A Systems Theoretic Approach to Systems and Synthetic Biology 2 Analysis and Design of Cellular Systems
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| Format: | Elektronisch E-Book |
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| Sprache: | English |
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Dordrecht [u.a.]
Springer
2014
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| Online-Zugang: | TUM01 UBT01 Volltext Inhaltsverzeichnis Abstract |
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| 245 | 1 | 0 | |a A Systems Theoretic Approach to Systems and Synthetic Biology |n 2 |p Analysis and Design of Cellular Systems |c Vishwesh V. Kulkarni ; Guy-Bart Stan ; Karthik Raman, ed. |
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Datensatz im Suchindex
| DE-BY-TUM_katkey | 2023410 |
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| DE-BY-TUM_local_url | Verlag https://doi.org/10.1007/978-94-017-9047-5 |
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| adam_text | A SYSTEMS THEORETIC APPROACH TO SYSTEMS AND SYNTHETIC BIOLOGY II:
ANALYSIS AND DESIGN OF CELLULAR SYSTEMS
/
: 2014
TABLE OF CONTENTS / INHALTSVERZEICHNIS
1 NETWORK BIOMARKER CONSTRUCTION FOR MOLECULAR INVESTIGATION AND
DIAGNOSIS OF LUNG CANCERVIA MICROARRAY DATA
2 THE IMPACT OF NEXT GENERATION SEQUENCING TECHNOLOGY ON BACTERIAL
GENOMICS
3 SENSITIVITY ANALYSIS OF CIRCADIAN ENTRAINMENT IN THE SPACE OF PHASE
RESPONSE CURVES
4 MODELLING AND ANALYSIS OF FEEDBACK CONTROL MECHANISMS UNDERLYING
OSMOREGULATION IN YEAST
5 ANALYSIS OF SYNCHRONIZING BIOCHEMICAL NETWORKS VIA INCREMENTAL
DISSIPATIVITY
6 ROBUSTNESS MODEL VALIDATION OF BISTABILITY IN BIOMOLECULAR SYSTEMS
7 META-DNA: A DNA-BASED APPROACH TO SYNTHETIC BIOLOGY
8 TOWARDS MODELING AUTOMATION FOR SYNTHETIC BIOLOGY
9 AN INVESTIGATION OF SIGNAL TRANSDUCTION AND IRREVERSIBLE DECISION
MAKING THROUGH MONOSTABLE AND BISTABLE SWITCHES
10 FROM SPECIFICATION TO PARAMETERS: A LINEARIZATION APPROACH
11 SIMPLIFIED COMPUTATIONAL DESIGN OF DIGITAL SYNTHETIC GENE CIRCUITS
12 SYNTHETIC BIOCHEMICAL DEVICES FOR PROGRAMMABLE DYNAMIC BEHAVIOR
INDEX
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
A SYSTEMS THEORETIC APPROACH TO SYSTEMS AND SYNTHETIC BIOLOGY II:
ANALYSIS AND DESIGN OF CELLULAR SYSTEMS
/
: 2014
ABSTRACT / INHALTSTEXT
THE COMPLEXITY OF BIOLOGICAL SYSTEMS HAS INTRIGUED SCIENTISTS FROM MANY
DISCIPLINES AND HAS GIVEN BIRTH TO THE HIGHLY INFLUENTIAL FIELD OF
SYSTEMS BIOLOGY WHEREIN A WIDE ARRAY OF MATHEMATICAL TECHNIQUES, SUCH AS
FLUX BALANCE ANALYSIS, AND TECHNOLOGY PLATFORMS, SUCH AS NEXT GENERATION
SEQUENCING, IS USED TO UNDERSTAND, ELUCIDATE, AND PREDICT THE FUNCTIONS
OF COMPLEX BIOLOGICAL SYSTEMS. MORE RECENTLY, THE FIELD OF SYNTHETIC
BIOLOGY, I.E., DE NOVO ENGINEERING OF BIOLOGICAL SYSTEMS, HAS EMERGED.
SCIENTISTS FROM VARIOUS FIELDS ARE FOCUSING ON HOW TO RENDER THIS
ENGINEERING PROCESS MORE PREDICTABLE, RELIABLE, SCALABLE, AFFORDABLE,
AND EASY. SYSTEMS AND CONTROL THEORY IS A BRANCH OF ENGINEERING AND
APPLIED SCIENCES THAT RIGOROUSLY DEALS WITH THE COMPLEXITIES AND
UNCERTAINTIES OF INTERCONNECTED SYSTEMS WITH THE OBJECTIVE OF
CHARACTERISING FUNDAMENTAL SYSTEMIC PROPERTIES SUCH AS STABILITY,
ROBUSTNESS, COMMUNICATION CAPACITY, AND OTHER PERFORMANCE
METRICS.SYSTEMS AND CONTROL THEORY ALSO STRIVES TO OFFER CONCEPTS AND
METHODS THAT FACILITATE THE DESIGN OF SYSTEMS WITH RIGOROUS GUARANTEES
ON THESE PROPERTIES. OVER THE LAST 100 YEARS, IT HAS MADE STELLAR
THEORETICAL AND TECHNOLOGICAL CONTRIBUTIONS IN DIVERSE FIELDS SUCH AS
AEROSPACE, TELECOMMUNICATION, STORAGE, AUTOMOTIVE, POWER SYSTEMS, AND
OTHERS. CAN IT HAVE, OR EVOLVE TO HAVE, A SIMILAR IMPACT IN BIOLOGY? THE
CHAPTERS IN THIS BOOK DEMONSTRATE THAT, INDEED, SYSTEMS AND CONTROL
THEORETIC CONCEPTS AND TECHNIQUES CAN HAVE A SIGNIFICANT IMPACT IN
SYSTEMS AND SYNTHETIC BIOLOGY. VOLUME II CONTAINS CHAPTERS CONTRIBUTED
BY LEADING RESEARCHERS IN THE FIELD OF SYSTEMS AND SYNTHETIC BIOLOGY
THAT CONCERN MODELING PHYSIOLOGICAL PROCESSES AND BOTTOM-UP
CONSTRUCTIONS OF SCALABLE BIOLOGICAL SYSTEMS.THE MODELING PROBLEMS
INCLUDE CHARACTERISATION AND SYNTHESIS OF MEMORY, UNDERSTANDING HOW
HOMOEOSTASIS IS MAINTAINED IN THE FACE OF SHOCKS AND RELATIVELY GRADUAL
PERTURBATIONS, UNDERSTANDING THE FUNCTIONING AND ROBUSTNESS OF
BIOLOGICAL CLOCKS SUCH AS THOSE AT THE CORE OF CIRCADIAN RHYTHMS, AND
UNDERSTANDING HOW THE CELL CYCLES CAN BE REGULATED, AMONG OTHERS. SOME
OF THE BOTTOM-UP CONSTRUCTION PROBLEMS INVESTIGATED IN VOLUME II ARE AS
FOLLOWS: HOW SHOULD BIOMACROMOLECULES, PLATFORMS, AND SCALABLE
ARCHITECTURES BE CHOSEN AND SYNTHESISED IN ORDER TO BUILD PROGRAMMABLE
DE NOVO BIOLOGICAL SYSTEMS? WHAT ARE THE TYPES OF CONSTRAINED
OPTIMISATION PROBLEMS ENCOUNTERED IN THIS PROCESS AND HOW CAN THESE BE
SOLVED EFFICIENTLY? AS THE EMINENT COMPUTER SCIENTIST DONALD KNUTH PUT
IT, BIOLOGY EASILY HAS 500 YEARS OF EXCITING PROBLEMS TO WORK ON .THIS
EDITED BOOK PRESENTS BUT A SMALL FRACTION OF THOSE FOR THE BENEFIT OF
(1) SYSTEMS AND CONTROL THEORISTS INTERESTED IN MOLECULAR AND CELLULAR
BIOLOGY AND (2) BIOLOGISTS INTERESTED IN RIGOROUS MODELLING, ANALYSIS
AND CONTROL OF BIOLOGICAL SYSTEMS
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
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| illustrated | Not Illustrated |
| indexdate | 2024-11-25T17:51:13Z |
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| isbn | 9789401790475 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027491639 |
| oclc_num | 890471065 |
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| publishDate | 2014 |
| publishDateSearch | 2014 |
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| publisher | Springer |
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| spellingShingle | A Systems Theoretic Approach to Systems and Synthetic Biology Biologisches Modell (DE-588)4726968-6 gnd Synthetische Biologie (DE-588)7684405-5 gnd Systembiologie (DE-588)4809615-5 gnd |
| subject_GND | (DE-588)4726968-6 (DE-588)7684405-5 (DE-588)4809615-5 |
| title | A Systems Theoretic Approach to Systems and Synthetic Biology |
| title_auth | A Systems Theoretic Approach to Systems and Synthetic Biology |
| title_exact_search | A Systems Theoretic Approach to Systems and Synthetic Biology |
| title_full | A Systems Theoretic Approach to Systems and Synthetic Biology 2 Analysis and Design of Cellular Systems Vishwesh V. Kulkarni ; Guy-Bart Stan ; Karthik Raman, ed. |
| title_fullStr | A Systems Theoretic Approach to Systems and Synthetic Biology 2 Analysis and Design of Cellular Systems Vishwesh V. Kulkarni ; Guy-Bart Stan ; Karthik Raman, ed. |
| title_full_unstemmed | A Systems Theoretic Approach to Systems and Synthetic Biology 2 Analysis and Design of Cellular Systems Vishwesh V. Kulkarni ; Guy-Bart Stan ; Karthik Raman, ed. |
| title_short | A Systems Theoretic Approach to Systems and Synthetic Biology |
| title_sort | a systems theoretic approach to systems and synthetic biology analysis and design of cellular systems |
| topic | Biologisches Modell (DE-588)4726968-6 gnd Synthetische Biologie (DE-588)7684405-5 gnd Systembiologie (DE-588)4809615-5 gnd |
| topic_facet | Biologisches Modell Synthetische Biologie Systembiologie |
| url | https://doi.org/10.1007/978-94-017-9047-5 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027491639&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027491639&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV042050527 |
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