCONNECTIONS. Such DATABASES can be opened from the program CHAOS in such a manner that it allows to disconnect molecules according to the DISCONNECTIONS defined in the DATABASE (instead of disconnecting according to predefined ones implemented in CHAOS). 10) Mistakes and errors detected in the first edition have been corrected 
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650 4 |a Organic compounds / Synthesis 
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650 7 |a Organic compounds / Synthesis  |2 fast 
650 7 |a Organic compounds / Synthesis / Data processing  |2 fast 
650 7 |a Synthese (chemie)  |2 gtt 
650 7 |a Organische verbindingen  |2 gtt 
650 7 |a Ontwerpen  |2 gtt 
650 4 |a Chemie 
650 4 |a Datenverarbeitung 
650 4 |a Organic compounds  |x Synthesis 
650 4 |a Organic compounds  |x Synthesis  |x Data processing 
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Datensatz im Suchindex

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author Serratosa, Fèlix
author_facet Serratosa, Fèlix
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author_sort Serratosa, Fèlix
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dewey-hundreds 500 - Natural sciences and mathematics
dewey-ones 547 - Organic chemistry
dewey-raw 547/.2
dewey-search 547/.2
dewey-sort 3547 12
dewey-tens 540 - Chemistry and allied sciences
discipline Chemie / Pharmazie
edition 2nd ed
format Electronic
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spelling Serratosa, Fèlix Verfasser aut
Organic chemistry in action the design of organic synthesis part A, Fèlix Serratosa ; part B, Josep Xicart and Fèlix Serratosa
2nd ed
Amsterdam Elsevier 1996
1 Online-Ressource (xxv, 540 pages)
txt rdacontent
c rdamedia
cr rdacarrier
Studies in organic chemistry (Elsevier Science Publishers) 51
"With a copy of CHAOS and CHAOSBASE."
The first edition of this book was welcomed with great enthusiasm by teachers and students. It therefore seemed opportune to publish a second, revised, updated and extended edition. Unfortunately, Professor F̈lix Serratosa died before he could complete this task. Some new material has been added, the more significant changes being: 1) The book has been restructured into two well-differentiated sections: Part A, dealing with conventional organic synthesis, and Part B, devoted exclusively to computer-assisted organic synthesis and based on the former Chapter 11 and Appendices 2, 3 and 4 of the first edition. As decided in advance, Part B was to be the sole responsibility of Dr. Josep Xicart, who prepared the first versions of the CHAOS (Computerisation and Heuristics Applied to Organic Synthesis) program under the direction of Professor Serratosa.
2) In Chapter 1, emphasis is placed on new objectives and targets, as well as on the role that organic synthesis should play in the future in new areas of supramolecular chemistry and bioorganic chemistry. 3) A more extended discussion on synthetic methods and strategies based on radical carbon-carbon bond-forming reactions has been included (Chapter 7). 4) Some new examples to illustrate the heuristic principles have been incorporated (Chapter 4). 5) The chapter on alicyclic stereoselection has been split into two chapters (9 and 10). Chapter 10, which is exclusively devoted to Sharpless's asymmetric epoxidation and dihyroxylation, has been written de novo. The most recent advances in catalytic stereoselective aldol are incorporated in Chapter 9.
6) In Chapter 11, which is new, the aim is to firstly, present a panoramic view of the most important methods for preparation of optically pure compounds in industrial scale (chirotechnology) and secondly, to give a brief insight into the new biological synthetic methodologies, such as the use of enzymes and catalytic monoclonal antibodies or abzymes, which are becoming more and more important and familiar to the synthetic organic chemist. 7) The chapter dealing with examples of retrosynthetic analysis and the corresponding total synthesis has been enlarged and includes new syntheses of natural products (Chapter 13). 8) The former Chapter 11 and Appendices 2, 3 and 4 devoted to computer assisted organic synthesis have been rewritten and constitute now Part B of the book.
The following changes have been introduced: i) CHAOS version 3.0 for Macintosh and version 1.0 for PC Windows substitute CHAOS version 2.0 for IBM PC and compatibles, ii) The corresponding Instruction Manuals and Disconnection Tables of these new versions are included, iii) two 3ư inch diskettes with the new versions of CHAOS and CHAOSDBASE replace the diskette of version 2.0, iv) a new Appendix (Appendix B-1) with a brief introduction to Ugi's Theory of Constitutional Chemistry and to the programs EROS and IGOR has also been added. 9) The main improvements in CHAOS version 3.0 for Macintosh are: i) The unique numbering or canonical matrices, ii) new disconnections, which are more selective, iii) besides RINGS and SYNTHETICALLY SIGNIFICANT RINGS, the new version gives, if required, the PRIMARY RINGS.
Other new options are SELECT and RESIZE in the menu EDIT, by which one can select part of a synthetic sequence or resize the molecule drawing, iv) the possibility to introduce new disconnections from inside the program CHAOS itself and work (if desired) with one's own chemistry, through CHAOSBASE. The aim of this program is to create DATABASES of new DISCONNECTIONS. Such DATABASES can be opened from the program CHAOS in such a manner that it allows to disconnect molecules according to the DISCONNECTIONS defined in the DATABASE (instead of disconnecting according to predefined ones implemented in CHAOS). 10) Mistakes and errors detected in the first edition have been corrected
Includes bibliographical references anf index
Organic compounds / Synthesis
SCIENCE / Chemistry / Organic bisacsh
Organic compounds / Synthesis fast
Organic compounds / Synthesis / Data processing fast
Synthese (chemie) gtt
Organische verbindingen gtt
Ontwerpen gtt
Chemie
Datenverarbeitung
Organic compounds Synthesis
Organic compounds Synthesis Data processing
Organische Synthese (DE-588)4075695-6 gnd rswk-swf
Organische Synthese (DE-588)4075695-6 s
1\p DE-604
Xicart, Josep Sonstige oth
http://www.sciencedirect.com/science/book/9780444819352 Verlag Volltext
1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk
spellingShingle Serratosa, Fèlix
Organic chemistry in action the design of organic synthesis
Organic compounds / Synthesis
SCIENCE / Chemistry / Organic bisacsh
Organic compounds / Synthesis fast
Organic compounds / Synthesis / Data processing fast
Synthese (chemie) gtt
Organische verbindingen gtt
Ontwerpen gtt
Chemie
Datenverarbeitung
Organic compounds Synthesis
Organic compounds Synthesis Data processing
Organische Synthese (DE-588)4075695-6 gnd
subject_GND (DE-588)4075695-6
title Organic chemistry in action the design of organic synthesis
title_auth Organic chemistry in action the design of organic synthesis
title_exact_search Organic chemistry in action the design of organic synthesis
title_full Organic chemistry in action the design of organic synthesis part A, Fèlix Serratosa ; part B, Josep Xicart and Fèlix Serratosa
title_fullStr Organic chemistry in action the design of organic synthesis part A, Fèlix Serratosa ; part B, Josep Xicart and Fèlix Serratosa
title_full_unstemmed Organic chemistry in action the design of organic synthesis part A, Fèlix Serratosa ; part B, Josep Xicart and Fèlix Serratosa
title_short Organic chemistry in action
title_sort organic chemistry in action the design of organic synthesis
title_sub the design of organic synthesis
topic Organic compounds / Synthesis
SCIENCE / Chemistry / Organic bisacsh
Organic compounds / Synthesis fast
Organic compounds / Synthesis / Data processing fast
Synthese (chemie) gtt
Organische verbindingen gtt
Ontwerpen gtt
Chemie
Datenverarbeitung
Organic compounds Synthesis
Organic compounds Synthesis Data processing
Organische Synthese (DE-588)4075695-6 gnd
topic_facet Organic compounds / Synthesis
SCIENCE / Chemistry / Organic
Organic compounds / Synthesis / Data processing
Synthese (chemie)
Organische verbindingen
Ontwerpen
Chemie
Datenverarbeitung
Organic compounds Synthesis
Organic compounds Synthesis Data processing
Organische Synthese
url http://www.sciencedirect.com/science/book/9780444819352
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