Four centuries of clinical chemistry

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1. Verfasser: Rosenfeld, Louis (VerfasserIn)
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Sprache:English
Veröffentlicht: Amsterdam Gordon & Breach 1999
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adam_text Contents Preface xv I Introduction. Anatomy, Disease, and Therapy. Transition 1 of Alchemy to Chemistry. Paracelsus. Uroscopy. Van Helmont and Discovery of Gas. Sylvius and Iatrochemistry. Iatrophysicists (Iatromechanists). II Introduction. Robert Boyle. Color Test and Chemical 23 Reaction. Analysis of Blood. The Gaseous State and Pneumatic Chemistry. The New Chemistry of Combustion and Respiration. Nomenclature. III Introduction. Urinary Calculi and Discovery of Uric Acid. 37 Cystine and Cystinuria. Preparation and Analysis of Urea. Analysis of Urine. Chemistry vs Physiology. William Prout Discovers the Acid of Gastric Juice. Alexander Marcet, Golding Bird, and Analysis of Calculi. IV Introduction. Protein and Food Shortage. Analysis of 55 Nitrogen: Methods of Dumas and Will-Varrentrapp. Kjeldahl Analysis. Nessler s Reagent. Berzelius: International Authority. Vital Force. Wohler s Synthesis of Urea. Organic Synthesis by Berthelot. The Analytical Balance. Volumetric (Titrimetric) Analysis. Karl Mohr. V Introduction. Library Medicine, Bedside Medicine, and the 77 Stigma of Dissection. The Stethoscope and the Changing Patient-Physician Relationship. The Changing Role of Therapy. Measurement and the Focus on Specific Diseases. Bright s Disease, Albuminuria, and Scientific Medicine. Body Fluids and the Examination of Blood. Chemical Analysis: Voices Pro and Con. x CONTENTS VI Rees and the Estimation of Urea and Sugar in Blood. 99 Bence Jones Protein. A Theory of Diabetes. Alkaline Tide. Medical Education. Liebig s Concept of Stone Formation. Liebig s Laboratory at Giessen. The Impact of Animal Chemistry. Animal Chemistry Society. Chemistry in the Service of Society, Technology, and Medicine. Chemistry Separates from Medicine. Chemistry and the Apothecaries Act of 1815. Clinical Chemistry—A False Start for a New Identity. VII Textbooks on Urine and Blood Analysis (1863-1899). 131 Albuminuria and Insurance Companies. Esbach s Method for Urine Protein. Detection of Protein by Dipstick. VIII Cholera, Acidosis, and Fluid-Electrolyte Therapy in 1832. 151 Chemical Studies and Therapeutic Responses When Cholera Returns. The Early History of Polyuria, Glycosuria, and Hyperglycemia. Sugar Analysis and Alkaline Copper Sulfate. Fehling s Solution. Fermentation. Polariscope-Saccharimeter. Claude Bernard Discovers the Glycogenic Function of the Liver. Chemical Findings in Diabetic and Other Forms of Acidosis. Van Slyke s Apparatus for Measuring Bicarbonate Concentration and Detection of Acidosis. Milliequivalents and Cation-Anion Balance. Discovery of Insulin. IX Respiration and Combustion. Early Studies on Blood 185 Gases. Hoppe-Seyler Isolates Hemoglobin. Physiological Chemistry and Zeitschrift fur Physiologische Chemie. Quantitation of Red Cells and Hemoglobin. Hematocrit, Urine Sediments, and the Centrifuge. Hydrogen Electrode. S0rensen, pH, and Buffers. Henderson- Hasselbalch Equation and New Definitions for Acid and Base. Glass Electrode. Beckman pH Meter. X Early Development and Use of the Microscope. Clinical 215 Microscopy and the Evolution of Clinical Laboratories in Great Britain. Emergence of Clinical Laboratories in the United States. Medicine and the Scientific CONTENTS xi Method. The Laboratory. Clinical Laboratory Testing (1900-1920). Medical Technologists, Commercial Laboratories, and World War I. Laboratory Supplies and Suppliers. Origins of the Chemical Glassware Industry in America. Bausch Lomb Optical Co. XI Introduction to Physiological Chemistry. Chittenden and 245 the Sheffield Scientific School. Societies, Journals, and the Diversity of Biochemistry. Analysis by Color Comparison. The Duboscq Colorimeter and Its Early Uses. Modern Colorimeter. The Optical Laws of Beer-Lambert-Bouguer. Duboscq s Optical Instruments. XII Introduction. The Flexner Report and Medical School 269 Reform. Medical Chemistry, Physiological Chemistry, and Biological Chemistry. Otto Folin. Metabolic Studies at McLean Hospital. Colorimetric Methods for Blood Analysis. Nonprotein Nitrogen (NPN). Folin Joins Harvard Medical School. The Folin-Wu Protein-Free Filtrate and Other Protein Precipitants. Stanley Benedict. The Rockefeller Institute for Medical Research. Donald Dexter Van Slyke and the Rockefeller Hospital. Ivar Bang and Micromethods. Venipuncture and Blood Analysis. Evolution of the Hypodermic Syringe. Becton Dickinson and Company (1897-1997) and the Vacutainer Tube. XIII Introduction. Benedict s Reagent for Urine Glucose. 319 Analysis of Blood Glucose. Method Modifications by Folin and Benedict. A New Glucose Reagent—Alkaline Ferricyanide. Somogyi Protein-Free Filtrate. Tablets, Powders, and Dipsticks. Another New Glucose Reagent—Ortho-Toluidine. Enzymatic Methods for True Glucose. Creatine, Creatinine, and Creatinine Clearance. Uric Acid. Urea and Urease. Urea Clearance. Phenolsulphonephthalein Excretion. Bromsulphalein Retention. Blood Volume. XIV Chloride, Calcium, Phosphorus, Sodium and Potassium: 351 Introduction. Gravimetric, Titrimetric, and Colorimetric Methods. Spectroscopy. Bunsen and Kirchhoff Apply xii CONTENTS Spectral Analysis. Arc and Spark Analysis. Flame Photometry. Ion-Selective Electrodes. Atomic Absorption Spectrometry. XV Cholesterol: Introduction. Color Reactions. Reaction 377 With Digitonin. Blood Analysis: Esterified and Free Cholesterol. Reference Methods. Enzymatic Methods. Atherosclerosis, Coronary Heart Disease, and the National Cholesterol Education Program. Bilirubin: Introduction. Icterus Index. Diazo, Direct, and Indirect Reaction. Standards: Artificial and Certified. Urine Analysis and Tablet Test. Kernicterus in the Newborn. Direct Spectrophotometric Assay. XVI Enzymes: Introduction. The Catalytic Force. Ferments: 395 Organized and Unorganized. Chemical vs Vitalist Fermentation. Zymase and the Cell-Free Extract of Yeast. Enzyme Theory of Life. Protein Identity of Enzymes. Amylase. Lipase. Alkaline Phosphatase. Acid Phosphatase. Aspartate Aminotransferase and Other Enzymes. SI Units. XVII Proteins: Introduction. Classical Separation of Albumin 417 and Globulin. Salt Precipitation. Sodium Sulfate Fractionation: Euglobulin and Pseudoglobulin I and II. Improved Salt Precipitation Methods. Albumin Binding Reagents. Biuret Color Reaction. Moving Boundary Electrophoresis. Separation on Filter Paper. Visualization of Discrete Bands. Other Support Media. Refractive Index. Specific Gravity. Clot Formation: Introduction. Separation and Quantitation of Fibrinogen (Fibrin). XVIII Victor Myers and the New York Post-Graduate Medical 443 School and Hospital. Practical Chemical Analysis of Blood. St. Luke s and St. Thomas s. Hawk s Practical Physiological Chemistry. Peters and Van Slyke: Quantitative Clinical Chemistry. Photometry: Introduction. The Photoelectric Effect. Photoelectric Colorimeters (Photometers). Hoffman s Photoelectric Clinical Chemistry. Spectrophotometry: Visible and Ultraviolet. CONTENTS xiii XIX Clinical Chemistry Laboratory (1925-1960). Proficiency 465 Testing. Biochemistry Sheds Its Clinical Connection. American Association of Clinical Chemists. Foreign Societies and the International Federation. Bio-Science: The Era of Referral Chemistry. Sigma and Kit Methods. Berson, Yalow, and Radioimmunoassay. Tool-Instrument-Machine-Automation. Skeggs and the AutoAnalyzer. Factory Teaching Facility. Analyzers: Discrete Sample and Random Access. XX Pitfalls of Publication. Dangers of Laboratory Diagnosis. 503 The Laboratory: Possibilities and an Image Problem. Scientific Medicine and Overuse of the Laboratory. A New Partnership—A New Vocabulary. Looking to the Future—Cost Containment and Managed Care. New Career Opportunities for the Clinical Chemist. Conclusion. Bibliography 519 Index 533
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Four centuries of clinical chemistry
title Four centuries of clinical chemistry
title_auth Four centuries of clinical chemistry
title_exact_search Four centuries of clinical chemistry
title_full Four centuries of clinical chemistry Louis Rosenfeld
title_fullStr Four centuries of clinical chemistry Louis Rosenfeld
title_full_unstemmed Four centuries of clinical chemistry Louis Rosenfeld
title_short Four centuries of clinical chemistry
title_sort four centuries of clinical chemistry
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