Alkaloids a treasury of poisons and medicines
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| Hauptverfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Academic Press
2015
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
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| 100 | 1 | |a Funayama, Shinji |d 1951- |e Verfasser |0 (DE-588)1063138302 |4 aut | |
| 245 | 1 | 0 | |a Alkaloids |b a treasury of poisons and medicines |c by Shinji Funayama ; Geoffrey A. Cordell |
| 264 | 1 | |a Amsterdam [u.a.] |b Academic Press |c 2015 | |
| 300 | |a X, 284 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 500 | |a Originally in Japanese. - Includes bibliographical references and index | ||
| 650 | 0 | 7 | |a Alkaloide |0 (DE-588)4068543-3 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Alkaloide |0 (DE-588)4068543-3 |D s |
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| 700 | 1 | |a Cordell, Geoffrey A. |d 1946- |e Verfasser |0 (DE-588)1210511789 |4 aut | |
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Datensatz im Suchindex
| DE-BY-UBR_call_number | 86/VK 8620 F979 |
|---|---|
| DE-BY-UBR_katkey | 5902804 |
| DE-BY-UBR_location | 86 |
| DE-BY-UBR_media_number | 069039953866 |
| _version_ | 1822697762129444864 |
| adam_text | CONTENTS
Foreword jx
Introduction !
1. The Definition of an Aikaioid 2
2. Classification of Alkaloids 6
3. Humans and Alkaloids 0
4. Development of Pharmacognosy and Natural Product Chemistry, and
Alkaloids 12
5. Brief History of Japanese Pharmaceutical Sciences and Alkaloids 16
6. CNS Stimulation and Alkaloids 18
1. Alkaloids Derived from Phenylalanine and Tyrosine 21
1.1 Phenylethylamines (Phenethylamines) 22
1.2 l֊DOPA and Dopamine 25
1.3 Thyroid Gland and Thyroxine 27
1.4 Coclaurine and Coclaurine֊Type Alkaloids 29
1.5 Tubocurare and d-Tubocurarine 32
1.6 Aporphine-Type Alkaloids 34
1.7 Aristolochia spp. and Aristolochic Acid 37
1.8 Phellodendron omurense and Berberine 40
1.9 Cheiidonium majus and Chelidonine 43
1.10 Opium and Morphine 45
1A 1 Colchicum and Colchicine 49
1.12 Erythrina indica and Erythrina Alkaloids 52
1.13 Lycoris spp. and Lycorine 55
1.14 Cephaelis ipecacuanha and Emetine 59
2. Alkaloids Derived from Tryptophan 63
2.1 Serotonin 64
2.2 Auxin and lndo!e-3-Acetic Add 65
2.3 Teonanacatl and Psilocybin 66
2.4 Indigo and the Ancient Purple 67
2.5 Calabar Beans and Physostigmine 69
2.6 Harmala and Harmine 70
2.7 Picrasma sp. and Nigakinone
2.8 C/erodendron and Trichotomine 73
2.9 iboga and Ibogaine 75
v
vi
Contents
2.10 Rauvolfia and Reserpine 76
2.11 Yohimbe and Yohimbine 78
2.12 Comptotheco and Camptothecin SO
2.13 Uncaria and Rhynchophylline 82
2.14 Nux Vomica and Strychnine 83
2.15 Calabash Curare and C~Curarine and C-Toxiferine i 84
2.16 Ergot, Ergot Alkaloids, and LSD 85
2.17 Cinchona and Quinine 88
2.18 Catharanthus roseus and VLB and VCR 90
2.19 Euodia rutaecarpa and Evodiamine and Rutaecarpine 93
2.20 Athlete s Foot and Pyrroinitrin 95
2.21 Anthramycin and Tomaynnycin 97
2.22 Streptonigrin 99
2.23 Staurosporine 101
3. Alkaloids Derived from Ornithine and Arginine 103
3.1 Tobacco and Nicotine 103
3.2 Belladonna and Atropine 106
33 Coca Leaves and Cocaine 111
3.4 Senecio and Pyrroiizidine Alkaloids 114
3.5 Alkaloids Derived from Polyamines 119
3.6 Putrescine and Piriferine 121
3.7 Spermidine and Agrobactin 122
3.8 Spermine and Ephedradine 122
3.9 Fugu and Tetrodotoxin 125
4. Alkaloids Derived from Lysine 129
4.1 Pepper (Piper nigrum) and Piperine 130
4.2 Punica granatum and Pelletierine 131
43 Tobacco and Anabasine 134
4.4 Lobelia inflata (Indian Tobacco) and Lobeiine 135
4.5 Sophora flavescens and Matrine 136
4.6 Common broom (Cytisus scoparius) and Sparteine 139
5. Alkaloids Derived from Proline 141
5.1 Serratia and Prodigiosin 142
5.2 Stachydrine 144
53 Pyrrole-2-carboxylic Acid 144
Contents
vii
6. Alkaloids Derived from Glutamic Acid 147
6.1 Y-Aminobutyric Acid 147
6.2 Digenea simplex and Kainic Acid 149
6.3 Clitocybe acromelalga and AcromeJic Acid 151
6.4 Amanitapantherina and Ibotenic Acid 153
7. Alkaloids Derived from Histidine 155
7.1 Histamine 155
7.2 Jaborandi and Pilocarpine 157
8. Alkaloids Derived from 2,3- Diaminopropionic Acid 159
8.1 Quisqualis indica Fruits and Quisqualic Acid 159
9. Compounds Derived from Anthranilic Acid 163
9.1 Orixajaponica and Quinoline Alkaloids 164
9.2 Quinoline Alkaloids of Microbial Origin 168
9.3 Acronycine and Acridone Alkaloids 169
9.4 Quinoline Alkaloids Isolated from Higher Plants other
than the Rutaceae Family 172
9.5 Febrifugine and Related Alkaloids 173
9.6 Harmala Alkaloids and Vasicine (Peganine) 176
9.7 Phenaztne Alkaloids Derived from Microorganisms 178
10. Alkaloids Derived from Nicotinic Acid 181
10.1 Nicotine and Anabasine 184
10.2 Niacin and Vitamin B6 186
10.3 Areca Nut and Arecoline 189
10.4 Castor and Ricinine 190
11. Alkaloids Derived from Nucleic Acids and Related Compounds 193
11.1 Purine Bases and Caffeine 194
11.2 Pyrimidine Bases, 5-FJuorouracii, and Vitamin B, 202
11.3 Pteridine Skeleton and Folic Acid 206
12. Alkaloids Possessing the Porphine Skeleton 209
12.1 Heme and Chlorophyll 210
12.2 Vitamin B12 216
viii Contents
13. Alkaloids Derived from an m-C7N Unit 219
13.1 Mitomycin C 220
13.2 Naphthalenoid Ansamycins and Rifampicin 222
13.3 Benzenoid Ansamycins and Maytansine 225
13.4 The Biosynthesis-Stereochemistry Mode! (Celmer s Mode!)
of the Ansamycins 228
14. Alkaloids Derived from Terpenoids 233
14.1 Actinidia polygama and Actinidine 236
14.2 Gentiana scabra and Gentianine 238
14.3 Rhizome of Nupharjaponicum and Sesquiterpene Alkaloids 240
14.4 Aconitum and Aconitine Alkaloids 241
14.5 Taxus cusp ¡data and Taxol 244
14.6 Pochysandro terminalis and Buxaceae Alkaloids 246
14.7 Holarrhena antidysenterica and Conessine 248
14.8 Potato and Solanine 248
14.9 Fritillaria and Veratrum Alkaloids 250
14.10 Arrow Toxins, Toxic Birds, and Batrachotoxin 253
15. Alkaloids Derived from Polyketides 257
15.1 Hemlock and Coniine 257
15.2 Nigrifactin and Piericidins 260
16. Alkaloids Derived from a C -C, Unit 263
o i
16.1 Ephedra Alkaloids 264
16.2 Khat and Ephedra Alkaloids 267
16.3 Naphthalene-Isoquinoline Alkaloids 270
16.4 Red Pepper and Capsaicin 271
Index 275
Alkaloids: A Treasury of Poisons and Medicines offers an accessible history
and summary of the diversity, importance, and biosynthesis of alkaloids.
This book is an expanded English version of the original, popular Japanese
title. Alkaloids represent one of the major classes of biologically active
natural products, occurring widely in nature and present in plants, fungi,
bacteria, marine organisms, mammals, and humans.They are important as
pharmaceutical agents, biological standards, and toxins. This book reviews
the chemical, biological, and ecological explanations for the alkaloid class
of natural products.
Key features:
• Classifies and lists alkaloids from natural sources
• Describes the occurrence and main biosynthetic pathways of alkaloids
• Indicates important uses and bioactivity of alkaloids
• Discusses alkaloids isolated from the medicinal plants used in Japanese
Kampo medicine
|
| any_adam_object | 1 |
| author | Funayama, Shinji 1951- Cordell, Geoffrey A. 1946- |
| author_GND | (DE-588)1063138302 (DE-588)1210511789 |
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| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 572 - Biochemistry |
| dewey-raw | 572/.549 |
| dewey-search | 572/.549 |
| dewey-sort | 3572 3549 |
| dewey-tens | 570 - Biology |
| discipline | Chemie / Pharmazie Biologie |
| format | Book |
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| id | DE-604.BV042228210 |
| illustrated | Illustrated |
| indexdate | 2024-12-24T04:17:17Z |
| institution | BVB |
| isbn | 9780124173026 0124173020 0128021586 9780128021583 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027666566 |
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| owner_facet | DE-11 DE-19 DE-BY-UBM DE-355 DE-BY-UBR |
| physical | X, 284 S. Ill., graph. Darst. |
| publishDate | 2015 |
| publishDateSearch | 2015 |
| publishDateSort | 2015 |
| publisher | Academic Press |
| record_format | marc |
| spellingShingle | Funayama, Shinji 1951- Cordell, Geoffrey A. 1946- Alkaloids a treasury of poisons and medicines Alkaloide (DE-588)4068543-3 gnd |
| subject_GND | (DE-588)4068543-3 |
| title | Alkaloids a treasury of poisons and medicines |
| title_auth | Alkaloids a treasury of poisons and medicines |
| title_exact_search | Alkaloids a treasury of poisons and medicines |
| title_full | Alkaloids a treasury of poisons and medicines by Shinji Funayama ; Geoffrey A. Cordell |
| title_fullStr | Alkaloids a treasury of poisons and medicines by Shinji Funayama ; Geoffrey A. Cordell |
| title_full_unstemmed | Alkaloids a treasury of poisons and medicines by Shinji Funayama ; Geoffrey A. Cordell |
| title_short | Alkaloids |
| title_sort | alkaloids a treasury of poisons and medicines |
| title_sub | a treasury of poisons and medicines |
| topic | Alkaloide (DE-588)4068543-3 gnd |
| topic_facet | Alkaloide |
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