Development of novel antimicrobial agents emerging strategies

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Veröffentlicht: Norfolk Horizon Scient. Press 2001
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adam_text Contents List of Contributors vii Preface x Section 1 - The Problem of Antimicrobial Resistance 1. Are We on the Threshold of the Post-Antibiotic Era? 1 Karl Lohner and Erich Staudegger 2. Origins and Evolution of Antibiotic and Multiple Antibiotic 17 Resistance in Bacteria Ruth M. Hall and Christina M. Collis 3. Antimicrobial Peptide Resistance Mechanisms in Bacteria 31 ArdenAspedon and Eduardo A. Groisman Section 2 - Microbial Genomics: Novel Targets and Vaccines 4. Genetic Engineering of Novel Macrolide Antibiotics 45 Robert McDaniel and Leonard Katz 5. Granulysin, A Novel Mediator of Antimicrobial Activity of Cytolytic T-cells 61 Steffen Stenger, Alan M. Krensky and Robert L. Modlin 6. The Immunostimulatory Properties of Bacterial DNA 71 David S. Pisetsky 7. Bacteria-Mediated DNA Transfer for Gene Therapy and Genetic Vaccination 81 Siegfried Weiss and Trinad Chakraborty 8. Potential Mucosal Adjuvants For Human Use 91 Mari Ohmura, Raymond J. Jackson, Yoshifumi Takeda and Jerry R. McGhee 9. Attenuated Bacteria as Delivery Vehicles for Helicobacter pylori Vaccines 107 Thomas G. Blanchard and Steven J. Czinn 10. Development of an Adhesin Vaccine to Prevent Urinary Tract Infection 123 Matthew A. Mulvey, Scott J. Hultgren and Solomon Langermann Section 3 - Innate Immunity: Antimicrobial Peptides 11. Antimicrobial Peptides in Innate Immunity 139 Tomas Ganz and Robert I. Lehrer 12. The Role of Membrane Lipid Composition in Cell Targeting 149 of Antimicrobial Peptides Karl Lohner iv 13. Molecular Mechanisms of Membrane Perturbation by Antimicrobial Peptides 167 Katsumi Matsuzaki 14. Molecular Mechanism of Cell Selectivity by Linear Amphipatic 183 a-helical and Diasteriomeric Antimicrobial Peptides Ziv Oren and Yechiel Shai 15. Molecular Interactions Involved in Bactericidal Activities of Lantibiotics 205 Ulrike Pag and Hans-Georg Sahl 16. Cyclic Cystine-knot (3-Stranded Antimicrobial Peptides: 215 Occurrence, Design and Synthesis James P. Tarn, Yi-An Lu, Jin-Long Yang and Qitao Yu 17. Synthetic Combinatorial Libraries: An Emerging Approach 241 Toward the Identification of Novel Antibiotics Sylvie E. Blondelle 18. The Commercial Development of the Antimicrobial Peptide Pexiganan 261 Michael Zasloff Appendix 271 Index 273 v
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spellingShingle Development of novel antimicrobial agents emerging strategies
Antiinfective Agents cabt
title Development of novel antimicrobial agents emerging strategies
title_auth Development of novel antimicrobial agents emerging strategies
title_exact_search Development of novel antimicrobial agents emerging strategies
title_full Development of novel antimicrobial agents emerging strategies ed. by Karl Lohner
title_fullStr Development of novel antimicrobial agents emerging strategies ed. by Karl Lohner
title_full_unstemmed Development of novel antimicrobial agents emerging strategies ed. by Karl Lohner
title_short Development of novel antimicrobial agents
title_sort development of novel antimicrobial agents emerging strategies
title_sub emerging strategies
topic Antiinfective Agents cabt
topic_facet Antiinfective Agents
url http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=022026515&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
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