The practice of medicinal chemistry
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Format: | Elektronisch E-Book |
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Sprache: | English |
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Amsterdam
Academic Press
2003
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Ausgabe: | 2nd ed |
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500 | |a Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists with little or no background in medicinal chemistry. These chemists must acquire a good knowledge of medicinal chemistry during their first years in the pharmaceutical/drug discovery industry. This book aims to be their practical handbook - a complete guide to the drug discovery process. The book reviews practical aspects of Medicinal Chemistry, emphasising the daily problems met by the medicinal chemist when dealing with lead discovery/identification methodologies, with structure-activity relationship studies aimed to scale up potency and target selectivity, and when optimising pharmacokinetic and pharmaceutical properties by means of ultimate chemical modifications. This is the second edition of The Practice of Medicinal Chemistry, the first edition being published in February 1996. The new edition is thoroughly revised, with around 30% new material, and refocussed to reflect the recent developments in genomics, proteomics, high throughput screening of compounds and drug solubilisation. An effort has been made to remove the overlap that exists in the previous edition and four new chapters have been introduced. * Written by experts in the field * The first edition of The Practice of Medicinal Chemistry, published in 1996, was nicknamed 'The Bible' by medicinal chemists. * The only available book dealing with the practical aspects of medicinal chemistry, from conception of the molecules through to the production of drugs * An essential practical handbook for the medicinal chemist, working in the pharmaceutical industry, with little or no background in medicinal chemistry-a complete guide to the drug discovery process | ||
500 | |a Includes bibliographical references and index | ||
650 | 4 | |a Chemistry, Pharmaceutical | |
650 | 4 | |a Models, Chemical | |
650 | 4 | |a Pharmaceutical Preparations / chemistry | |
650 | 4 | |a Chimie pharmaceutique | |
650 | 4 | |a Médicaments / Conception | |
650 | 7 | |a MEDICAL / Drug Guides |2 bisacsh | |
650 | 7 | |a MEDICAL / Pharmacology |2 bisacsh | |
650 | 7 | |a MEDICAL / Pharmacy |2 bisacsh | |
650 | 7 | |a MEDICAL / Nursing / Pharmacology |2 bisacsh | |
650 | 7 | |a Medische chemie |2 gtt | |
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650 | 7 | |a Structuur-activiteit-relatie |2 gtt | |
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650 | 7 | |a Farmacochemie |2 gtt | |
650 | 7 | |a Química farmacêutica |2 larpcal | |
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650 | 7 | |a Pharmaceutical chemistry |2 fast | |
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650 | 4 | |a Pharmaceutical chemistry | |
650 | 4 | |a Drugs |x Design | |
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Datensatz im Suchindex
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---|---|
any_adam_object | |
building | Verbundindex |
bvnumber | BV042308297 |
collection | ZDB-33-ESD ZDB-33-EBS |
ctrlnum | (OCoLC)162129495 (DE-599)BVBBV042308297 |
dewey-full | 615.19 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 615 - Pharmacology and therapeutics |
dewey-raw | 615.19 |
dewey-search | 615.19 |
dewey-sort | 3615.19 |
dewey-tens | 610 - Medicine and health |
discipline | Medizin |
edition | 2nd ed |
format | Electronic eBook |
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genre_facet | Einführung |
id | DE-604.BV042308297 |
illustrated | Not Illustrated |
indexdate | 2024-12-24T04:19:35Z |
institution | BVB |
isbn | 9780127444819 0127444815 9780080497778 0080497772 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027745289 |
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physical | 1 Online-Ressource (xiv, 768 p.) |
psigel | ZDB-33-ESD ZDB-33-EBS FAW_PDA_ESD FLA_PDA_ESD |
publishDate | 2003 |
publishDateSearch | 2003 |
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publisher | Academic Press |
record_format | marc |
spelling | The practice of medicinal chemistry edited by Camille G. Wermuth 2nd ed Amsterdam Academic Press 2003 1 Online-Ressource (xiv, 768 p.) txt rdacontent c rdamedia cr rdacarrier Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists with little or no background in medicinal chemistry. These chemists must acquire a good knowledge of medicinal chemistry during their first years in the pharmaceutical/drug discovery industry. This book aims to be their practical handbook - a complete guide to the drug discovery process. The book reviews practical aspects of Medicinal Chemistry, emphasising the daily problems met by the medicinal chemist when dealing with lead discovery/identification methodologies, with structure-activity relationship studies aimed to scale up potency and target selectivity, and when optimising pharmacokinetic and pharmaceutical properties by means of ultimate chemical modifications. This is the second edition of The Practice of Medicinal Chemistry, the first edition being published in February 1996. The new edition is thoroughly revised, with around 30% new material, and refocussed to reflect the recent developments in genomics, proteomics, high throughput screening of compounds and drug solubilisation. An effort has been made to remove the overlap that exists in the previous edition and four new chapters have been introduced. * Written by experts in the field * The first edition of The Practice of Medicinal Chemistry, published in 1996, was nicknamed 'The Bible' by medicinal chemists. * The only available book dealing with the practical aspects of medicinal chemistry, from conception of the molecules through to the production of drugs * An essential practical handbook for the medicinal chemist, working in the pharmaceutical industry, with little or no background in medicinal chemistry-a complete guide to the drug discovery process Includes bibliographical references and index Chemistry, Pharmaceutical Models, Chemical Pharmaceutical Preparations / chemistry Chimie pharmaceutique Médicaments / Conception MEDICAL / Drug Guides bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh MEDICAL / Nursing / Pharmacology bisacsh Medische chemie gtt Drug targeting gtt Structuur-activiteit-relatie gtt Receptoren gtt Farmacokinetica gtt Farmacochemie gtt Química farmacêutica larpcal Drugs / Design fast Pharmaceutical chemistry fast Medizin Pharmaceutical chemistry Drugs Design Klinische Chemie (DE-588)4135255-5 gnd rswk-swf Pharmazeutische Chemie (DE-588)4132158-3 gnd rswk-swf 1\p (DE-588)4151278-9 Einführung gnd-content Pharmazeutische Chemie (DE-588)4132158-3 s 2\p DE-604 Klinische Chemie (DE-588)4135255-5 s 3\p DE-604 Wermuth, C. G. Sonstige oth http://www.sciencedirect.com/science/book/9780127444819 Verlag Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 3\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
spellingShingle | The practice of medicinal chemistry Chemistry, Pharmaceutical Models, Chemical Pharmaceutical Preparations / chemistry Chimie pharmaceutique Médicaments / Conception MEDICAL / Drug Guides bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh MEDICAL / Nursing / Pharmacology bisacsh Medische chemie gtt Drug targeting gtt Structuur-activiteit-relatie gtt Receptoren gtt Farmacokinetica gtt Farmacochemie gtt Química farmacêutica larpcal Drugs / Design fast Pharmaceutical chemistry fast Medizin Pharmaceutical chemistry Drugs Design Klinische Chemie (DE-588)4135255-5 gnd Pharmazeutische Chemie (DE-588)4132158-3 gnd |
subject_GND | (DE-588)4135255-5 (DE-588)4132158-3 (DE-588)4151278-9 |
title | The practice of medicinal chemistry |
title_auth | The practice of medicinal chemistry |
title_exact_search | The practice of medicinal chemistry |
title_full | The practice of medicinal chemistry edited by Camille G. Wermuth |
title_fullStr | The practice of medicinal chemistry edited by Camille G. Wermuth |
title_full_unstemmed | The practice of medicinal chemistry edited by Camille G. Wermuth |
title_short | The practice of medicinal chemistry |
title_sort | the practice of medicinal chemistry |
topic | Chemistry, Pharmaceutical Models, Chemical Pharmaceutical Preparations / chemistry Chimie pharmaceutique Médicaments / Conception MEDICAL / Drug Guides bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh MEDICAL / Nursing / Pharmacology bisacsh Medische chemie gtt Drug targeting gtt Structuur-activiteit-relatie gtt Receptoren gtt Farmacokinetica gtt Farmacochemie gtt Química farmacêutica larpcal Drugs / Design fast Pharmaceutical chemistry fast Medizin Pharmaceutical chemistry Drugs Design Klinische Chemie (DE-588)4135255-5 gnd Pharmazeutische Chemie (DE-588)4132158-3 gnd |
topic_facet | Chemistry, Pharmaceutical Models, Chemical Pharmaceutical Preparations / chemistry Chimie pharmaceutique Médicaments / Conception MEDICAL / Drug Guides MEDICAL / Pharmacology MEDICAL / Pharmacy MEDICAL / Nursing / Pharmacology Medische chemie Drug targeting Structuur-activiteit-relatie Receptoren Farmacokinetica Farmacochemie Química farmacêutica Drugs / Design Pharmaceutical chemistry Medizin Drugs Design Klinische Chemie Pharmazeutische Chemie Einführung |
url | http://www.sciencedirect.com/science/book/9780127444819 |
work_keys_str_mv | AT wermuthcg thepracticeofmedicinalchemistry |