Marine microbiology bioactive compounds and biotechnological applications
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| 245 | 1 | 0 | |a Marine microbiology |b bioactive compounds and biotechnological applications |c ed. by Se-Kwon Kim |
| 264 | 1 | |a Weinheim |b Wiley-VCH-Verl. |c 2013 | |
| 300 | |a XXIX, 549 S. |b Ill., graph. Darst. |c 25 cm | ||
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Datensatz im Suchindex
| DE-BY-TUM_call_number | 0302 BIO 250f 2013 A 6278 |
|---|---|
| DE-BY-TUM_katkey | 1954500 |
| DE-BY-TUM_location | 03 |
| DE-BY-TUM_media_number | 040080404015 |
| _version_ | 1820804687929016320 |
| adam_text | IMAGE 1
CONTENTS
PREFACE X I X
BIOGRAPHY X X I LIST OF CONTRIBUTORS X X I I I
1 INTRODUCTION TO MARINE ACTINOBACTERIA 1
PANCHANATHAN MANIVASAGAN, JAYACHANDRAN VENKATESAN, AND SE-KWON KIM 1.1
INTRODUCTION 1
1.2 ACTINOBACTERIA 2
1.3 ORIGIN AND DISTRIBUTION OF MARINE ACTINOBACTERIA 2 1.4 ISOLATION AND
IDENTIFICATION OF MARINE ACTINOBACTERIA 3 1.5 INDIGENOUS MARINE
ACTINOBACTERIA 4 1.$ ROLE OF ACTINOBACTERIA IN THE MARINE ENVIRONMENT 5
1.7 IMPORTANCE OF MARINE ACTINOBACTERIA 5 1.7.1 ANTIBIOTICS 5
1.7.2 MELANINS 6
1.7.3 ENZYMES 6
1.7.3.1 A-AMYLASE 6
1.7.3.2 PROTEASES 7
1.7.3.3 CELLULASES 7
1.7.3.4 CHITINASE 8
1.7.3.5 KERATINASE 8
1.7.3.6 XYLANASES 9
1.7.4 ENZYME INHIBITORS 9
1.7.5 ANTICANCER COMPOUNDS 9 1.8 SYMBIOSES 10
1.9 BIOINFORMATICS 11
1.10 CONCLUSIONS 11
REFERENCES 12
HTTP://D-NB.INFO/1029120641
IMAGE 2
V I I CONTENTS
2 TREASURE HUNTING FOR USEFUL MICROORGANISMS IN THE MARINE
ENVIRONMENT 21 CHIAKI IMADA
2.1 INTRODUCTION 21
2.2 MICROORGANISMS LIVING IN THE MARINE ENVIRONMENT 21 2.2.1 PROTEASE
INHIBITOR PRODUCED BY MARINE BACTERIUM 21 2.2.2 CHITINASE INHIBITOR
PRODUCED BY MARINE BACTERIUM 22 2.2.3 ANTIBIOTICS PRODUCED BY MARINE
BACTERIA 23 2.2.4 ANTIBIOTICS PRODUCED BY MARINE ACTINOMYCETES 24 2.2.5
ANTIBIOTIC PRODUCED BY MARINE FUNGI 25
2.2.6 TYROSINASE INHIBITOR PRODUCED BY MARINE FUNGI 26 2.3
MICROORGANISMS LIVING IN DEEP SEA WATER 26 2.3.1 ISOLATION AND
INCUBATION OF LACTIC ACID BACTERIA FROM DEEP SEA WATER 28
REFERENCES 30
3 STRATEGY OF MARINE VIRUSES IN GLOBAL ECOSYSTEM 33 AMARDEEP SINGH,
MANOJ TRIVEDI, PRANJAL CHANDRA, AND RAJENDRA N. COYAL 3.1 INTRODUCTION
33
3.2 REPRODUCTIVE STRATEGIES OF VIRUSES 33 3.2.1 LYTIC INFECTION 34
3.2.2 CHRONIC INFECTION 34
3.2.3 LYSOGENY INFECTION 34 3.3 ABUNDANCE OF MARINE VIRUSES 35
3.4 VIRAL ACTIVITIES IN ECOSYSTEMS 36 3.4.1 DIVERSITY REGULATION 36
3.4.2 RATE OF RESISTANCE 37
3.4.3 LYSOGENY 39
3.4.4 THE EXCHANGE OF GENETIC MATERIAL 39 3.5 RECENT ADVANCEMENT OF
VIRUSES VERSUS DISEASES 40 3.6 THE EFFECT OF OCEAN ACIDIFICATION ON
MARINE VIRUSES 41 3.7 FURTHER ASPECTS 41
ACKNOWLEDGMENTS 41 REFERENCES 42
4 TAXONOMIC STUDY OF ANTIBIOTIC-PRODUCING MARINE ACTINOBACTERIA 45
PRIYANKA KISHORE, NEELAM MANGUTANI, HIRAK R. DASH, AND SURAJIT DAS 4.1
INTRODUCTION 45
4.2 MATERIALS AND METHODS 48
4.2.1 STUDY AREA AND SAMPLING 48 4.2.2 ISOLATION OF ACTINOMYCETES 48
4.2.3 SCREENING FOR ANTIMICROBIAL ACTIVITY 48
4.2.4 IDENTIFICATION AND SYSTEMATICS 49 4.2.4.1 PHENOTYPIC
CHARACTERIZATION 49 4.2.4.2 PHYSIOLOGICAL AND BIOCHEMICAL
CHARACTERIZATION 49
IMAGE 3
CONTENTS IVII
4.2.4.3 CHEMOTAXONOMICAL CHARACTERIZATION 50
4.3 RESULT 50
4.4 DISCUSSION 53
4.5 CONCLUSION 55
ACKNOWLEDGMENTS 55 REFERENCES 55
5 MARINE CYANOBACTERIA: A PROLIFIC SOURCE OF BIOACTIVE NATURAL PRODUCTS
AS DRUG LEADS 59 LIK TONG TAN 5.1 INTRODUCTION 59
5.2 BIOACTIVE SECONDARY METABOLITES FROM MARINE CYANOBACTERIA 60 5.2.1
ANTICANCER AGENTS 60
5.2.1.1 MICROTUBULE-INTERFERING COMPOUNDS 60 5.2.1.2 ACTIN-STABILIZING
AGENTS 61 5.2.1.3 HISTONE DEACETYLASE INHIBITORS 62 5.2.1.4 P53/MDM2
INHIBITOR 63
5.2.1.5 PROTEASOME INHIBITORS 64 5.2.1.6 PROTEASE INHIBITORS 65 5.2.1.7
APOPTOSIS-INDUCING AGENTS 67 5.2.1.8 OTHER POTENT CYTOTOXIC COMPOUNDS 68
5.2.2 NEUROMODULATING AGENTS 70 5.2.3 MODULATORS OF THE VOLTAGE-GATED
SODIUM CHANNELS AND CALCIUM OSCILLATION 71 5.2.4 CANNABINOMIMETIC AGENTS
74
5.2.5 ANTI-INFECTIVE AGENTS 74 5.2.5.1 ANTIPROTOZOAL AGENTS 74 5.2.5.2
ANTIMYCOBACTERIAL AGENTS 77 5.2.5.3 ANTI-INFLAMMATORY AGENTS 77
5.3 CONCLUSIONS 78
ACKNOWLEDGMENT 78 REFERENCES 78
6 MARINE BACTERIA ARE AN ATTRACTIVE SOURCE TO OVERCOME THE PROBLEMS OF
ANTIBIOTIC-RESISTANT STAPHYLOCOCCUS AUREUS 83 DAE-SUNG LEE, SUNG-HWAN
EOM, MYUNG-SUK LEE, AND YOUNG-MOG KIM 6.1 INTRODUCTION 83
6.1.1 MECHANISMS OF BACTERIAL RESISTANCE TO ANTIBIOTICS 83 6.1.2
PREVALENCE OF MRS A 84 6.2 STRATEGIES FOR OVERCOMING ANTIBIOTIC
RESISTANCE OF BACTERIA 86 6.2.1 SYNTHESIS OF NEW CHEMICAL ENTITIES 86 .
6.2.2 SCREENING NCES FOR NEW ANTIBIOTICS 87 6.2.3 SYNERGISTIC EFFECT OF
COMBINATION OF COMMERCIAL ANTIBIOTICS 87 6.2.4 THE GENOMICS REVOLUTION
87 6.2.5 BACTERIOPHAGES 88
IMAGE 4
V I I I | CONTENTS
6.2.6 MARINE BACTERIA PRODUCING AN ANTIBACTERIAL SUBSTANCE 88
6.3 MARINE BACTERIA ARE ATTRACTIVE NATURAL SOURCES FOR OVERCOMING
ANTIBIOTIC RESISTANCE OF MRS A 89 6.3.1 ISOLATION OF AN ANTI-MRSA
SUBSTANCE FROM MARINE BACTERIA 89 6.3.2 ANTIBACTERIAL ACTIVITY OF
1-ACETYL-P-CARBOLINE 90 6.3.3 COMBINATION EFFECT OF 1-ACETYL-P-CARBOLINE
AND P-LACTAMS AGAINST
MRSA 91 REFERENCES 93
7 MARINE BACTERIA AS PROBIOTICS AND THEIR APPLICATIONS IN AQUACULTURE 97
CHAMILANI NIKAPITIYA 7.1 INTRODUCTION 97
7.2 DEFINITION OF PROBIOTICS IN AQUACULTURE 99 7.3 SELECTING AND
DEVELOPING PROBIOTICS IN AQUACULTURE 101 7.4 EFFECTS OF PROBIOTICS ON
AQUATIC ORGANISMS 103 7.4.1 POSSIBLE MODE OF ACTION 103
7.4.1.1 COMPETITIVE EXCLUSION 103 7.4.1.2 ANTAGONISMS 104 7.4.1.3
PROBIOTICS AS IMMUNE STIMULANTS 104 7.4.1.4 ANTIVIRAL EFFECTS 106
7.4.1.5 DIGESTIVE PROCESS 106 7.4.1.6 ADHESION 107
7.5 PROBIOTICS IN THE LARVICULTURE 108
7.5.1 PROBIOTICS IN THE LARVICULTURE OF MOLLUSKS 108 7.5.2 PROBIOTICS IN
THE LARVICULTURE OF CRUSTACEANS 110 7.5.3 PROBIOTICS IN THE LARVICULTURE
OF FINFISH 112 7.5.3.1 PROBIOTICS IN FISH JUVENILE AND ADULTS 114
7.6 PROBLEMS ASSOCIATED WITH PROBIOTICS DEVELOPMENT 115 7.7 FURTHER WORK
AND CONCLUSIONS 116
REFERENCES 117
8 SMALL-MOLECULE ANTIBIOTICS FROM MARINE BACTERIA AND STRATEGIES TO
PREVENT REDISCOVERY OF KNOWN COMPOUNDS 127 MATTHIAS WIETZ, MARIA
MANSSON, NIKOLAJ C. VYNNE, AND LONE CRAM 8.1 ANTIBIOTIC ACTIVITY OF
MARINE BACTERIA 127 8.2 STRUCTURALLY ELUCIDATED MARINE BACTERIAL
ANTIBIOTICS 128 8.2.1 ACTINOBACTERIA 128
8.2.2 PSEUDOALTEROMCMAS SPP. 131 8.2.3 VIBRIONACEAE 132
8.2.4 ANTIBIOTIC COMPOUNDS FROM OTHER PHYLOGENETIC GROUPS 134 8.2.4.1
FIRMICUTES 134
8.2.4.2 ROSEOBACTER CLADE 135 8.2.4.3 PSEUDOMONAS SPP. 136 8.2.4.4
CYANOBACTERIA 136 8.3 COSMOPOLITAN ANTIBIOTICS: THE REDISCOVERY PROBLEM
138
IMAGE 5
CONTENTS I I X
8.4 FUTURE STRATEGIES FOR THE DISCOVERY OF MARINE BACTERIAL ANTIBIOTICS
139
8.4.1 ACCESSING NOVEL MARINE BACTERIAL NATURAL PRODUCTS THROUGH IMPROVED
CULTIVATION AND SAMPLING APPROACHES 140 8.4.2 ELICITING PRODUCTION OF
ANTIBIOTICS BY ACTIVATING SILENT BIOSYNTHETIC PATHWAYS 141 8.4.3
GENOME-BASED NATURAL PRODUCT RESEARCH 142
8.5 CONCLUSIONS AND PERSPECTIVES 143 REFERENCES 143
9 MARINE BACTERIOPHAGES FOR THE BIOCONTROL OF FISH AND SHELLFISH
DISEASES 161 MAHANAMA DE ZOYSA 9.1 INTRODUCTION 161
9.2 MODE OF ACTION OF PHAGES 162
9.3 DIVERSITY OF MARINE PHAGES 163
9.4 APPLICATION OF MARINE PHAGES TO CONTROL FISH AND SHELLFISH DISEASES
165 9.5 POTENTIALS AND LIMITATIONS OF PHAGE THERAPY IN MARINE FISH AND
SHELLFISH 167
ACKNOWLEDGMENT 169 REFERENCES 169
MARINE ACTINOMYCETES AS SOURCE OF PHARMACEUTICALLY IMPORTANT COMPOUNDS
173 M. L ARVINDA SWAMY INTRODUCTION 173
MARINE ACTINOMYCETES AS SOURCE OF THERAPEUTICS 173 MARINE ACTINOMYCETE
COMPOUNDS AS ANTIBACTERIALS 174 MARINE ACTINOMYCETE COMPOUNDS AS
ANTITUMORS/ ANTIPROLIFERATIVE 177 MARINE ACTINOMYCETE ENZYMES AS
ANTIPROLIFERATIVES 181
MARINE ACTINOMYCETE COMPOUNDS AS ANTIMALARIALS 182 MARINE ACTINOMYCETE
COMPOUNDS AS ANTIFUNGALS 184 BIOACTIVE COMPOUNDS FROM SPONGE-ASSOCIATED
ACTINOMYCETES 184 CONCLUSION 187 ACKNOWLEDGMENT 187
REFERENCES 187
11 ANTIMICROBIAL AGENTS FROM MARINE CYANOBACTERIA AND ACTI NOMYCETES 191
ARNAB PRAMANIK, MALAY SAHA, AND BARINDRA SANA 11.1 INTRODUCTION 191
11.2 ANTIMICROBIALS FROM MARINE ACTINOMYCETES 192 11.2.1 ANTIBACTERIAL
ACTIVITY 192 11.2.2 ANTIFUNGAL ACTIVITY 194
10
10.1 10.2 10.3 10.4
10.5 10.6 10.7 10.8 10.9
IMAGE 6
X | CONTENTS
11.2.3 ANTIVIRAL ACTIVITY 195
11.3 ANTIMICROBIALS FROM MARINE CYANOBACTERIA 196 11.3.1 ANTIBACTERIAL
ACTIVITY 196 11.3.2 ANTIFUNGAL ACTIVITY 197 11.3.3 ANTIVIRAL ACTIVITY
198
11.4 CURRENT RESEARCH STATUS: CHALLENGES AND FUTURE PROSPECTS 199 11.5
CONCLUSIONS 201
REFERENCES 201
12 BIOACTIVE COMPOUNDS FROM MARINE ACTINOMYCETES 207 ANA M.
INIGUEZ-MARTINEZ, GRACIELA GUERRA-RIVAS, NAHARA E. AYALA-SANCHEZ, AND
IRMA E. SORIA-MERCADO 12.1 INTRODUCTION 207
12.2 ACTINOMYCETES 207
12.3 DIVERSITY AND DISTRIBUTION OF MARINE ACTINOBACTERIA 208 12.4
BIOACTIVE COMPOUNDS 210 12.5 CONCLUSIONS 217
ACKNOWLEDGMENT 217 REFERENCES 217
13 FUNGAL BIOACTIVE GENE CLUSTERS: A MOLECULAR INSIGHT 223 IRA
BHATNAGAR AND SE-KWON KIM 13.1 INTRODUCTION TO FUNGAL SECONDARY
METABOLITES 223 13.2 POLYKETIDE SYNTHASE 225
13.2.1 CLASSIFICATION OF FUNGAL PKS 226 13.2.1.1 NONREDUCING PKSS 227
13.2.1.2 PARTIALLY REDUCING PKSS 228 13.2.1.3 HIGHLY REDUCING PKSS 229
13.3 NONRIBOSOMAL PEPTIDE SYNTHETASE 229 13.4 PKS AND NRPS PRODUCTS 231
13.4.1 FUNGAL PKS PRODUCTS: AFLATOXIN AND FUSARIN 231 13.4.2 FUNGAL NRPS
PRODUCTS: PENICILLIN/CEPHALOSPORIN AND DIKETOPIPERAZINE 232 13.5
CONCLUSIONS 233
ACKNOWLEDGMENTS 233 REFERENCES 234
14 ANTICANCER POTENTIALS OF MARINE-DERIVED FUNGAL METABOLITES 237
SE-KWON KIM AND PRADEEP DEWAPRIYA 14.1 INTRODUCTION 237
14.2 MARINE FUNGI 238
14.3 CANCER INITIATION, PROGRESSION, AND THERAPEUTICS 238 14.4
ANTICANCER METABOLITES OF MARINE FUNGAL ORIGIN 239 14.4.1 CYTOTOXIC AND
ANTITUMOR COMPOUNDS 239 14.4.2 APOPTOSIS INDUCING METABOLITES 241
IMAGE 7
CONTENTS IXI
14.4.3 ANTIMETASTASIS COMPOUNDS 241
14.4.4 ANTI-INFLAMMATORY AND ANTIOXIDANT COMPOUNDS 242 14.5 FUTURE
PROSPECTS AND CONCLUDING REMARKS 243 REFERENCES 243
15 ANTIFUNGAL AND ANTIMYCOTOXIN ACTIVITIES OF MARINE ACTINOMYCETES AND
THEIR COMPOUNDS 247 PEI-SHENG YAN, LI-XIN CAO, ANDJING REN
15.1 INTRODUCTION 249
15.2 DIVERSITY OF ACTINOMYCETES IN THE SEA 247 15.2.1 FREE-LIVING MARINE
ACTINOMYCETES 247 15.2.2 ORGANISMS-ASSOCIATED MARINE ACTINOMYCETES 249
15.3 DIVERSITY OF NATURAL COMPOUNDS FROM MARINE ACTINOMYCETES 250
15.3.1 AMINOGLYCOSIDES 251 15.3.2 MACROLIDES 251
15.3.3 POLYKETIDES 251
15.3.4 ENZYMES AND PROTEINS 251 15.3.5 OTHER SUBSTANCES 252 15.4
BIOLOGICAL ACTIVITIES 252 15.4.1 ANTIFUNGAL ACTIVITIES AGAINST CLINICAL
AND HUMAN
PATHOGENS 252
15.4.2 ANTIFUNGAL ACTIVITIES AGAINST PLANT FUNGAL PATHOGENS 253 15.4.3
ANTIMYCOTOXIN ACTIVITIES 255 15.5 CONCLUSIONS 256 _
ACKNOWLEDGMENTS 256 REFERENCES 256
16 ANTITUBERCULOSIS MATERIALS FROM MARINE MICROBES 261 QUANG VAN TA AND
SE-KWON KIM 16.1 INTRODUCTION 261
16.2 MARINE MICROBE-DERIVED ANTITUBERCULOSIS AGENTS 262 16.2.1 ALKALOIDS
262
16.2.2 LIPIDS 263
16.2.3 PEPTIDES 263
16.2.4 TERPENES 264
16.3 CONCLUSIONS 264
REFERENCES 265
17 HARNESSING THE CHEMICAL AND GENETIC DIVERSITIES OF MARINE
MICROORGANISMS FOR MEDICAL APPLICATIONS 267 XINQING ZHAO, WENCE JIAO,
AND XIAONA XU
17.1 INTRODUCTION 267
17.2 NOVEL MNPS 268
17.3 GENE-BASED STUDIES OF MNPS 279 17.4 MNPS DISCOVERY USING GENOME
MINING 281
IMAGE 8
X I I | CONTENTS
17.4.1 GENOME MINING OF PEPTIDE PRODUCTS USING MALDI-TOF MASS
SPECTROMETRY-BASED APPROACHES 284 17.4.2 COMPARATIVE METABOLIC PROFILING
FOR THE DISCOVERY OF NOVEL COMPOUNDS 285 17.4.3 IDENTIFICATION OF THE
BIOSYNTHETIC GENES BY SINGLE-CELL GENOME
AMPLIFICATION 286
17.5 CONCLUSION AND PROSPECTS 286 ACKNOWLEDGMENTS 287 REFERENCES 287
18 MARINE SYMBIOTIC MICROORGANISMS: A NEW DIMENSION IN NATURAL PRODUCT
RESEARCH 295 S.W.A HIMAYA AND SE-KWON KIM 18.1 INTRODUCTION 295
18.2 MARINE MICROORGANISMS AND THEIR SYMBIOTIC RELATIONSHIPS 296 18.3
BIOLOGICALLY ACTIVE METABOLITES OF MARINE SYMBIOTIC MICROBES 297 18.3.1
MICROORGANISMS ISOLATED FROM MARINE ALGAE 298 18.3.2 MARINE
SPONGE-ASSOCIATED MICROORGANISM 299
18.3.3 MARINE INVERTEBRATE-ASSOCIATED MICROORGANISMS 301 18.3.4
MICROBIAL ASSOCIATION WITH MANGROVE 302 18.4 CONCLUDING REMARKS 303
REFERENCES 303
19 APPLICATION OF PROBIOTICS FROM MARINE MICROBES FOR SUSTAINABLE MARINE
AQUACULTURE DEVELOPMENT 307 NGUYEN VAN DUY, LE MINH HOANG, AND TRANG SY
TRUNG 19.1 INTRODUCTION 307
19.1.1 THE CONCEPT OF SUSTAINABLE DEVELOPMENT IN AQUACULTURE 307 19.1.2
FRESHWATER AND MARINE CULTURE FOR A SUSTAINABLE DEVELOPMENT 308 19.1.3
CURRENT APPROACHES FOR SUSTAINABLE MARINE AQUACULTURE DEVELOPMENT 308
19.1.3.1 VACCINE 308
19.1.3.2 ANTIBIOTIC ALTERNATIVES 309 19.1.3.3 PREBIOTICS 309 19.1.3.4
PROBIOTICS 310 19.2 THE APPLICATION OF PROBIOTICS FOR MARINE FISHES 310
19.2.1 TURBOT (SCOPHTHALMUS MAXIMUS) 310 19.2.2 ATLANTIC COD (GADUS
MORHUA) 313 19.2.3 RAINBOW TROUT (ONCORHYNCHUS MY KISS) 315 19.2.4
GILTHEAD SEA BREAM ( SPARUS AURATU) 321 19.2.5 OTHER MARINE FISHES 323
19.2.5.1 SEA BASS (DICENTRARCHUS LAB RAX) 323
19.2.5.2 ATLANTIC HALIBUT ( HIPPOGLOSSUS HIPPOGLOSSUS) 324 19.2.5.3
OLIVE FLOUNDER (PARALICHTHYS OLIVACEUS) 324 19.2.5.4 CLOWNFISH
(AMPHIPRION SPP.) 325
19.2.5.5 COMMON SNOOK (CENTROPOMUS UNDECIMALIS) 325
IMAGE 9
19.2.5.6 POLLACK ( POLLACHIUS POLLACHIUS) 326
19.2.5.7 GOLDFISH ( CARASSIUS AURATUS) 326 19.3 THE APPLICATION OF
PROBIOTICS FOR MARINE CRUSTACEANS 326 19.3.1 BLACK TIGER SHRIMP {PENAEUS
MONODON) 326 19.3.2 WHITE SHRIMP (L. VANNAMEI) 329 19.3.3 OTHER
CRUSTACEANS 334 19.3.3.1 BLUE SHRIMP (LITOPENAEUS STYLIROSTRIS) 334
19.3.3.2 WESTERN KING PRAWN ( PENAEUS LATISULCATUS) 334 19.3.3.3 -
TROPICAL ROCK LOBSTER ( PANULIRUS ORNATUS) 334 19.3.3.4 CRABS 335 19.4
THE APPLICATION OF PROBIOTICS FOR MARINE MOLLUSKS 335 19.4.1 CHILEAN
SCALLOP (A. PURPURATUS) 336 19.4.2 PACIFIC OYSTER (C. GIG AS) 339 19.4.3
OTHER MOLLUSKS 339 19.4.3.1 GREAT SCALLOP ( P . M A X I M U S ) 3 3 9
19.4.3.2 EUROPEAN FLAT OYSTER (O. EDULIS) 340 19.4.3.3 CORTEZ OYSTER (C.
CORTEZIENSIS) 340
REFERENCES 340
20 ANTIMICROBIAL PROPERTIES OF EICOSAPENTAENOIC ACID (C20: 5N-3) ANDREW
P. DESBOIS 20.1 INTRODUCTION 351
20.1.1 POTENTIAL OF EICOSAPENTAENOIC ACID AS AN ANTIMICROBIAL AGENT 351
20.1.2 BIOCHEMISTRY, BIOLOGICAL FUNCTIONS, AND NATURAL SOURCES 351 20.2
SPECTRUM OF ANTIMICROBIAL ACTIVITY AND POTENCY 355 20.2.1 ISOLATION AND
CONFIRMATION OF ANTIMICROBIAL ACTIVITY 355 20.2.2 ANTIBACTERIAL
ACTIVITIES 355 20.2.3 ANTIFUNGAL ACTIVITIES 357 20.2.4 ANTAGONISTIC
ACTIVITIES AGAINST MICROALGAE 357
20.2.5 ANTAGONISTIC ACTIVITIES AGAINST PROTOZOA AND VIRUSES 358 20.3
STRUCTURE RELATIONSHIP WITH ACTIVITY 358 20.3.1 IMPORTANCE OF A FREE
CARBOXYL GROUP 358 20.3.2 IMPORTANCE OF UNSATURATED DOUBLE BONDS 359
20.4 MECHANISM OF ANTIMICROBIAL ACTION 359 20.4.1 MICROBIAL GROWTH
INHIBITION AND CELL KILLING 359 20.4.2 EFFECTS ON THE CELL MEMBRANE 360
20.4.3 EFFECTS ON OTHER CELL TARGETS 361
20.5 SAFETY, DELIVERY, AND BIOTECHNOLOGICAL APPLICATION 361 20.5.1
TOXICITY IN VITRO 361 20.5.2 TOXICITY IN VIVO 362 20.5.3 DELIVERY AND
BIOTECHNOLOGICAL EXPLOITATION 362
20.6 CONCLUDING REMARKS 363
ABBREVIATIONS 364 ACKNOWLEDGMENT 364 REFERENCES 365
IMAGE 10
X I V | CONTENTS
21 BIOPROSPECTING OF MARINE MICROBIAL SYMBIONTS: EXPLOITATION OF
UNDEREXPLORED MARINE MICROORGANISMS 369 OCKY K. RADJASA 21.1
INTRODUCTION 369
21.2 MARINE MICROBIAL SYMBIONTS 370 21.3 BIOETHICAL AND SUPPLY ISSUES IN
UTILIZING MARINE INVERTEBRATES 371 21.4 MARINE FUNGAL SYMBIONTS OF
CORALS AS SUSTAINABLE SOURCES OF MARINE
NATURAL PRODUCTS 372 21.5 MARINE ACTINOMYCETE SYMBIONTS AS PROLIFIC
MARINE NATURAL PRODUCTS 373 21.6 NEW AVENUE OF RESEARCH: MARINE NATURAL
PRODUCTS FROM FUNGAL
SYMBIONTS OF CORALS 375 21.7 CONCLUDING REMARKS 376
REFERENCES 377
22 MARINE MICROORGANISMS AND THEIR VERSATILE APPLICATIONS IN BIOACTIVE
COMPOUNDS 379 SOUGATA JANA, ARIJIT GANDHI, SAMRAT CHAK RABORTY, KALYAN
K. SEN, AND SANAT K. BASU 22.1 INTRODUCTION 379
22.2 SEPARATION AND ISOLATION TECHNIQUES OF BIOACTIVE COMPOUNDS FROM
MARINE ORGANISMS 379 22.3 DIFFERENT BIOACTIVE COMPOUNDS FROM MARINE
ORGANISMS 380 22.3.1 BIOEMULSIFIERS AND BIOSURFACTANTS 380 22.3.2
BIOACTIVE METABOLITES OFTHERAPEUTIC VALUE 381 22.3.3 ENZYMES 382
22.3.3.1 PROTEASE 383 22.3.3.2 LIPASES 383 22.3.3.3 CHITINASE 384
22.3.3.4 ALGINATE LYASES 384
22.3.3.5 AGARASE 384 22.4 POLYSACCHARIDES 384
22.5 PIGMENTS 386
22.6 CONCLUSIONS 386
REFERENCES 387
23 METABOLITES OF MARINE MICROORGANISMS AND THEIR PHARMACOLOGICAL
ACTIVITIES 393 KUSTIARIYAH TARMAN, ULRIKE LINDEQUIST, AND SABINE MUNDT
23.1 INTRODUCTION 393
23.2 MARINE FUNGI 393
23.2.1 BIOLOGICAL SOURCES OF MARINE FUNGI 394 23.2.2 MARINE FUNGAL
METABOLITES AND THEIR PHARMACOLOGICAL ACTIVITIES 395 23.2.3 RECENT FOCUS
ON MARINE FUNGAL RESEARCH 395
IMAGE 11
CONTENTS |XV
23.3 MARINE ACTINOMYCETES 397 23.3.1 BIOLOGICAL SOURCES OF MARINE
ACTINOMYCETES 398 23.3.2 METABOLITES OF MARINE ACTINOMYCETES AND THEIR
PHARMACOLOGICAL ACTIVITIES 398
23.3.3 RECENT FOCUS ON MARINE ACTINOMYCETE RESEARCH 401 23.4 MARINE
CYANOBACTERIA 402 23.4.1 BIOLOGICAL SOURCES OF MARINE CYANOBACTERIA 402
23.4.2 METABOLITES OF MARINE CYANOBACTERIA AND THEIR PHARMACOLOGICAL
ACTIVITIES 402
23.4.3 RECENT FOCUS OF RESEARCH ON MARINE CYANOBACTERIA 404 23.5
CONCLUSIONS 407
REFERENCES 407
24 SPONGES: A RESERVOIR FOR MICROORGANISM-DERIVED BIOACTIVE METABOLITES
417 VISAMSETTI AMARENDRA, RAMACHANDRAN 5. SANTHOSH, AND KANDASAMY
DHEVENDARAN 24.1 INTRODUCTION 417
24.2 COLLECTION OF SPONGES AND ASSOCIATED MICROBES 420 24.2.1
IDENTIFICATION OF SPONGES AND EXTRACTION OF MICROBES 420 24.2.2
ISOLATION OF MICROBES 421
24.2.3 EXTRACTION OF METABOLITES 421 24.2.4 CHARACTERIZATION OF
BIOLOGICALLY ACTIVE COMPOUND 421 24.3 BACTERIA .421
24.3.1 ACTINOBACTERIA 422 24.3.2 FIRMICUTES 424
24.3.3 PROTEOBACTERIA 425 24.3.3.1 ALPHAPROTEOBACTERIA 426 24.3.3.2
BETAPROTEOBACTERIA 426 24.3.3.3 GAMMAPROTEOBACTERIA 426 24.3.3.4
DELTAPROTEOBACTERIA 428 24.3.4 VERRUCOMICROBIA 428 24.3.5 CYANOBACTERIA
428 24.4 UNIDENTIFIED BACTERIA 429 24.5 FUNGI 430
24.5.1 ASCOMYCETES 430 24.5.2 DOTHIDEOMYCETES 431 24.5.3 EUROTIOMYCETES
433 24.5.4 SORDARIOMYCETES 437 24.6 UNIDENTIFIED FUNGAL STRAINS FROM
SPONGES 440 24.7 COMPOUNDS IN CLINICAL TRIAL AND USE 440 24.8
CONCLUSIONS 447
ACKNOWLEDGMENTS 447 REFERENCES 447
IMAGE 12
X V I I CONTENTS
25 BIOACTIVE MARINE MICROORGANISMS FOR BIOCATALYTIC REACTIONS
IN ORGANIC COMPOUNDS 453 LENILSON C. ROCHA, JULIETA R. DE OLIVEIRA,
BRUNA VACONDIO, CISELE N. RODRIGUES, MIMA H. REGALI SELEGHIM, AND ANDRE
L. MELEIRO PORTO 25.1 INTRODUCTION 453
25.2 MARINE ENZYMES 454
25.3 BIOTRANSFORMATION OF NATURAL PRODUCTS BY MARINE BIOCATALYSTS 455
25.4 BIODEGRADATION OF ORGANIC COMPOUNDS BY MARINE BIOCATALYSTS 459 25.5
REDUCTION OF CARBONYL GROUPS (KETONES AND KETO ESTERS) BY MARINE
BIOCATALYSTS 466
25.6 HYDROLYSIS OF EPOXIDES BY MARINE BIOCATALYSTS 471 25.7 COLLECTION
AND ISOLATION OF BIOACTIVE MARINE MICROORGANISMS 474 25.7.1 FUNGI 477
25.7.2 BACTERIA 479
25.7.3 ACTINOMYCETES 480 25.7.4 BACTERIAL EXTREMOPHILES 482 25.8
CONCLUSIONS AND PERSPECTIVES 483 REFERENCES 484
26 MARINE MICROBIAL ENZYMES: BIOTECHNOLOGICAL AND BIOMEDICAL ASPECTS 491
BARINDRA SANA 26.1 INTRODUCTION. 491
26.2 EXTREMOZYMES: MOST POTENTIAL MARINE ENZYMES 492 26.3
BIOTECHNOLOGICAL ASPECTS 494 26.3.1 DETERGENT INDUSTRY 494 26.3.2 FOOD
PROCESSING INDUSTRY 495 26.3.3 CHEMICAL AND PHARMACEUTICAL SYNTHESIS 496
26.3.4 BIOTECHNOLOGICAL RESEARCH 498
26.3.5 LEATHER INDUSTRY 498 26.3.6 PAPER INDUSTRY 499
26.3.7 TEXTILE INDUSTRY 499 26.3.8 BIOFUEL INDUSTRY 500 26.3.9
BIOREMEDIATION AND BIOFOULING 501 26.4 BIOMEDICAL ASPECTS 502
26.5 CONCLUDING REMARKS AND PERSPECTIVES 503 REFERENCES 504
27 BIOMEDICAL APPLICATIONS OF MYCOSPORINE-LIKE AMINO ACIDS 509 RICHA AND
RAJESHWAR P. SINHA 27.1 INTRODUCTION 509
27.2 MYCOSPORINE-LIKE AMINO ACIDS (MAAS) 510 27.3 DISTRIBUTION OF MAAS
514
27.3.1 MAAS IN CYANOBACTERIA 514
IMAGE 13
27.3.2 MAAS IN MACROALGAE 515
27.3.3 MAAS IN MICROALGAE 516 27.3.3.1 DINOFLAGELLATES 516 27.3.3.2
PRYMNESIOPHYTES 517 27.3.3.3 RAPHIDOPHYTES 517 27.3.3.4 DIATOMS 517
27.3.4 MAAS IN LOWER INVERTEBRATES 518
27.4 GENETIC CONTROL OF MAAS SYNTHESIS 519 27.5- MAAS INDUCTION 521
27.6 BIOMEDICAL POTENTIALS OF MAAS 522 27.7 MAAS AS PHOTOPROTECTANTS 523
27.8 MAAS AS AN ANTIOXIDANT 524 27.9 MAAS AS BLOCKER OF DIMER FORMATION
525 27.10 MAAS AS AN OSMOREGULATOR 525 27.11 CONCLUSIONS AND FUTURE
PROSPECTS 526
ACKNOWLEDGMENT 526 REFERENCES 526
INDEX 535
|
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| dewey-raw | 547.7 |
| dewey-search | 547.7 |
| dewey-sort | 3547.7 |
| dewey-tens | 540 - Chemistry and allied sciences |
| discipline | Chemie / Pharmazie Biologie |
| format | Book |
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| id | DE-604.BV041280456 |
| illustrated | Illustrated |
| indexdate | 2024-12-24T03:37:47Z |
| institution | BVB |
| isbn | 9783527333271 3527333274 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-026253898 |
| oclc_num | 858078273 |
| open_access_boolean | |
| owner | DE-91G DE-BY-TUM |
| owner_facet | DE-91G DE-BY-TUM |
| physical | XXIX, 549 S. Ill., graph. Darst. 25 cm |
| publishDate | 2013 |
| publishDateSearch | 2013 |
| publishDateSort | 2013 |
| publisher | Wiley-VCH-Verl. |
| record_format | marc |
| spellingShingle | Marine microbiology bioactive compounds and biotechnological applications Bioaktive Verbindungen (DE-588)4145589-7 gnd Meeresmikrobiologie (DE-588)4747276-5 gnd Industrielle Mikrobiologie (DE-588)4026845-7 gnd |
| subject_GND | (DE-588)4145589-7 (DE-588)4747276-5 (DE-588)4026845-7 |
| title | Marine microbiology bioactive compounds and biotechnological applications |
| title_auth | Marine microbiology bioactive compounds and biotechnological applications |
| title_exact_search | Marine microbiology bioactive compounds and biotechnological applications |
| title_full | Marine microbiology bioactive compounds and biotechnological applications ed. by Se-Kwon Kim |
| title_fullStr | Marine microbiology bioactive compounds and biotechnological applications ed. by Se-Kwon Kim |
| title_full_unstemmed | Marine microbiology bioactive compounds and biotechnological applications ed. by Se-Kwon Kim |
| title_short | Marine microbiology |
| title_sort | marine microbiology bioactive compounds and biotechnological applications |
| title_sub | bioactive compounds and biotechnological applications |
| topic | Bioaktive Verbindungen (DE-588)4145589-7 gnd Meeresmikrobiologie (DE-588)4747276-5 gnd Industrielle Mikrobiologie (DE-588)4026845-7 gnd |
| topic_facet | Bioaktive Verbindungen Meeresmikrobiologie Industrielle Mikrobiologie |
| url | http://deposit.dnb.de/cgi-bin/dokserv?id=4216953&prov=M&dok_var=1&dok_ext=htm http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026253898&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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