Cerebral angiogenesis methods and protocols

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Veröffentlicht: New York Humana Press 2014
Schriftenreihe:Methods in molecular biology 1135
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adam_text Titel: Cerebral angiogenesis Autor: Milner, Richard Jahr: 2014 Contents Preface.......................................................... v Contributors.......................................................... xi Part I Overview of Cerebral Angiogenesis 1 Cerebral Angiogenesis During Development: Who Is Conducting the Orchestra?................................. 3 Ina M. Wittko-Schneider, Fabian T. Schneider, and Karl H. Plate 2 Cerebral Angiogenesis: A Realistic Therapy for Ischemic Disease?.......... 21 David A. Greenberg 3 Vascular Normalization in Cerebral Angiogenesis: Friend or Foe?.......... 25 Jisook Lee, Andrew Baird, and Brian P. Eliceiri 4 Pericytes and Adaptive Angioplasticity: The Role of Tumor Necrosis Factor-Like Weak Inducer of Apoptosis (TWEAK)..................... 35 Paula Dore-Duffy Part II Animal Models of Cerebral Angiogenesis 5 Analysis of Angiogenesis in the Developing Mouse Central Nervous System......................................... 55 Nicole Ziejjler, Karl H. Plate, and Stefan Liebner 6 Hypoxia-Induced Angiogenesis and Capillary Density Determination....... 69 Constantinos P. Tsipis, Xiaoyan Sun, Kui Xu, and Joseph C. LaManna 7 The Middle Cerebral Artery Occlusion Model of Transient Focal Cerebral Ischemia.............................................. 81 Fudong Liu and Louise D. McCullough 8 A Mouse Model of Chronic Cerebral Hypoperfusion Characterizing Features of Vascular Cognitive Impairment........................... 95 Masafumi Ihara, Akihiko Taguchi, Takakuni Maki, Kazuo Washida, and Hidekazu Tomimoto 9 A Mouse Model of Permanent Focal Ischemia: Distal Middle Cerebral Artery Occlusion............................. 103 Kristian P. Doyle and Marion S. Buckwalter 10 A Method of Inducing Global Cerebral Ischemia...................... Ill Gina Hadley, Michaiis Papadakis, and Alastair M. Buchan 11 Induction of Cerebral Arteriogenesis in Mice......................... 121 André Duelsner, Nora Gatzke, Anja Bondke Persson, and Ivo R. Buschmann vii viii Contents 12 Vessel Painting Technique for Visualizing the Cerebral Vascular Architecture of the Mouse....................... 127 Shea Hughes, Oleksandr Dashkin, and Richard Anthony DeFazio 13 Examining Cerebral Angiogenesis in Response to Physical Exercise......... 139 KierstenL. Berggren, Jacob J.M. Kay, and Rodney A. Swain Part III Methods of Examining Cerebral Angiogenesis 14 Histological Assessment of Angiogenesis in the Hypoxic Central Nervous System............................. 157 Moisés Freitas-Andrade, Jacqueline Slinn, Claudie Charlebois, and Maria J. Moreno 15 Examining Vascular Remodeling in the Hypoxic Central Nervous System .... 177 Amin Boroujerdi, Jennifer V. Welser-Alves, and Richard Milner 16 Analysis of Cerebral Angiogenesis in Human Glioblastomas.............. 187 Michel Mittelbronn, Peter Baumgarten, Patrick N. Harter, and Karl H. Plate 17 Quantitative Cerebral Blood Flow Measurements Using MRI............. 205 Eric R. Muir, Lora Talley Watts, Tash Vardhan Tiwari, Andrew Bresnen, Qiang Shen, and Timothy Q. Duong 18 Fluorescent Angiogenesis Models Using Gelfoam® Implanted in Transgenic Mice Expressing Fluorescent Proteins............ 213 Robert M. Hoffman 19 Laser Speckle Contrast Imaging to Measure Changes in Cerebral Blood Flow.......................................... 223 Ian PL Winship 20 Laser Doppler Flowmetry to Measure Changes in Cerebral Blood Flow..... 237 Brad A. Sutherland, Tamer Rabie, and Alastair M. Buchau Part IV Determining the Role of Candidate Genes in Cerebral Angiogenesis 21 Defining the Role of HIF and Its Downstream Mediators in Hypoxic-Induced Cerebral Angiogenesis........................... 251 Xiaoyan Sun, Constantinos P. Tsipis, Girriso F. Benderro, Kui Xu, and Joseph C. LaManna 22 Inducible Gene Deletion in Glial Cells to Study Angiogenesis in the Central Nervous System.................................... 261 Hye Shin Lee and Joseph H. McCarty 23 Bone Marrow Chimera Experiments to Determine the Contribution of Hematopoietic Stem Cells to Cerebral Angiogenesis.................. 275 Marcia Regina Machein and Karl H. Plate Contents ix 24 Novel Methods for Accurate Identification, Isolation, and Genomic Analysis of Symptomatic Microenvironments in Atherosclerotic Arteries..... 289 Mark Slevin, Marthel Baldellou, Elspeth Hill, Yvonne Alexander, Garry McDowell, Christopher Murgatroyd, Michael Carroll, Hans Degens, Jerzy Krupinski, Norma Rovira, Mohammad Chowdhury, Ferdinand Serracino-Inglott, and Lina Badimon Part V Stimulation of Cerebral Angiogenesis by Gene Delivery 25 Induction of Brain Arteriovenous Malformation in the Adult Mouse........ 309 Wanqiu Chen, William L. Young, and Hua Su 26 Stimulation of Cerebral Angiogenesis by Gene Delivery................. 317 Yaohui Tang, Yaning Li, Xiaojie Lin, Peng Miao, Yongting Wang, and Guo-Yuan Yang 27 Investigating the Role of Perlecan Domain V in Post-Ischemic Cerebral Angiogenesis............................. 331 Aileen Marcelo and Gregory Bix Part VI Methods to Study Cerebral Angiogenesis In Vitro 28 Isolation and Culture of Primary Mouse Brain Endothelial Cells........... 345 Jennifer V. Welser-Alves, Amin Boroujerdi, and Richard Milner 29 Purification of Endothelial Cells from Rat Brain....................... 357 Jinhua Luo, Xiangling Yin, Alma Sanchez, Debjani Tripathy, Joseph Martinez, and Paula Grammas 30 Generation of Primary Cultures of Bovine Brain Endothelial Cells and Setup of Cocultures with Rat Astrocytes.......................... 365 Hans C. Helms and Birger Brodin 31 Isolation and Culture of Primary Pericytes from Mouse Brain............. 383 Amin Boroujerdi, Ulrich Tigges, Jennifer V. Welser-Alves, and Richard Milner 32 Assays to Examine Endothelial Cell Migration, Tube Formation, and Gene Expression Profiles........................ 393 Shuzhen Guo, Josephine Lok, Yi Liu, Kazuhide Hayakawa, Wendy Leung, Changhong Xing, Xunming Ji, and Eng H. Lo 33 A Neurovascular Blood-Brain Barrier In Vitro Model................... 403 Christoph M. Zehendner, Robin White, Jana Hedrich, and Heiko J. Luhmann 34 In Vitro Models of the Blood-Brain Barrier.......................... 415 Cathrin J. Czupalla, Stefan Liebner, and Kavi Devraj Index............................................................... 439
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spelling Cerebral angiogenesis methods and protocols ed. by Richard Milner
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spellingShingle Cerebral angiogenesis methods and protocols
Methods in molecular biology
Gehirn (DE-588)4019752-9 gnd
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title Cerebral angiogenesis methods and protocols
title_auth Cerebral angiogenesis methods and protocols
title_exact_search Cerebral angiogenesis methods and protocols
title_full Cerebral angiogenesis methods and protocols ed. by Richard Milner
title_fullStr Cerebral angiogenesis methods and protocols ed. by Richard Milner
title_full_unstemmed Cerebral angiogenesis methods and protocols ed. by Richard Milner
title_short Cerebral angiogenesis
title_sort cerebral angiogenesis methods and protocols
title_sub methods and protocols
topic Gehirn (DE-588)4019752-9 gnd
Angiogenese (DE-588)4142449-9 gnd
topic_facet Gehirn
Angiogenese
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