Nanomedicine infectious diseases, immunotherapy, diagnostics, antifibrotics, toxicology and gene medicine
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Elsevier, Acad. Press
2012
|
| Ausgabe: | 1. ed. |
| Schriftenreihe: | Methods in enzymology
509 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
MARC
| LEADER | 00000nam a2200000 cb4500 | ||
|---|---|---|---|
| 001 | BV040281235 | ||
| 003 | DE-604 | ||
| 005 | 20120809 | ||
| 007 | t| | ||
| 008 | 120628s2012 xx ad|| |||| 00||| eng d | ||
| 020 | |a 9780123918581 |c hbk |9 978-0-12-391858-1 | ||
| 035 | |a (OCoLC)801378060 | ||
| 035 | |a (DE-599)BVBBV040281235 | ||
| 040 | |a DE-604 |b ger |e rakwb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 |a DE-12 |a DE-19 | ||
| 084 | |a WC 4355 |0 (DE-625)148096: |2 rvk | ||
| 245 | 1 | 0 | |a Nanomedicine |b infectious diseases, immunotherapy, diagnostics, antifibrotics, toxicology and gene medicine |c ed. by Nejat Düzgüneş |
| 250 | |a 1. ed. | ||
| 264 | 1 | |a Amsterdam [u.a.] |b Elsevier, Acad. Press |c 2012 | |
| 300 | |a LIV, 408 S., [6] Bl. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Methods in enzymology |v 509 | |
| 650 | 0 | 7 | |a Medizin |0 (DE-588)4038243-6 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Nanotechnologie |0 (DE-588)4327470-5 |2 gnd |9 rswk-swf |
| 655 | 7 | |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
| 689 | 0 | 0 | |a Nanotechnologie |0 (DE-588)4327470-5 |D s |
| 689 | 0 | 1 | |a Medizin |0 (DE-588)4038243-6 |D s |
| 689 | 0 | |C b |5 DE-604 | |
| 700 | 1 | |a Düzgüneş, Nejat |e Sonstige |0 (DE-588)129612227 |4 oth | |
| 830 | 0 | |a Methods in enzymology |v 509 |w (DE-604)BV000000938 |9 509 | |
| 856 | 4 | 2 | |m Digitalisierung UB Regensburg |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025136589&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-025136589 | |
Datensatz im Suchindex
| _version_ | 1819628308515520512 |
|---|---|
| adam_text | Contents
Contributors
xiii
Preface
xxi
Volumes in Series
xxv
1.
Enhanced Antiviral Activity of Acyclovir Loaded into Nanoparticles
1
Roberta
Cavalli,
Manuela
Donalisio,
Agnese Bisazza,
Andrea Civra,
Elisabetta Ranucci, Paolo Ferruti, and David
Lembo
1.
Introduction
2
2.
Preparation of Acyclovir-Loaded Nanoparticles and Fluorescent
Nanoparticles
4
3.
Biocompatibility Assays
8
4.
Assessment of the Antiviral Activity
14
5.
Conclusions
18
Acknowledgements
18
References
18
2.
Gold manno-Glyconanoparticles for Intervening in
HIV
gpl20 Carbohydrate-Mediated Processes
21
Paolo
Di
Gianvincenzo,
Fabrizio
Chiodo,
Marco Marradi,
and
Soledad Penadés
1.
Introduction
22
2.
Design, Preparation, and Characterization of monno-GNPs
23
3.
Evaluation of monno-GNPs as Inhibitors of Carbohydrate-Mediated
gpl20 Interactions
28
4.
Validation of monno-GNPs as Inhibitors of
HIV-1/Cell
Infection
33
Acknowledgments
37
References
37
vi
Contents
3.
Nanoparticle-Mediated
Targeted Delivery of Antiretrovirals
to the Brain
41
Supriya D. Mahajan, Wing-Cheung Law, Ravikumar Aalinkeel,
Jessica Reynolds, Bindukumar B. Nair,
Ken
-Туе
Yong, Indrajit Roy,
Paras
N.
Prasad,
and Stanley A. Schwartz
1.
Introduction
42
2.
Preparation and Characterization of QD
45
3.
Physical Characterization of QDs
47
4.
Preparation of QD-Amprenavir-Tf Nanoplex
48
5.
Assessment of Amprenavir Levels Using HPLC
49
6.
Evaluating the Efficacy of Antiretroviral Containing Nanoplex Using
an In Vitro BBB Model
49
7.
Evaluation of the Antiviral Efficacy of the QD-Tf-Amprenavir
Nanobioconjugate
54
8.
Concluding Remarks
57
Acknowledgments
58
References
58
4.
Antibacterial Activity of Doxycycline-Loaded Nanoparticles
61
Ranjita Misra and Sanjeeb K. Sahoo
1.
Introduction
62
2.
Polymeric Nanoparticles
65
3.
Chitosan Nanoparticles
65
4.
Polyalkylcyanoacrylate Nanoparticles
67
5.
poly(d,l-lactide-co-glycolide)
Nanoparticles
68
6.
polyfe-caprolactone) Nanoparticles
70
7.
Doxycycline-Loaded PLGA:PCL Nanoparticles
70
8.
Conclusion
81
References
81
5.
Antimicrobial Properties of Electrically Formed Elastomeric
Polyurethane-Copper Oxide Nanocomposites for Medical
and Dental Applications
87
Z. Ahmad, M. A.
Vargas-Reus,
R.
Bakhshi,
F.
Ryan,
G. G.
Ren, F. Oktar,
and R. P.
Allaker
1.
Introduction
88
2.
Materials and Methods
90
3.
Results and Discussion
91
4.
Concluding Remarks and Future Work
97
Acknowledgments
98
References
98
Contents_________________________________________________________
vu
6.
Gastrointestinal Delivery of Anti-inflammatory Nanoparticles
101
Hamed Laroui, Shanthi V. Sitaraman, and
Didier Merlin
1.
Introduction
102
2.
Material According to Drug Application
103
3.
Anti-inflammatory Compounds as Encapsulated Drug
104
4.
NSAIDs-Loaded NPs
110
5.
Biomaterial
Choice 111
6.
Targeting NPs to the Colon: Hydrogel-Encapsulated NPs
112
7.
Conclusion
118
Acknowledgments
121
References
121
7.
Chitosan-Based Nanoparticles as a Hepatitis
В
Antigen
Delivery System
127
Filipa
Lebre, Dulce Bento, Sandra Jesus,
and Olga
Borges
1.
Introduction
128
2.
Chitosan-Based
Particle Preparation
129
3.
Physicochemical Characterization of the Particles
132
4.
Antigen Adsorption Studies
134
5.
In vitro Release Studies
135
6.
Evaluation of the Bioactivity of the Antigen
137
7.
Cell Viability Studies with Spleen Cells
137
8.
Studies on Uptake into Peyer s Patches
139
9.
Concluding Remarks
140
References
140
8.
Targeting Nanoparticles to Dendritic Cells for Immunotherapy
143
Luis J. Cruz, Paul
).
Tacken,
Felix
Rueda, Joan
Carles Domingo,
Fernando Albericio, and Carl G. Figdor
1.
Introduction
144
2.
Passive Targeting
144
3.
Active Targeting
146
4.
Paniculate Vaccines
147
5.
Targeting Gold NP Vaccines to DCs
148
6.
Experimental Procedure for Targeted AuNP Preparation
150
7.
Targeting Liposome-Based Vaccines to DCs
151
8.
Targeting Poly(Lactic-co-Glycolic Acid)-Based Vaccines to DCs
154
9.
Experimental Procedure for the Preparation of Targeted PLGA NP
155
10.
Conclusion
157
References
158
viii Contents
9.
Protein-Carbon Nanotube Sensors: Single Platform
Integrated Micro Clinical Lab for Monitoring Blood
Analytes
165
Sowmya Viswanathan, Pingzuo Li, Wonbong Choi,
Sławomir Filipek,
T. A. Balasubramaniam, and V. Renugopalakrishnan
1.
Introduction
166
2.
Prototype
167
3.
Concept
168
4.
Biosensors
169
5.
Microfluidics
169
6.
Amperometric Sensor for the Detection of Blood Analytes
169
7.
Protein Probes for Detection and Monitoring Molecular
Components of Serum
171
8.
Protein Engineering and Molecular Biology of
Probe Proteins
180
9.
Control of the Fermentation Process
181
10.
Gene Structure and Purification of Overexpressed Protein
181
11.
Immobilization of Proteins on SWCNT
183
12.
Immobilization of Proteins on Self-Assembled Monolayers
185
13.
Characterization of SWCNT Enzyme Adduct
186
14.
Mediators
186
15.
Surface Characterization
187
16.
Fabrication
188
17.
Signal Detection
188
18.
Experimental Protocol
188
19.
Conclusion
190
Acknowledgments
191
References
191
10.
Investigating the Toxic Effects of Iron Oxide Nanoparticles
195
Stefaan J. Soenen, Marcel
De
Cuyper, Stefaan
С
De Smedt,
and Kevin Braeckmans
1.
Introduction
196
2.
Materials
197
3.
Methods
199
4.
Concluding Remarks
221
Acknowledgments
221
References
222
Contents
¡χ
11.
Cytotoxidty of Gold Nanoparticles
225
Yu Pan, Matthias
Bartneck,
and
Willi Jahnen-Dechent
1.
Introduction
225
2.
Dosage and Quantification of Gold Nanoparticles
227
3.
Aggregation State of Nanoparticles in Fluids
228
4.
Cell-Based Nanotoxicity Studies
230
References
239
12.
Design of Target-Seeking Antifibrotic Compounds
243
Tero
A. H. Järvinen
1.
Introduction
244
2.
In Vivo Phage Display
246
3.
Homing Peptides
251
4.
Multifunctional Fusion Proteins
254
5.
Function of Multifunctional Fusion Protein
257
6.
Concluding Remarks
259
Acknowledgments
259
References
260
13.
Design and Fabrication of/V-Alkyl-Polyethylenimine-Stabilized
Iron Oxide Nanoclusters for Gene Delivery
263
Gang Liu, Zhiyong Wang, Seulki Lee,
Hua Ai,
and Xiaoyuan Chen
1.
Introduction
264
2.
Materials
265
3.
Methods
266
4.
Notes
269
5.
Anticipated Results
271
6.
Summary
274
Acknowledgments
274
References
275
14.
Cell-Penetrating Peptide-Based Systems for Nucleic Acid
Delivery: A Biological and Biophysical Approach
277
Sara Trabulo, Ana L. Cardoso, Ana M. S. Cardoso, Nejat
Düzgünes,
Amalia
S.
Jurado, and
Maria C.
Pedroso de Lima
1.
Introduction
278
2.
Methods for Preparation of CPP-Based Nucleic Acid Complexes
279
3.
Methods for Physical Characterization of CPP-Based Nucleic Acid
Complexes and Their Interactions with Membranes
283
4.
Methods for Evaluation of Biological Activity of CPP-Based Nucleic
Acid Complexes
292
x
Contents
5.
Methods for Evaluation of Cytotoxicity of CPP-Based Nucleic Acid
Complexes
294
6.
Concluding Remarks
296
Acknowledgments
297
References
297
15.
Multifunctional Envelope-Type
Nano
Device (MEND) for
Organelle
Targeting Via a Stepwise Membrane Fusion Process
301
Yuma Yamada, Hidetaka Akita, and Hideyoshi Harashima
1.
Programmed Packaging Concept and Construction of R8-MEND
302
2.
Screening of
Lipid
Compositions for Their Ability to Fuse with
Nuclear and Mitochondria! Membranes
304
3.
Construction of Tetra-Lamellar MEND
ÍJ-MEND)
309
4.
Nuclear Gene Delivery
314
5.
Mitochondrial Bioactive Molecule Delivery Using a Dual
Function-MITO-Porter as a MEND for Mitochondrial Delivery
318
6.
Conclusions
322
Acknowledgments
322
References
322
16.
Lipopolyplexes as Nanomedicines for Therapeutic Gene Delivery
327
Leire
García,
Koldo Urbiola,
Nejat Düzgünes,
and
Conchita Tros de llarduya
1.
Introduction
328
2.
Principle of the Method
329
3.
Experimental Procedures
329
4.
Application of Lipopolyplexes
332
5.
Concluding Remarks
336
Acknowledgments
336
References
337
17.
Interfering Nanopartides for Silencing MicroRNAs
339
Huricha Baigude and Tariq M.
Rana
1.
Introduction
340
2.
Delivery of Short Therapeutic RNAs
341
3.
Protocols
344
4.
Concluding Remarks
350
Acknowledgments
350
References
350
Contents xi
18.
Genetic Nanomedicine: Gene Delivery by Targeted Lipoplexes
355
Nejat
Diizgiineş
and
Conchita Tros de llarduya
1.
Introduction
356
2.
Preparation of Protein-Cationic Lipid-DNA Ternary Complexes
357
3.
Gene Delivery In Vitro
359
4.
Cell Viability Following Transfection
361
5.
Enhancement of Transfection In Vitro
362
6.
Targeted Lipoplexes In Vivo
364
7.
Concluding Remarks
365
Acknowledgments
365
References
366
Author Index
369
Subject Index
399
|
| any_adam_object | 1 |
| author_GND | (DE-588)129612227 |
| building | Verbundindex |
| bvnumber | BV040281235 |
| classification_rvk | WC 4355 |
| ctrlnum | (OCoLC)801378060 (DE-599)BVBBV040281235 |
| discipline | Biologie |
| edition | 1. ed. |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01617nam a2200385 cb4500</leader><controlfield tag="001">BV040281235</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20120809 </controlfield><controlfield tag="007">t|</controlfield><controlfield tag="008">120628s2012 xx ad|| |||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9780123918581</subfield><subfield code="c">hbk</subfield><subfield code="9">978-0-12-391858-1</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)801378060</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV040281235</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield><subfield code="a">DE-12</subfield><subfield code="a">DE-19</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WC 4355</subfield><subfield code="0">(DE-625)148096:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Nanomedicine</subfield><subfield code="b">infectious diseases, immunotherapy, diagnostics, antifibrotics, toxicology and gene medicine</subfield><subfield code="c">ed. by Nejat Düzgüneş</subfield></datafield><datafield tag="250" ind1=" " ind2=" "><subfield code="a">1. ed.</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Amsterdam [u.a.]</subfield><subfield code="b">Elsevier, Acad. Press</subfield><subfield code="c">2012</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">LIV, 408 S., [6] Bl.</subfield><subfield code="b">Ill., graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="1" ind2=" "><subfield code="a">Methods in enzymology</subfield><subfield code="v">509</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Medizin</subfield><subfield code="0">(DE-588)4038243-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Nanotechnologie</subfield><subfield code="0">(DE-588)4327470-5</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="0">(DE-588)4143413-4</subfield><subfield code="a">Aufsatzsammlung</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Nanotechnologie</subfield><subfield code="0">(DE-588)4327470-5</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Medizin</subfield><subfield code="0">(DE-588)4038243-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="C">b</subfield><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Düzgüneş, Nejat</subfield><subfield code="e">Sonstige</subfield><subfield code="0">(DE-588)129612227</subfield><subfield code="4">oth</subfield></datafield><datafield tag="830" ind1=" " ind2="0"><subfield code="a">Methods in enzymology</subfield><subfield code="v">509</subfield><subfield code="w">(DE-604)BV000000938</subfield><subfield code="9">509</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">Digitalisierung UB Regensburg</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025136589&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="943" ind1="1" ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-025136589</subfield></datafield></record></collection> |
| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV040281235 |
| illustrated | Illustrated |
| indexdate | 2024-12-24T02:45:07Z |
| institution | BVB |
| isbn | 9780123918581 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-025136589 |
| oclc_num | 801378060 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-12 DE-19 DE-BY-UBM |
| owner_facet | DE-355 DE-BY-UBR DE-12 DE-19 DE-BY-UBM |
| physical | LIV, 408 S., [6] Bl. Ill., graph. Darst. |
| publishDate | 2012 |
| publishDateSearch | 2012 |
| publishDateSort | 2012 |
| publisher | Elsevier, Acad. Press |
| record_format | marc |
| series | Methods in enzymology |
| series2 | Methods in enzymology |
| spellingShingle | Nanomedicine infectious diseases, immunotherapy, diagnostics, antifibrotics, toxicology and gene medicine Methods in enzymology Medizin (DE-588)4038243-6 gnd Nanotechnologie (DE-588)4327470-5 gnd |
| subject_GND | (DE-588)4038243-6 (DE-588)4327470-5 (DE-588)4143413-4 |
| title | Nanomedicine infectious diseases, immunotherapy, diagnostics, antifibrotics, toxicology and gene medicine |
| title_auth | Nanomedicine infectious diseases, immunotherapy, diagnostics, antifibrotics, toxicology and gene medicine |
| title_exact_search | Nanomedicine infectious diseases, immunotherapy, diagnostics, antifibrotics, toxicology and gene medicine |
| title_full | Nanomedicine infectious diseases, immunotherapy, diagnostics, antifibrotics, toxicology and gene medicine ed. by Nejat Düzgüneş |
| title_fullStr | Nanomedicine infectious diseases, immunotherapy, diagnostics, antifibrotics, toxicology and gene medicine ed. by Nejat Düzgüneş |
| title_full_unstemmed | Nanomedicine infectious diseases, immunotherapy, diagnostics, antifibrotics, toxicology and gene medicine ed. by Nejat Düzgüneş |
| title_short | Nanomedicine |
| title_sort | nanomedicine infectious diseases immunotherapy diagnostics antifibrotics toxicology and gene medicine |
| title_sub | infectious diseases, immunotherapy, diagnostics, antifibrotics, toxicology and gene medicine |
| topic | Medizin (DE-588)4038243-6 gnd Nanotechnologie (DE-588)4327470-5 gnd |
| topic_facet | Medizin Nanotechnologie Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025136589&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000000938 |
| work_keys_str_mv | AT duzgunesnejat nanomedicineinfectiousdiseasesimmunotherapydiagnosticsantifibroticstoxicologyandgenemedicine |