Phylogenetic perspectives in immunity the insect host defense
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Austin, Tex.
Landes
1994
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| Schriftenreihe: | Molecular biology intelligence unit
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| 245 | 1 | 0 | |a Phylogenetic perspectives in immunity |b the insect host defense |c Jules A. Hoffmann ... |
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Datensatz im Suchindex
| _version_ | 1819767140013572096 |
|---|---|
| adam_text | MOLECULAR
BIOLOGY
INTELLIGENCE
UNIT
PHYLOGENETIC PERSPECTIVES
IN IMMUNITY: THE INSECT
HOST DEFENSE
Jules A Hoffmann
CNR5 and Universite Louis Pasteur
Strasbourg, France
Charles A Janeway, Jr
Yale University
New Haven, Connecticut, USA
Shunji Natori
University of Tokyo
Tokyo,Japan
R G LANDES COMPANY
AUSTIN
CONTENTS
SECTION 1: DEFENSE MOLECULES 1
1 Cecropins: Antibacterial Peptides from Insects and Pigs 3
Hans G Boman
Introduction: The Isolation and the Structure of the Cecropins 3
The Precursors of the Cecropins and Their Processing 5
Antibacterial Activity and Mechanism of Action of Cecropins 7
Gene Structures for Cecropins and Their Induction 9
Discussion 12
2 Defensins and Protegrins: Vertebrate Analogues
of Arthropod Antimicrobial Peptides 19
Robert I Lehrer, Sylvia S L Harwig, Tomas Ganz
Definitions 19
Antimicrobial Properties 20
Cytotoxic Properties 22
Structure 23
Molecular Biology 23
Interspecies Differences 25
Evolutionary Aspects 25
3 Antibacterial Molecules from Frogs, Sharks and Man 31
Michael Zasloff
Introduction 31
Magainin 31
Pharmacologic Properties of Animal Antibiotics 32
The Mechanism of Action of Magainin 32
Biology of the Magainin Peptide Family in Xenopus laevis 33
Molecular Diversity of Amphibian Antibiotic Peptides 34
MSI-78: Development as a Broad-Spectrum Topical Antibiotic Agent 34
Antibiotic Peptides as Anticancer Agents 35
Discover) Strategy 35
Scjualamine 36
Phylogenetic Exploration 37
4 Antibacterial Peptides/Polypeptides in the Insect Host Defense:
A Comparison with Vertebrate Antibacterial Peptides/Polypeptides 43
Charles Hetru, Philippe Bulet, Stephane Cociancich, Jean-Luc Dimarcq,
Danible Hoffmann, Jules A Hoffmann
Peptides Forming Amphipathic a-Helices 44
Peptides with Intra-molecular Disulfide Bridges 47
Proline-Rich Antibacterial Peptides 52
Glycine-Rich Antibacterial Polypeptides 54
Other Antibacterial Peptides/Polypeptides 57
Concluding Remarks 60
5 Defense Molecules in Host Defense and Development of Insects 67
Shunji Natori
Introduction 67
Dual Roles of Sarcophaga Lectin in Defense and Development 68
Phylogenetic Aspect of Sarcophaga Lectin 69
Dual Roles of Antibacterial Proteins 70
Discussion 73
SECTION 2: IMMUNE REACTIONS IN ARTHROPODS 77
6 Clotting Cascade in the Immune Response of Horseshoe Crab 79
Sadaaki Iwanaga, Shun-ichiro Kawabata, Yoshiki Miura, Noriaki Seki,
Takeshi Shigenaga, Tatsushi Muta
Introduction 79
Limulus Hemocytes 79
Hemolymph Coagulation System 80
Limulus Factor G and Factor G 82
Limulus Serpin Family 89
Hemocyte-Derived Granular Components 91
Summary 92
7 Pattern Recognition in Invertebrates:
The P-1,3-Glucan Binding Proteins 97
Kenneth Soderhall, Mats W Johansson, Lage Cerenius
Recognition of Fungal P-1,3-Glucans 97
Biochemical Characteristics of the Arthropod PGBPs 99
Structure of the |3GBP 99
The Membrane Receptor Protein for PGBP 101
Function 101
Comparison to Vertebrate Pattern Recognition 102
8 Midgut Antibacterial Defenses of Manduca sexta
Following Infection and During Metamorphosis 105
Peter E Dunn, Tony J Bohnert, Virginia Russell
Antibacterial Defenses of M sexta 105
Antibacterial Defenses of the M sexta Alimentary Canal 107
Summary T 110
SECTION 3: RECOGNITION SYSTEMS 113
9 The Role of Microbial Pattern Recognition in Self:
Non-Self Discrimination in Innate and Adaptive Immunity 115
Charles A Janeway, Jr
Pattern Recognition in Vertebrates and Invertebrates 116
The Evolution of the Adaptive Immune Response 117
Transitional Lymphoid Cell Types
Suggest a Phylogenetic Origin of Adaptive Immunity 119
The Interplay Between Innate and Adaptive Immunity in Vertebrates 120
10 The Role of Pattern Recognition Molecules
in Mammalian Immunity 123
Neil S Harris, R Alan Ezekowitz
Introduction 123
The Mannose-Binding Protein 123
The Macrophage Mannose Receptors
as a Pattern Recognition Molecule in First Line Host Defense 125
Conclusions 127
11 Stepwise Evolution of Major Functional Systems
in Vertebrates, Including the Immune System 133
Eric H Davidson
Evolutionary Affinities
Between Deuterostome Invertebrates and Vertebrates 133
Basic Deuterostome Immune Defense System 134
Stepwise Evolution of Vertebrate Systems 137
12 Molecular and Phylogenetic Aspects
of the Complement System 143
Alister W Dodds
The Complement System 143
Phylogeny of the Complement System 147
Evolution of the Complement System 151
Summaiy , 153
SECTION 4: CONTROL OF IMMUNE GENE EXPRESSION 157
13 Invertebrate Cytokines: Principal Mediators
of Host Defenses in Invertebrates 159
Gail S Habicht, Gregory Beck
Introduction 159
Materials and Methods 160
Results and Discussion 161
14 Immune Gene Expression in Drosophila 167
Marie Meister, Philippe Georgel, Bruno Lemaitre, Christine Kappler,
Marie Lagueux, Jean-Marc Reichhart, Jules A Hoffinann
Gene Cloning and Transcriptional Profiles 167
Control of Gene Expression 171
The Morphogen Dorsal is Activated
During the Immune Response of Drosophila 176
Perspectives 178
15 Activation of the Immune Response in Drosophila 183
Dan Hultmark
Introduction 183
Cecropins 184
The Drosophila Cecropin Gene Cluster 184
Andropin 185
Cecropin Induction In Vitro 185
Transcriptional Regulation of the Cecropin Genes 185
General Outlook 186
Index 189
|
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| building | Verbundindex |
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| id | DE-604.BV026146887 |
| illustrated | Illustrated |
| indexdate | 2024-12-24T00:38:31Z |
| institution | BVB |
| isbn | 1570590435 |
| language | Undetermined |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-021734968 |
| oclc_num | 246811228 |
| open_access_boolean | |
| owner | DE-188 |
| owner_facet | DE-188 |
| physical | 197 S. Ill., graph. Darst. |
| publishDate | 1994 |
| publishDateSearch | 1994 |
| publishDateSort | 1994 |
| publisher | Landes |
| record_format | marc |
| series2 | Molecular biology intelligence unit |
| spellingShingle | Phylogenetic perspectives in immunity the insect host defense Insekten (DE-588)4027110-9 gnd Wirbeltiere (DE-588)4066376-0 gnd Immunologie (DE-588)4026637-0 gnd Immunreaktion (DE-588)4133841-8 gnd |
| subject_GND | (DE-588)4027110-9 (DE-588)4066376-0 (DE-588)4026637-0 (DE-588)4133841-8 |
| title | Phylogenetic perspectives in immunity the insect host defense |
| title_auth | Phylogenetic perspectives in immunity the insect host defense |
| title_exact_search | Phylogenetic perspectives in immunity the insect host defense |
| title_full | Phylogenetic perspectives in immunity the insect host defense Jules A. Hoffmann ... |
| title_fullStr | Phylogenetic perspectives in immunity the insect host defense Jules A. Hoffmann ... |
| title_full_unstemmed | Phylogenetic perspectives in immunity the insect host defense Jules A. Hoffmann ... |
| title_short | Phylogenetic perspectives in immunity |
| title_sort | phylogenetic perspectives in immunity the insect host defense |
| title_sub | the insect host defense |
| topic | Insekten (DE-588)4027110-9 gnd Wirbeltiere (DE-588)4066376-0 gnd Immunologie (DE-588)4026637-0 gnd Immunreaktion (DE-588)4133841-8 gnd |
| topic_facet | Insekten Wirbeltiere Immunologie Immunreaktion |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=021734968&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT hoffmannjulesa phylogeneticperspectivesinimmunitytheinsecthostdefense |