Biomedical surfaces

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1. Verfasser: Ramsden, Jeremy (VerfasserIn)
Format: Buch
Sprache:English
Veröffentlicht: Boston [u.a.] Artech House 2008
Schriftenreihe:Engineering in medicine & biology
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MARC

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Datensatz im Suchindex

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adam_text Contents Preface xiii Introduction 1 1 The deposition, adsorption, and desorption of biomacro- molecules 23 1.1 Elementary physico-chemical considerations ........ 24 1.2 Monolayer adsorption ..................... 32 1.2.1 Effect of flow rate ................... 38 1.3 Desorption ........................... 41 1.4 Competitive adsorption and protein exchange ....... 42 1.5 Multilayer adsorption ..................... 44 1.6 Multicomponent adsorption ................. 45 1.7 Adsorption onto heterogeneous surfaces ........... 45 1.8 Conclusions .......................... 46 1.9 Further reading ........................ 47 2 Chemical and physical attributes of biomedical surfaces 49 2.1 Interaction energetics ..................... 51 2.1.1 Pairwise interactions ................. 51 2.1.2 Protein surface heterogeneity ............ 54 2.1.3 Three-body interactions ............... 57 2.2 Wettability .......................... 59 2.2.1 The wetting transition ................ 61 2.2.2 Wetting dynamics ................... 62 vii viii CONTENTS 2.2.3 Dewetting dynamics ................. 63 2.2.4 Wetting on rough and chemically inhomogeneous sur¬ faces .......................... 65 2.3 Morphology .......................... 66 2.3.1 Roughness ....................... 67 2.3.2 Porosity ........................ 70 2.4 Chemistry ........................... 71 2.4.1 The principles of molecular recognition ....... 71 2.5 Biodegradability ........................ 78 2.6 Further reading ........................ 79 3 The basis of biofluid compatibility 81 3.1 Water ............................. 82 3.2 Hemocompatibility ...................... 85 3.2.1 The composition of human blood .......... 86 3.2.2 Initial recognition events ............... 87 3.2.3 The coagulation cascade ............... 90 3.2.4 The immune system ................. 94 3.2.5 The innate immune system .............. 95 3.2.6 The adaptive immune system ............ 96 3.2.7 Hemodialysis to combat renal failure ........ 99 3.2.8 Stents ......................... 100 3.3 Hemocompatibility testing .................. 102 3.4 Urine compatibility ...................... 106 3.5 Lachrymal secretions ..................... 108 3.6 Buccal secretions ....................... 108 3.7 Bioanalytical surfaces ..................... 110 3.8 Biocompatibility testing of fluids other than blood ..... Ill 3.8.1 Quantifying biocompatibility ............. Ill 3.9 Further reading ........................ 112 4 Cell and tissue interactions with artificial surfaces 113 4.1 Principles of eukaryotic cell architecture .......... 114 4.2 Cell adhesion ......................... 117 4.3 Principles of tissue architecture ............... 122 CONTENTS ix 4.3.1 Inflamed tissue .................... 123 4.4 Bone .............................. 123 4.5 Assimilation .......................... 125 4.6 The adhesion of cells to artificial surfaces .......... 127 4.6.1 Cell spreading ..................... 129 4.6.2 Substratum topography effects on cell response . . 130 4.7 Implant cytotoxicity ..................... 132 4.8 Bacterial infection of implants ................ 133 4.8.1 Bacterial structure and dynamics .......... 134 4.8.2 Biofilms ........................ 137 4.8.3 Bacterial adhesion .................. 137 4.9 Further reading ........................ 138 5 Lubrication, wear, and corrosion 139 5.1 Fundamentals of tribology .................. 140 5.1.1 Dry friction ...................... 140 5.1.2 Lubrication ...................... 141 5.2 Friction in hip endoprostheses ................ 143 5.3 Possible physiological effects of particles released as a result of wear ............................. 146 5.3.1 Physical properties of (nano) particles ........ 148 5.3.2 Chemical properties of (nano) particles ....... 148 5.3.3 Corrosion ....................... 152 5.4 Further reading ........................ 155 В Surface generation, engineering, and coating 157 6.1 Machining ........................... 159 6.1.1 Mechanical operations ................ 161 6.1.2 Laser micromachining ................ 164 6.1.3 Electrochemical methods ............... 168 6.2 Surface engineering ...................... 168 6.2.1 Plasma modification ................. 170 6.2.2 Ion implantation ................... 170 6.2.3 Anodizing ....................... 172 6.3 Surface coating ........................ 172 x CONTENTS 6.3.1 Physical vapor deposition (PVD) .......... 174 6.3.2 Chemical vapor deposition (CVD) .......... 175 6.3.3 Ceramic coatings by plasma spraying ........ 179 6.3.4 Sol-gel coatings .................... 180 6.3.5 Soft self-assembled coatings ............. 182 6.4 Prospects ........................... 190 6.5 Further reading ........................ 190 7 The metrology of biomedical surfaces 193 7.1 Energetics ........................... 196 7.1.1 Wetting ........................ 196 7.1.2 Probe particles .................... 198 7.2 Morphology .......................... 200 7.2.1 Contact techniques .................. 200 7.2.2 Porosity ........................ 207 7.2.3 Noncontact (optical) techniques ........... 208 7.2.4 Layer thickness and density ............. 214 7.3 Dynamical structure measurements ............. 215 7.3.1 Viscoelasticity ..................... 215 7.3.2 Nonimaging uses of scanning probe microscopy . . 215 7.3.3 Tribology ....................... 217 7.4 Chemical surface analysis .................. 218 7.4.1 Electrical surface properties ............. 221 7.4.2 Protein adsorption and desorption .......... 221 7.4.3 Layer chemistry and multicomponent distribution . 225 7.5 Cytometry ........................... 226 7.6 Analysis of cell internal components ............. 233 7.6.1 Microarrays ...................... 234 7.6.2 Two-dimensional gel electrophoresis (2DGE) .... 239 7.7 Multifunctional metrology .................. 241 7.8 Further reading ........................ 242 8 Prospects for smart and nanomaterials 245 8.1 The nature of responsiveness ................. 248 8.2 Bioactive coatings ....................... 252 CONTENTS xi 8.2.1 Cell adhesion-promoting coatings .......... 254 8.2.2 Cell adhesion-inhibiting coatings .......... 255 8.2.3 Drug delivery surfaces ................ 255 8.2.4 Biocidal surfaces ................... 257 8.3 Nanomaterials ......................... 258 8.4 A complexity sciences perspective for biomaterials design . 259 8.5 Recapitulation ......................... 261 8.6 Further reading ........................ 262 List of acronyms 263 About the author 265 Index 267
any_adam_object 1
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institution BVB
isbn 9781596932401
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language English
lccn 2008297862
oai_aleph_id oai:aleph.bib-bvb.de:BVB01-016695010
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physical xviii, 270 p. ill.
publishDate 2008
publishDateSearch 2008
publishDateSort 2008
publisher Artech House
record_format marc
series2 Engineering in medicine & biology
spellingShingle Ramsden, Jeremy
Biomedical surfaces
Biomatériaux - Surfaces
Surfaces (Biologie)
Biomedical materials Surfaces
Biological interfaces
title Biomedical surfaces
title_auth Biomedical surfaces
title_exact_search Biomedical surfaces
title_full Biomedical surfaces Jeremy Ramsden
title_fullStr Biomedical surfaces Jeremy Ramsden
title_full_unstemmed Biomedical surfaces Jeremy Ramsden
title_short Biomedical surfaces
title_sort biomedical surfaces
topic Biomatériaux - Surfaces
Surfaces (Biologie)
Biomedical materials Surfaces
Biological interfaces
topic_facet Biomatériaux - Surfaces
Surfaces (Biologie)
Biomedical materials Surfaces
Biological interfaces
url http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016695010&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
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