Pain research methods and protocols

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Sprache:English
Veröffentlicht: New York, NY [u.a.] Humana Press, Springer 2012
Ausgabe:2. ed
Schriftenreihe:Methods in molecular biology 851
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adam_text Contents Preface .......................................................... v Contributors. ..................................................... ix 1 Advancements in Pain Research .................................... 1 Z. David Luo 2 Genomic Methods for Clinical and Translational Pain Research ............ 9 Dan Wang, Hyungsuk Kim, Xiao-Min Wang, and Raymond Dionne 3 Two-Dimensional Gel Electrophoresis: Discovering Neuropathic Pain-Associated Synaptic Biomarkers in Spinal Cord Dorsal Horn .......... 47 Om V. Singh and Tuan-Xiang Tao 4 Whole-Cell Patch-Clamp Recordings on Spinal Cord Slices ............... 65 Ping Deng and Zao С. Хи 5 Whole-Cell Recording in Isolated Primary Sensory Neurons .............. 73 Michaels. Gold 6 Indwelling Supradural Catheters for Induction of Facial Allodynia: Surgical Procedures, Application of Inflammatory Stimuli, and Behavioral Testing .......................................... 99 Julie Wieseler, David Sprunger, Amanda Ellis, Steven F. Maier, and Linda R. Watkins 7 An Experimental Model of Headache-Related Pain ..................... 109 Rebecca M. Edelmayer, Michael H. Ossipov, and Frank Porreca 8 A Rodent Model of Trigeminal Neuralgia ............................ 121 David С Yeomans and Mikhail Klukinov 9 New Models of Experimental Parotitis and Parotid Gland Distension in Rats .............................................. 133 Akiko Okada-Ogawa, Masamichi Shinoda, Kuniya Honda, and Koichi Iwata 10 A Rat Pain Model of Facial Cancer ................................. 149 Kentaro Ono, Nozomu Harano, Kiyotoshi Inenaga, and Osamu Nakanishi 11 Orofacial Pain Models and Behavior Assessment ....................... 159 Timothy K.T. Kaan, Peter T. Ohara, and Luc Jasmin 12 Unilateral T13 and LI Dorsal Root Avulsion: Methods for a Novel Model of Central Neuropathic Pain ................................. 171 Julie Wieseler, Amanda Ellis, Steven F. Maier, Linda R. Watkins, and Scott Falci VII viii Contents 13 A Lumbosacral Ventral Root Avulsion Injury and Repair Model for Studies of Neuropathic Pain in Rats .............................. 185 Leif A. Havton 14 A Rat Chronic Pain Model of Spinal Cord Contusion Injury .............. 195 Kelli Sharp, Amin Boroujerdi, Oswald Steward, and Z. David Luo 15 The Spared Nerve Injury Model of Neuropathic Pain ................... 205 Marie Pertin, Romain-Daniel Gosselin, and Isabelle Decosterd 16 A New Rat Pain Model of Thrombus-Induced Ischemia ................. 213 Jang-Hern Lee 17 Rat Models of Pancreatitis Pain .................................... 223 Karin N. Westlund and Louis Vera-Portocarrero 18 The Monosodium Iodoacetate Model of Osteoarthritis Pain in the Rat ................................................ 239 Cheryl L. Marker and James D. Pomonis 19 K/BxN Serum Transfer Arthritis as a Model of Inflammatory Joint Pain .................................................... 249 Christina A. Christianson, Maritat Corr, Tony L. Yaksh, and Camilla I. Svensson 20 A New Rat Model of Bone Cancer Pain ............................. 261 Ruixin Zhang and Lixing Lao 21 Exposure of the Dorsal Root Ganglion to Pulsed Radiofrequency Current in a Neuropathic Pain Model of Peripheral Nerve Injury .......... 275 Danielle Perret, Doo-Sik Kim, Kang-Wu Li, and Z. David Luo Index ........................................................... 285 Μη lá. Walker, Series Eater L Bawd uta íáitst Pain Research Methods and Protocols Second Editim The advancements of medical technology, improvements in. medical care, and increased patients life span make pain research and related drug development high priorities for both the research community and pharmaceutical companies. Rapid development of basic science research touts» such as techniques of fiurometric labeling, genomic and proteomic high throughput screening, and genetically modified animals, promotes the swift acceleration of pain research to a stage al¬ lowing integrated investigations of pain processing mechanisms at the single сей and/or molecule level, and in a spatially and temporally controEed manner. Using multidisciplinary approaches» we can dissect the complicity of the sensory circuits connecting peripheral stimulation to maiadap- tive changes in the sensory pathways as well as pain perceptions at the central nervous system. Pain Research: Methods and Protocols, Second Edition provides advanced techniques and aitìmal models that are critical for integrated pain research. Written in the highly successful Methods m Molecular Bieiogf series format, chapters contain introductions to their respective topica, lists of the necessary materials and reagents, step-by -step, readily reproducible laboratory protocols må noies απ troablesbootiflg шва sveååktg known fátfalk. . . . ■ .,·.-.; ae to »owce pain researchers who may not awe ectenswe esperie»» їв 1 experienced pain researchers who would Mke to expand their research in new dirarfíatts «ti/er to new mechanisms in diferent models. . · j, ;
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Springer protocols
spellingShingle Pain research methods and protocols
Methods in molecular biology
Schmerzforschung (DE-588)4179794-2 gnd
subject_GND (DE-588)4179794-2
title Pain research methods and protocols
title_auth Pain research methods and protocols
title_exact_search Pain research methods and protocols
title_full Pain research methods and protocols ed. by Z. David Luo
title_fullStr Pain research methods and protocols ed. by Z. David Luo
title_full_unstemmed Pain research methods and protocols ed. by Z. David Luo
title_short Pain research
title_sort pain research methods and protocols
title_sub methods and protocols
topic Schmerzforschung (DE-588)4179794-2 gnd
topic_facet Schmerzforschung
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