TNF pathophysiology molecular and cellular mechanisms ; 5 tables
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Basel [u.a.]
Karger
2010
|
| Schriftenreihe: | Current directions in autoimmunity
11 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
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MARC
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Datensatz im Suchindex
| _version_ | 1819783581347610624 |
|---|---|
| adam_text | Contents
vu
Preface
Kollias,
G.
(Vari);
Sfikakis, P.P. (Athens)
ι
Cellular Mechanisms of TNF Function in Models of Inflammation and
Autoimmunity
Apostolaki,
M.; Armaka, M.;
Victoratos, P.; Kollias, G.
(Vari)
27
Transcriptional Control of the TNF Gene
Falvo, J.V.iTsytsykova,
AV.;
Goldfeld, A.E.
(Boston,
Mass.)
61
Posttranscriptional Regulation of TNF mRNA: A Paradigm of Signal-Dependent
mRNA Utilization and Its Relevance to Pathology
Stamou, P.; Kontoyiannis,
DI. (Vari)
so Role of TNF in Pathologies Induced by Nuclear Factor
kB
Deficiency
Vlantis, K.; Pasparakis, M. (Cologne)
94
Type
I Interferon:
A New Player in TNF Signaling
Yarilina,
Α.;
Ivashkiv, L.B. (New York, N.Y.)
ios
Τ
Cells as Sources and Targets of TNF: Implications for Immunity and
Autoimmunity
Chatzidakis, I.;
Mamalaki,
С
(Heraklion)
119
TNF
-α:
An Activator of CD4+FOXP3+TNFR2+ Regulatory
Τ
Cells
Chen, X.;
Oppenheim, J.J.
(Frederick, Md.)
135
TNF and Bone
David, J.-P.; Schett, G.
(Erlangen)
145
TNF
-α
and Obesity
Tza
navarí,
T.;
Giannogonas, P.; Karalis,
K.P.
(Athens)
157
TNF in Host Resistance to Tuberculosis Infection
Quesniaux, V.FJ. (Orleans); Jacobs,
M.; Allie,
N.
(Cape Town); Grivennikov, S.
(Orleans/Moscow); Nedospasov,
S.A.
(Moscow/Berlin); Garcia, I.;
Olleros,
Ml. (Geneva);
Shebzukhov, Y. (Berlin); Kuprash, D. (Moscow); Vasseur, V.; Rose, S.; Court,
№;
Vacher,
R,;
Ryffe!,
В.
(Orleans)
180
The First Decade of Biologic TNF Antagonists in Clinical Practice: Lessons
Learned, Unresolved Issues and Future Directions
Sfikakis, P.P. (Athens)
211
Author Index
212
Subject Index
Contents
її
TNF Pathophysiology
Molecular and Cellular Mechanisms
Editors: G. Kollias,
Vari;
P.P. Sfikakis, Athens
VIII + 216
p.,
15
fig.,
2
in color,
5
tab., hard cover,
2010.
TNF is a multifunctional proinflammatory cytokine central to the development and
homeostasis of the immune system and a regulator of cell activation, differentiation
and death. Recent decades have seen an enormous scientific and clinical interest in
the function of TNF in physiology and disease. A vast amount of data has been accu¬
mulated at the biochemical, molecular and cellular level, establishing TNF as a proto¬
type for in-depth understanding of the physiological and pathogenic functions of
cytokines.
This volume covers several current aspects of TNF regulation and function, including
transcriptional and posttranscriptional control mechanisms, cellular modes of action,
signaling networks that mediate its effect, involvement in pathogenesis and clinical
outcomes of TNF antagonists. It combines basic science at the molecular and cellular
level with research in animal models of disease and clinical findings to provide a com¬
prehensive review of recent developments in TNF biology. A thorough understanding
of the mechanisms by which this key molecular player is produced and functions to
regulate cell biology, immunity and disease postulates novel paradigms on how genes
contribute to the development and physiology of biological systems. This book is
mandatory reading for molecular and cell biologists, immunologists and clinicians
interested in TNF function.
|
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| dewey-full | 616.079 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.079 |
| dewey-search | 616.079 |
| dewey-sort | 3616.079 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Book |
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| id | DE-604.BV036071968 |
| illustrated | Illustrated |
| indexdate | 2024-12-23T22:58:47Z |
| institution | BVB |
| isbn | 9783805593830 380559383X 9783805593847 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-018963234 |
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| physical | VII, 215 S. Ill., graph. Darst. |
| publishDate | 2010 |
| publishDateSearch | 2010 |
| publishDateSort | 2010 |
| publisher | Karger |
| record_format | marc |
| series | Current directions in autoimmunity |
| series2 | Current directions in autoimmunity |
| spellingShingle | TNF pathophysiology molecular and cellular mechanisms ; 5 tables Current directions in autoimmunity Pathophysiologie (DE-588)4044898-8 gnd Tumor-Nekrose-Faktor (DE-588)4202932-6 gnd |
| subject_GND | (DE-588)4044898-8 (DE-588)4202932-6 (DE-588)4143413-4 |
| title | TNF pathophysiology molecular and cellular mechanisms ; 5 tables |
| title_auth | TNF pathophysiology molecular and cellular mechanisms ; 5 tables |
| title_exact_search | TNF pathophysiology molecular and cellular mechanisms ; 5 tables |
| title_full | TNF pathophysiology molecular and cellular mechanisms ; 5 tables vol. ed.: G. Kollias ... |
| title_fullStr | TNF pathophysiology molecular and cellular mechanisms ; 5 tables vol. ed.: G. Kollias ... |
| title_full_unstemmed | TNF pathophysiology molecular and cellular mechanisms ; 5 tables vol. ed.: G. Kollias ... |
| title_short | TNF pathophysiology |
| title_sort | tnf pathophysiology molecular and cellular mechanisms 5 tables |
| title_sub | molecular and cellular mechanisms ; 5 tables |
| topic | Pathophysiologie (DE-588)4044898-8 gnd Tumor-Nekrose-Faktor (DE-588)4202932-6 gnd |
| topic_facet | Pathophysiologie Tumor-Nekrose-Faktor Aufsatzsammlung |
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