Heat shock proteins in cancer

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Sprache:English
Veröffentlicht: Dordrecht Springer 2007
Schriftenreihe:Heat shock proteins 2
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245 1 0 |a Heat shock proteins in cancer  |c ed. by Stuart K. Calderwood ... 
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Datensatz im Suchindex

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adam_text TABLE OF CONTENTS list of Contributors vii 1. The Hsp90 Chaperone Machinery Acts at Protein Folding Clefts to Regulate Both Signaling Protein Function and Protein Quality Control 1 William B. Pratt, Yoshihiro Morishima and Yoichi Osawa 2. Implications of Heat Shock Proteins in Carcinogenesis and Cancer Progression 31 Daniel R. Ciocca, Mariéi A. Fanelli, F. Dario Cuello-Carrión and Stuart К. Calderwood 3. HSR: An Emerging Factor in Cancer 53 Stuart K. Calderwood, Md Abdul Khaleque, Ajit Bharti and Daniel R. Ciocca 4. Anti-apoptotic, Tumorigenic and Metastatic Potential of Hsp27 (HspBl) and aB-Crystallin (HspB5): Emerging Targets for the Development of New Anti-Cancer Therapeutic Strategies 73 Andre-Patrick Arrigo 5. Heat Shock Protein-27 (Hsp-27) in Breast Cancers: Regulation of Expression and Function 93 Vishwanie S. Budhram-Mahadeo and Richard J. Heads 6. Role of Heat Shock Protein Hsp25/27 in the Metastatic Spread of Cancer Cells 131 María A. Bausero and Alexzander Asea 7. Heat Shock Chaperone Mortalin and Carcinogenesis 141 Custer C. Deocaris, Sunil C. Kaul and Renu Wadhwa 8. Role of Molecular Chaperones in Cell Senescence 159 Michael Y. Sherman and Julia Yaglom vi Table of contents 9. Involvement of Heat Shock Proteins in Protection of Tumor Cells from Genotoxic Stresses 169 Cornelia O Callaghan-Sunol and Vladimir L. Gabai 10. Hsp70 in Tumors: Friend or Foe? 191 Cristina Bonorino and Ana Paula Souza 11. Hsp70 and Hsp27 as Pharmacological Targets in Apoptosis Modulation for Cancer Therapy 209 M. Brunet, С. Didelot, S. Subramaniam, A.L. Rérole, A. de Thonel and C. Garrido 12. Heat Shock Protein 90: The Cancer Chaperone 231 Len Neckers 13. Targeting Hsp90 Function to Treat Cancer: Much More to be Learned 253 Luke Whitesell and Catherine A. McLellan 14. Small-Molecule HSP90 Inhibitors: Applications in Cancer and Neurodegenerative Diseases 275 Adeela Kamal, Srinivas Kasibhatla, Marco Biamonte, Hong Zhang, Lin Zhang, Karen Lundgren, Marcus F. Boehm and Francis J. Burrows 15. Drugging the Hsp90 Molecular Chaperone Machine for Cancer Treatment 295 J.L. Holmes, S. Y. Sharp and P. Workman 16. Cdc37 and Protein Kinase Folding 331 Robert Matts and Avrom J. Copian 17. The Hevated Levels of Heat Shock Proteins in Cancer: A Suitable Case for Treatment? 351 Stuart K. Calderwood, Daniel R. Ciocca, Phillip J. Gray Jnr, Nava Zaarur, Stan Lepchammer and Michael Y. Sherman 18. Hsp70-Based Anticancer Vaccines: Chaperoning the Immune Response 367 Jianlin Gong, Jimmy R. Theriault and Stuart K. Calderwood 19. Piloting of Exogenous Antigen into Cross-Presentation Pathway by Heat Shock Proteins 383 Yasuaki Tamura, Goro Kutomi, Jun Oura, Toshihiko Torigoe and Noriyuki Sato Index 397
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isbn 1402064004
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language English
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physical X, 398 S. Ill., graph. Darst.
publishDate 2007
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publishDateSort 2007
publisher Springer
record_format marc
series Heat shock proteins
series2 Heat shock proteins
spellingShingle Heat shock proteins in cancer
Heat shock proteins
Cancer Etiology
Cancer Treatment
Heat shock proteins
Heat-Shock Proteins metabolism
Heat-Shock Proteins therapeutic use
Neoplasms drug therapy
Neoplasms therapy
Krebs Medizin (DE-588)4073781-0 gnd
Hitzeschock-Proteine (DE-588)4255487-1 gnd
subject_GND (DE-588)4073781-0
(DE-588)4255487-1
title Heat shock proteins in cancer
title_auth Heat shock proteins in cancer
title_exact_search Heat shock proteins in cancer
title_full Heat shock proteins in cancer ed. by Stuart K. Calderwood ...
title_fullStr Heat shock proteins in cancer ed. by Stuart K. Calderwood ...
title_full_unstemmed Heat shock proteins in cancer ed. by Stuart K. Calderwood ...
title_short Heat shock proteins in cancer
title_sort heat shock proteins in cancer
topic Cancer Etiology
Cancer Treatment
Heat shock proteins
Heat-Shock Proteins metabolism
Heat-Shock Proteins therapeutic use
Neoplasms drug therapy
Neoplasms therapy
Krebs Medizin (DE-588)4073781-0 gnd
Hitzeschock-Proteine (DE-588)4255487-1 gnd
topic_facet Cancer Etiology
Cancer Treatment
Heat shock proteins
Heat-Shock Proteins metabolism
Heat-Shock Proteins therapeutic use
Neoplasms drug therapy
Neoplasms therapy
Krebs Medizin
Hitzeschock-Proteine
url http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017188685&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
volume_link (DE-604)BV023011348
work_keys_str_mv AT calderwoodstuartk heatshockproteinsincancer