Ion channels

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Bibliographische Detailangaben
Weitere Verfasser: Fermini, Bernard (HerausgeberIn)
Format: Buch
Sprache:English
Veröffentlicht: Berlin [u.a.] Springer 2008
Schriftenreihe:Topics in medicinal chemistry 3
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Datensatz im Suchindex

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adam_text CONTENTS RECENT ADVANCES IN ION CHANNEL SCREENING TECHNOLOGIES B. FERMINI 1 ROLE OF KV7 AND CAV3 ION CHANNELS IN PAIN D. S. KRAFTE * J. KRAJEWSKI * A. GERLACH * M. SUTO 27 POTASSIUM CHANNELS: ONCOGENIC POTENTIAL AND THERAPEUTIC TARGET FOR CANCERS Z.WANG 55 PHARMACOLOGICAL RESCUE OF MUTANT CFTR FUNCTION FOR THE TREATMENT OF CYSTIC FIBROSIS F. VAN GOOR * S. HADIDA * P. GROOTENHUIS 91 ON THE PROCESS OF FINDING NOVEL AND SELECTIVE SODIUM CHANNEL BLOCKERS FOR THE TREATMENT OF DISEASES B. T. PRIEST 121 KVL.5 POTASSIUM CHANNEL INHIBITORS FOR THE TREATMENT AND PREVENTION OF ATRIAL FIBRILLATION A.LAGRUTTA-L.KISS-J.J. SALATA 145 SUBJECT INDEX 169 GESCANNT DURCH BIBLIOGRAFISCHE INFORMATIONEN HTTP://D-NB.INFO/988058774 DIGITALISIERT DURCH REFERENCES 23 TOP MED CHEM (2008) 3: 1-25 DOI 10.1007/7355_2008_024 SPRINGER-VERLAG BERLIN HEIDELBERG PUBLISHED ONLINE: 4 JUNE 2008 RECENT ADVANCES IN ION CHANNEL SCREENING TECHNOLOGIES BERNARD FERMINI PFIZER GLOBAL RESEARCH AND DEVELOPMENT, EXPLORATORY SAFETY DIFFERENTIATION, EASTERN POINT ROAD, MAIL STOP 4083, GROTON, CT 06340, USA BERNARD.FERMINI@PFIZER.COM 1 INTRODUCTION 2 2 ION CHANNELS AS DRUG TARGETS 3 3 HISTORICAL PERSPECTIVE 6 4 METHODS FOR EVALUATING ION CHANNELS 11 4.1 RADIOLIGAND BINDING ASSAYS 11 4.2 FLUORESCENCE ASSAYS USING MEMBRANE POTENTIAL DYES 12 4.3 ION FLUX ASSAYS 14 5 AUTOMATED ELECTROPHYSIOLOGY TECHNOLOGIES 15 5.1 AUTOMATED ELECTROPHYSIOLOGY-PLANAR PATCH TECHNOLOGY 15 5.2 IONWORKS 18 5.3 THE IONWORKS QUATTRO - POPULATION PATCH CLAMPING 19 5.4 PATCHXPRESS 7000A 20 5.5 QPATCH 20 5.6 PORT-A-PATCH 21 5.7 NON-PLANAR SYSTEM 21 6 FUTURE PERSPECTIVES AND CHALLENGES 22
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publishDate 2008
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series Topics in medicinal chemistry
series2 Topics in medicinal chemistry
spellingShingle Ion channels
Topics in medicinal chemistry
Ion Channels
Ion channels
Ionenkanal (DE-588)4138699-1 gnd
Pathophysiologie (DE-588)4044898-8 gnd
subject_GND (DE-588)4138699-1
(DE-588)4044898-8
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title Ion channels
title_auth Ion channels
title_exact_search Ion channels
title_full Ion channels vol. ed.: Bernard Fermini ...
title_fullStr Ion channels vol. ed.: Bernard Fermini ...
title_full_unstemmed Ion channels vol. ed.: Bernard Fermini ...
title_short Ion channels
title_sort ion channels
topic Ion Channels
Ion channels
Ionenkanal (DE-588)4138699-1 gnd
Pathophysiologie (DE-588)4044898-8 gnd
topic_facet Ion Channels
Ion channels
Ionenkanal
Pathophysiologie
Aufsatzsammlung
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