Human virology

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Hauptverfasser: Collier, Leslie H. (VerfasserIn), Kellam, Paul 1965- (VerfasserIn), Oxford, John S. (VerfasserIn)
Format: Buch
Sprache:English
Veröffentlicht: Oxford [u.a.] Oxford Univ. Press 2011
Ausgabe:4. ed.
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Datensatz im Suchindex

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adam_text Titel: Human virology Autor: Collier, Leslie H. Jahr: 2011 Abbreviations Xltf Parti General principles 1 1 Virology: how it all began 3 l Introduction 4 2 How viruses were discovered 4 3 How they were grown in the laboratory 4 4 Sizes and shapes 5 5 Replication 6 6 The control of viral diseases 6 7 Conclusions 6 2 General properties of viruses 7 l Introduction 8 2 The architecture of viruses 8 3 Classification of viruses 14 4 The nomenclature of viruses 14 5 The range of diseases caused by viruses 15 6 Reminders 16 3 Viral replication and genetics 17 l Introduction 18 2 The molecular biology of the mammalian cell 18 3 Virus infection and replication in a host cell 19 4 Virus assembly, release from the host cell, and maturation 25 5 Genetic variation of viruses 25 6 Reminders 26 4 How viruses cause disease 27 1 Introduction 28 2 Viral factors: pathogenicity and virulence 28 3 Interactions between viruses and host cells 29 4 The spread of viruses in the host 30 5 Patterns of disease 35 6 Shedding of virus from the host 37 7 How infectious is a virus? 37 8 Reminders 37 5 Resistance of the human body to virus infections 38 l Introduction: innate and adaptive immunity 39 2 General factors in resistance 39 3 Local non-specific defences: innate immunity 40 4 The adaptive immune system 43 5 T cells and cell-mediated immunity 43 6 Harmful immune responses 47 7 Virus counter-measures to inhibit immune responses 48 8 Resistance and recovery 48 9 Reminders 49 6 Viruses and cancer in humans 50 1 Historical note 51 2 General features of viral oncogenesis 53 3 Viral oncogenes 54 4 Cellular oncogenes 54 5 Indirect mechanisms 55 6 Viruses implicated in cancers of humans 56 7 Reminders 57 7 Viruses and the community 58 1 Introduction 60 2 Definitions 60 3 What use is epidemiology? 61 4 Epidemiological methods 61 5 Serological epidemiology 62 6 Factors in the spread of viral infections 63 7 Herd immunity 64 8 Hospital-acquired infections (HAIs) 66 9 The periodicity of epidemics 67 10 Control measures 68 li Reminders 69 Part 2 Special infections 71 8 Upper respiratory tract and eye infections due to adenoviruses, coronaviruses (including SARS CoV), and rhinoviruses 73 1 Introduction 76 2 Adenoviruses 76 3 Coronaviruses 79 4 Severe acute respiratory syndrome (SARS CoV) 5 Rhinoviruses 6 Reminders 81 83 84 9 Infections caused by the paramyxoviruses: measles, RSV, mumps, parainfluenza, metapneumovirus, and the henipaviruses 85 1 Introduction 86 2 Properties of the Paramyxoviridae 86 3 Clinical and pathological aspects of paramyxovirus infections 88 4 Reminders 97 10 Orthomyxoviruses and influenza 98 1 Introduction 101 2 Properties of the orthomyxoviruses 102 3 Clinical and pathological aspects 106 4 Prevention and cure 107 5 Reminders 108 11 Gastroenteritis viruses 110 1 Introduction 114 2 Rotaviruses 114 3 Adenoviruses 117 4 Caliciviruses such as norovirus 117 5 Astroviruses 118 6 Laboratory diagnosis 119 7 Reminders 119 12 Rubella: postnatal infections 121 1 Introduction 123 2 Properties of the virus 123 3 Clinical and pathological aspects 124 4 Reminders 126 13 Parvoviruses 127 1 Introduction 129 2 Properties of the viruses 129 3 Clinical and pathological aspects 130 4 Reminders 131 14 Poxviruses 133 1 Introduction 135 2 Properties of the viruses 136 3 Clinical and pathological aspects of smallpox 137 4 Other poxvirus infections 140 5 Reminders 142 15 Papilloma- and polyomaviruses 143 1 Introduction 146 2 Properties of the viruses 146 3 Clinical and pathological aspects of papillomavirus infections 147 4 Clinical and pathological aspects of Polyomavirus infections 151 5 Reminders 152 16 Poliomyelitis and other Picornavirus infections 153 1 Properties of the viruses 155 2 Clinical and pathological aspects 157 3 Control measures 163 4 Reminders 163 17 The herpesviruses: general properties 165 1 Classification 167 2 Morphology 167 3 Genome 167 4 Replication 168 5 Reminders 169 18 The alphaherpesviruses: herpes simplex and varicella-zoster 170 1 Herpes simplex viruses 171 2 Varicella-zoster virus 175 3 Herpesvirus B 179 4 Reminders 180 19 The betaherpesviruses: cytomegalovirus and human herpesviruses 6 and 7 181 1 Cytomegalovirus 182 2 Human herpesviruses types 6 and 7 184 3 Reminders 185 20 The gammaherpesviruses: Epstein-Barr virus and Kaposi s sarcoma-associated herpesvirus 187 1 Epstein-Barr virus 189 2 Kaposi s sarcoma-associated herpesvirus (human herpesvirus 8) 192 3 Reminders 194 21 Introduction to the hepatitis viruses 195 1 Hepatitis A 196 2 Hepatitis B and deltavirus 196 3 Hepatitis C 197 4 Other hepatitis viruses 197 22 The blood-borne hepatitis viruses B and D 198 1 Properties of hepatitis B virus 200 2 Clinical and pathological aspects of hepatitis B virus infections 202 3 Properties of hepatitis D 208 4 Clinical and pathological aspects of hepatitis delta virus infections 208 5 Reminders 209 23 The blood-borne hepatitis C 210 1 Properties of hepatitis C virus 214 2 Clinical and pathological aspects of hepatitis C virus infections 215 3 The GBV viruses 216 4 Reminders 217 24 The enteric hepatitis viruses A and E 218 1 Properties of hepatitis A virus 220 2 Clinical and pathological aspects of hepatitis A virus infections 220 3 Properties of hepatitis E virus 221 4 Clinical and pathological aspects of hepatitis E virus infections 222 5 Reminders 222 25 Retroviruses and HIV 223 l Introduction 226 2 Properties of HIV 227 3 Clinical and pathological aspects of HIV 230 4 The discovery of the other human retroviruses: HIV-2, HTLV-I, and HTLV-II, III, and IV 234 5 Reminders 236 26 Lyssavirus and rabies 237 l Introduction 239 2 Properties of the virus 239 3 Clinical and pathological aspects 240 4 Reminders 244 27 Arthropod-borne viruses 245 l Introduction 249 2 Properties of the viruses 249 3 Clinical and pathological aspects of arbovirus infections 253 4 Reminders 258 28 Exotic and dangerous infections: filoviruses and arenaviruses 260 l Introduction 261 2 Filoviruses 262 3 Arenaviruses 265 4 Risk categories 267 5 Reminders 268 29 Prions and the spongiform encephalopathies 270 l Prion diseases 271 2 What are prions? 273 3 Pathogenesis and pathology 274 4 Laboratory diagnosis 274 5 Safety measures 274 6 The great bovine spongiform encephalopathy outbreak 275 7 Reminders 276 Part 3 Special syndromes 279 30 Viral diseases of the central nervous system 281 l Acute infections (Group 1) 282 2 Acute post-exposure syndromes (Group 2) 284 3 Chronic infections (Group 3) 285 4 Laboratory diagnosis 286 5 Reminders 286 31 Intrauterine and perinatal infections 287 l Pathogenesis 288 2 Foetal immunity 288 3 Specific infections 289 4 Reminders 295 32 Viral infections in patients with defective immunity l Introduction 297 298 2 Primary immunodeficiencies 3 Acquired immunodeficiencies secondary to other diseases and their treatment 298 299 4 Some special problems 5 Diagnosis and treatment 6 Reminders 300 302 303 33 Respiratory infections l The viruses 304 306 2 Seasonality 306 34 Sexually-transmitted viral infections 307 35 Resurgent and emergent viral infections l Introduction 310 311 2 Factors favouring the resurgence of old enemies 311 3 The emergence of new enemies 4 Reminders 312 314 Part 4 Practical aspects 36 37 38 315 The laboratory diagnosis of viral infections 317 l Introduction 318 2 Collecting and sending clinical specimens to the laboratory 318 3 Rapid diagnostic methods 319 4 Virus isolation in cell cultures 322 5 Detection of antiviral antibodies 324 6 Reminders 326 Control of viral diseases by immunization 327 l The technology and practicalities of virus vaccine production and development 330 2 Virus vaccines and public health 333 3 Passive immunization 334 4 New approaches to vaccine development 335 5 Reminders 336 Antiviral chemotherapy 337 l Introduction 339 2 Points of action of antivirals in the virus life cycle 340 3 The use of antivirals: general considerations 341 4 Herpes infections 342 5 Influenza 343 6 HIV infections 344 7 Interferons 345 8 The future 346 9 Reminders 346 Appendices , 349 A Safety precautions: codes of practice, disinfection, and sterilization 351 1 Introduction 352 2 The clinical phase 352 3 The laboratory phase 353 4 Further reading 353 3 Virai infections notifiable in the UK 354 C Suggestions for further reading -- 356 Index 359
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author Collier, Leslie H.
Kellam, Paul 1965-
Oxford, John S.
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Kellam, Paul 1965-
Oxford, John S.
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publishDate 2011
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publisher Oxford Univ. Press
record_format marc
spellingShingle Collier, Leslie H.
Kellam, Paul 1965-
Oxford, John S.
Human virology
Medical virology
Virus diseases
Virology methods
Virus Diseases microbiology
Virus Replication
Viruses pathogenicity
Virologie (DE-588)4063597-1 gnd
subject_GND (DE-588)4063597-1
(DE-588)4151278-9
title Human virology
title_auth Human virology
title_exact_search Human virology
title_full Human virology Leslie Collier ; Paul Kellam ; John Oxford
title_fullStr Human virology Leslie Collier ; Paul Kellam ; John Oxford
title_full_unstemmed Human virology Leslie Collier ; Paul Kellam ; John Oxford
title_short Human virology
title_sort human virology
topic Medical virology
Virus diseases
Virology methods
Virus Diseases microbiology
Virus Replication
Viruses pathogenicity
Virologie (DE-588)4063597-1 gnd
topic_facet Medical virology
Virus diseases
Virology methods
Virus Diseases microbiology
Virus Replication
Viruses pathogenicity
Virologie
Einführung
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