Proteopathic seeds and neurodegenerative diseases
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| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Berlin [u.a.]
Springer
2013
|
| Schriftenreihe: | Research and perspectives in Alzheimer's disease
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
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| LEADER | 00000nam a2200000 c 4500 | ||
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| 007 | t| | ||
| 008 | 130412s2013 xx ad|| |||| 00||| eng d | ||
| 020 | |a 9783642354908 |9 978-3-642-35490-8 | ||
| 035 | |a (OCoLC)863645359 | ||
| 035 | |a (DE-599)BVBBV040943051 | ||
| 040 | |a DE-604 |b ger |e rakwb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 | ||
| 082 | 0 | 4 | |a 612.8 |2 23 |
| 084 | |a YG 4513 |0 (DE-625)153499:12919 |2 rvk | ||
| 245 | 1 | 0 | |a Proteopathic seeds and neurodegenerative diseases |c Mathias Jucker ..., ed. [Fondation IPSEN pour la Recherche Therapeutique] |
| 264 | 1 | |a Berlin [u.a.] |b Springer |c 2013 | |
| 300 | |a XI, 155 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Research and perspectives in Alzheimer's disease | |
| 650 | 4 | |a Medizin | |
| 650 | 4 | |a Medicine | |
| 650 | 4 | |a Neurosciences | |
| 650 | 4 | |a Toxicology | |
| 650 | 0 | 7 | |a Proteinfaltung |0 (DE-588)4324567-5 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Nervendegeneration |0 (DE-588)4300182-8 |2 gnd |9 rswk-swf |
| 655 | 7 | |8 1\p |0 (DE-588)1071861417 |a Konferenzschrift |y 2012 |z Paris |2 gnd-content | |
| 689 | 0 | 0 | |a Nervendegeneration |0 (DE-588)4300182-8 |D s |
| 689 | 0 | 1 | |a Proteinfaltung |0 (DE-588)4324567-5 |D s |
| 689 | 0 | |8 2\p |5 DE-604 | |
| 700 | 1 | |a Jucker, Mathias |e Sonstige |4 oth | |
| 776 | 0 | 8 | |i Erscheint auch als |n Online-Ausgabe |z 978-3-642-35491-5 |
| 856 | 4 | 2 | |m Digitalisierung UB Regensburg |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025921766&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 856 | 4 | 2 | |m Digitalisierung UB Regensburg |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025921766&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |3 Klappentext |
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| 883 | 1 | |8 2\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-025921766 | |
Datensatz im Suchindex
| _version_ | 1820163268848648192 |
|---|---|
| adam_text |
Contents
Widening Spectrum of
Prions
Causing
Neurodegenerative
Diseases
.,. 1
Stanley B. Prusiner
β-
Amyloid Fibril Structures, In Vitro and In Vivo
. 19
Robert Tycko
Structure-Activity Relationship of Amyloids
. 33
Jason Greenwald and Roland
Riek
Seeding and Cross-seeding in Amyloid Diseases
. 47
Per
Westermark
and
Gunilla T.
Westermark
The Prion-Like Aspect of Alzheimer Pathology
. 61
Sarah K. Fritschi, Bahareh Eftekharzadeh, Giusi
Manfredi,
Tsuyoshi
Hamaguchi,
Götz Heilbronner, Amudha Nagarathinam, Franziska Langer,
Yvonne
S. Eisele,
Lary
Walker, and
Mathias Jucker
Amyloid-ß Transmissibility. 71
С.
Duran-Aniotz, R.
Morales, I. Moreno-Gonzalez, and C.
Soto
Prion-Like Properties of Assembled
Tau
Protein
. 87
Florence Clavaguera,
Markus Tolnay,
and Michel Goedert
Accumulating Evidence Suggests that Parkinson's Disease
Is a Prion-Like Disorder
. 97
Nolwen L.
Rey,
Elodie Angot,
Christopher Dunning, Jennifer A.
Steiner,
and
Patrik
Brundin
Propagation and Replication of Misfolded
SODI:
Implications
for Amyotrophic Lateral Sclerosis
. 115
Anne Bertolotti
viii Contents
Development
of Drugs That Target Proteopathic Seeds Will
Require Measurement of Drug Mechanism in Human Brain
. 123
Peter T. Lansbury Jr
The Role of Functional
Prions
in the Persistence of Memory
Storage
. 131
Eric R. Kandel,
Irina
Derkatch, and
Elias Pavlopoulos
Index
. 153
Proteopathic
Seeds
and Neurodégenerative
Diseases]
|Thé misfolding
and aggregation of specific
proteins
isi
¡an early and obligatory event jn many of the age-relatedl
neurodégenerative
diseases of humans;; and appears
tof
occur; rhanyjyears before the onset of clinical symptoms!
¡The initial cause of this pathogenic cascade and thef
means whereby disease spreads through the
nervoušj
|system| remain uncertain^ A recent surge of research^
first instigated By pathologic similarities between prion|
disease and Alzheimer's disease^ has increasingly^
implicated corruptive protein templating^ or seedingTasi
a prime factor in the
neurodégenerative processViThe
prion-like corruption of proteins also characterizes such
clinically and etiologically diverse neurological disorders
as Parkinson's disease,
Huntington
's
disease^ amyql
{trophic jateral sclerosis, and
frontoţemporal
lobardege|
hëration^Understanding
the misfolding, aggregation^
trafficking and pathogenicity of affected proteins thus
[could reveal universal principles and common thera
peutic targets for some of the most devastating and
І
intractable human brain
disorders! |
| any_adam_object | 1 |
| building | Verbundindex |
| bvnumber | BV040943051 |
| classification_rvk | YG 4513 |
| ctrlnum | (OCoLC)863645359 (DE-599)BVBBV040943051 |
| dewey-full | 612.8 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 612 - Human physiology |
| dewey-raw | 612.8 |
| dewey-search | 612.8 |
| dewey-sort | 3612.8 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Book |
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| id | DE-604.BV040943051 |
| illustrated | Illustrated |
| indexdate | 2025-01-02T18:36:01Z |
| institution | BVB |
| isbn | 9783642354908 |
| language | English |
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| physical | XI, 155 S. Ill., graph. Darst. |
| publishDate | 2013 |
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| publisher | Springer |
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| series2 | Research and perspectives in Alzheimer's disease |
| spelling | Proteopathic seeds and neurodegenerative diseases Mathias Jucker ..., ed. [Fondation IPSEN pour la Recherche Therapeutique] Berlin [u.a.] Springer 2013 XI, 155 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Research and perspectives in Alzheimer's disease Medizin Medicine Neurosciences Toxicology Proteinfaltung (DE-588)4324567-5 gnd rswk-swf Nervendegeneration (DE-588)4300182-8 gnd rswk-swf 1\p (DE-588)1071861417 Konferenzschrift 2012 Paris gnd-content Nervendegeneration (DE-588)4300182-8 s Proteinfaltung (DE-588)4324567-5 s 2\p DE-604 Jucker, Mathias Sonstige oth Erscheint auch als Online-Ausgabe 978-3-642-35491-5 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025921766&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025921766&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Proteopathic seeds and neurodegenerative diseases Medizin Medicine Neurosciences Toxicology Proteinfaltung (DE-588)4324567-5 gnd Nervendegeneration (DE-588)4300182-8 gnd |
| subject_GND | (DE-588)4324567-5 (DE-588)4300182-8 (DE-588)1071861417 |
| title | Proteopathic seeds and neurodegenerative diseases |
| title_auth | Proteopathic seeds and neurodegenerative diseases |
| title_exact_search | Proteopathic seeds and neurodegenerative diseases |
| title_full | Proteopathic seeds and neurodegenerative diseases Mathias Jucker ..., ed. [Fondation IPSEN pour la Recherche Therapeutique] |
| title_fullStr | Proteopathic seeds and neurodegenerative diseases Mathias Jucker ..., ed. [Fondation IPSEN pour la Recherche Therapeutique] |
| title_full_unstemmed | Proteopathic seeds and neurodegenerative diseases Mathias Jucker ..., ed. [Fondation IPSEN pour la Recherche Therapeutique] |
| title_short | Proteopathic seeds and neurodegenerative diseases |
| title_sort | proteopathic seeds and neurodegenerative diseases |
| topic | Medizin Medicine Neurosciences Toxicology Proteinfaltung (DE-588)4324567-5 gnd Nervendegeneration (DE-588)4300182-8 gnd |
| topic_facet | Medizin Medicine Neurosciences Toxicology Proteinfaltung Nervendegeneration Konferenzschrift 2012 Paris |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025921766&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025921766&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT juckermathias proteopathicseedsandneurodegenerativediseases |