Skin cancer prevention

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Veröffentlicht: New York, NY [u.a.] Informa Healthcare 2007
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Datensatz im Suchindex

_version_ 1819708288285016064
adam_text Contents Preface .... iii Contributors .... xiii 1. Photobiology of Photocarcinogenesis ........................ I David L. Mitchell and James E. Cleaver Introduction — The Problem . . . . 1 Photochemistry of DNA in the Skin .... 4 DNA Damage and Skin Cancer .... S Mechanisms of Sunlight Mutagenesis .... 10 Biochemical Pathways of Carcinogenesis .... 12 Conclusions .... 75 References .... 16 2. Etiology of Nonmelanocytic Skin Cancer ................... 21 Cara L. Benjamin and Honnavara N. Ananthaswamy Introduction .... 21 UV Damage to DNA____23 Epidemiological Evidence .... 24 Experimental Evidence .... 26 Molecular Evidence .... 28 Cellular and Molecular Mechanisms .... 34 Different Mechanisms for Different Tumor Types .... 36 Summary .... 37 References .... 37 y¡ Contents 3. Etiology and Modeling of Human Melanoma: Illuminating the Dark Pathways of a Deadly Disease ....................................... 49 Steven Kazianis and Meenhard Herlyn Introduction .... 49 Modeling Melanoma .... 54 Etiology .... 57 Conclusions and Future Directions .... 66 References .... 68 4. Vitamin D, Moderate Sun Exposure, and Health ............. 79 Michael F. Holick Evolutionary Perspective .... 79 Human Historical Perspective .... 80 Photoproduction of Vitamin D3 in Human Skin .... Si Factors That Affect the Cutaneous Synthesis of Vitamin D3 .... 84 Major Sources of Vitamin D .... 87 Endocrine, Metabolism, and Physiologic Function of Vitamin D on Calcium and Bone Health .... 88 Consequences of Vitamin D Deficiency on Calcium Metabolism and Bone Health .... 88 Autocrine Metabolism of Vitamin D and Its Physiologic Functions .... 90 Consequences of Inadequate Sun Exposure and Living at Higher Latitudes on Health .... 91 Adequate Intake Recommendations for Vitamin D and What You Really Need ____92 Prevention and Treatment of Vitamin D Deficiency .... 93 Vitamin D Deficiency Pandemic .... 95 Conclusion .... 95 References .... 97 5. Ultraviolet Radiation Risks to the Eye .................... 107 David H. Sliney Introduction .... 107 Effects from Environmental Exposure .... 108 Guidelines for Human Exposure .... 114 Conclusions .... 120 References .... 121 Appendix: Applying the UVR Exposure Limits .... 129 Contents vii 6. Histopathology Standards: Nonmelanoma Skin Cancer ....... 131 Nigel Kirkham Introduction .... 131 Squamous Cell Carcinoma .... 132 Basal Cell Carcinoma .... 136 Conclusion .... 142 References .... 143 7. Pathology of Skin Cancer with Particular Reference to Melanoma ................................ 145 David E. Elder Introduction .... 145 Malignant Melanoma .... 146 Prognostic Attributes for Melanoma .... 152 Prognostic Models for Melanoma .... 154 Molecular Pathology of Melanocytic Tumors .... 755 References .... 156 8. Epidemiology of Nonmelanocytic Skin Cancer .............. 163 Richard P. Gallagher, Tim K. Lee, and Chris D. Bajdik Introduction .... 163 Descriptive Epidemiology .... 164 Analytic Epidemiology: Host Susceptibility Factors .... 166 Analytic Epidemiology: UV Radiation Exposure .... 169 Other Factors ____171 Summary .... 172 References .... 173 9. Epidemiology of Cutaneous Malignant Melanoma ........... 179 Johan Moan, Alina Carmen Porojnicu, and Arne Dahlback Introduction .... 179 Arguments Against and for a Relationship Between Ultraviolet Radiation and Cutaneous Malignant Melanoma .... 180 Materials and Methods .... 181 Time Trends ____182 Dependency on Living Standard .... 186 Latitude Gradients .... 187 Intermittent Exposure Hypothesis .... 190 Other Factors Relevant for Cutaneous Malignant Melanoma .... 192 Conclusions .... 196 References ____197 v¡¡¡ Contents 10. Descriptive Epidemiology of Skin Cancer Incidence and Mortality .............................. 203 Mathieu Boniol, Jean-François Doré, Philippe Autier, Michel Smans, and Peter Boyle Introduction .... 203 Cutaneous Melanoma .... 203 Incidence of Cutaneous Melanoma Worldwide .... 204 Survival from Cutaneous Melanoma .... 207 Mortality from Cutaneous Melanoma .... 207 Nonmelanoma Skin Cancer .... 210 Conclusion .... 216 References .... 219 11. Molecular Epidemiology of Skin Cancer .................. 225 Rajiv Kumar Introduction .... 225 Sun Exposure and DNA Damage .... 226 UV Signature Mutations in Critical Genes .... 230 Genetic Determinants of Risk Modulation .... 232 Arsenic as a Skin Carcinogen .... 234 Conclusions .... 235 References .... 235 12. The Usefulness of Sunscreens .......................... 241 Jean-François Doré, Mathieu Boniol, Marie-Christine Chignol, and Philippe Autier Introduction .... 241 Nonmelanoma Skin Cancers .... 243 Melanoma .... 247 Sunscreen Use and Duration of Sun Exposure .... 263 Conclusion .... 271 References .... 273 13. Solaria ............................................ 279 Jean-Pierre Césarini History ____280 Technologies: How Is Artificial UV Produced? ____281 Regulation ____282 Consumer Use of Tanning Devices .... 285 Risks Linked to the Use of Solaria .... 286 Conclusions and Recommendations .... 288 References ____290 Contents ¡χ 14. Risk Groups for Skin Cancer and Aspects on Preventive Management .............................. 293 Johan Hansson and Ulrik Ringborg Introduction .... 293 High-Risk Groups for Cutaneous Melanoma .... 293 Phenotypic Characteristics .... 294 Previous Melanoma .... 296 Hereditary Factors .... 296 Management of Individuals with a High Risk of Cutaneous Malignant Melanoma .... 302 Nonmelanoma Skin Cancer .... 304 Immunosuppression and Elevated Risk for Nonmelanoma Skin Cancer .... 305 Conclusions .... 306 References .... 306 15. Behavioral Aspects of Prevention and Early Detection ....... 315 Richard Bränström Introduction .... 315 Theories of Health Behavior and Health Behavior Change .... 316 Behaviors Related to Prevention and Early Detection .... 318 Skin Cancer Prevention Using Behavioral Profiles .... 327 Conclusions .... 331 References .... 332 16. Periods-of-Life Program: Continuous Primary Prevention of Skin Cancer in Certain Age Groups ................... 339 Rüdiger Greinert, B. Volkmer, S. Welz, and Eckhard W. Breitbart Introduction .... 339 UV and Skin Cancer ____340 Periods-of-Life Program .... 340 References .... 343 17. Aims of Primary Prevention of Skin Cancer ............... 345 Karen Glanz Introduction .... 345 Target Outcomes for Primary Prevention .... 346 Population Targets and Settings for Primary Prevention .... 349 Broad Typology of Primary Prevention Strategies ------350 International Considerations .... 352 Discussion .... 354 References .... 356 x Contents 18. Screening for Melanoma .............................. 359 Alan С Geller Introduction .... 359 Rationale and Definitions for Melanoma Screening .... 360 Applications of Screening Definitions to Melanoma .... 360 Theoretical Aspects of Melanoma Screening .... 361 Defining Criteria for Successful Control Programs .... 362 Screening Recommendations for Melanoma .... 362 Identification of High-Risk Populations and Appropriate Venues for Screening and Education .... 363 Current Venues in Melanoma Screening and Education .... 364 Screening in the Primary Care Setting .... 366 Strategies to Improve Melanoma Screening and Education .... 366 References .... 371 19. Communicating the Incalculable ........................ 377 Gunilla Jarlbro The Individual s Relationship to the Risk .... 378 Media Impact on People s Assessment of Risk .... 379 Can Communication Be Used to Heighten Subjective Risk Perception? .... 381 I Suppose We Should Run an Ad Campaign? .... 382 Considerations for the Future .... 386 References .... 387 20. Sun Protection at School .............................. 389 Cecilia Boldemann and Craig Sinclair Introduction .... 389 Supportive Environment for Sun Protection in School Settings .... 390 Structural Strategies for Behavioral Modification .... 391 Synergies: Gains for Environmental Protection and Health ____401 Audits, Surveillance, and Monitoring of Policies and Behaviors .... 403 Conclusion .... 403 References .... 404 21. The ÜV Index in Practice ............................. 407 Eva Rehfuess and Craig Sinclair Introduction .... 407 Alerting People About UV Radiation .... 408 Experiences from Around the World .... 410 Contents xi Does the UV Index Influence Behavior? .... 412 Lessons Learned and Opportunities Ahead .... 414 References .... 477 22. Prevention of Malignant Melanoma: Health Economics Aspects ............................. 421 Bengt Jönsson and Ulf Staginnus Introduction .... 421 Primary Prevention .... 423 Secondary Prevention .... 424 Issues for Further Research .... 428 Conclusions .... 429 References .... 429 23. Screening for Melanoma .............................. 431 Frederick C. Beddingfield Introduction .... 431 Incidence .... 432 Mortality and Survival .... 434 Distribution of Stages at Diagnosis .... 434 Etiology and Risk Factors .... 435 Public Health Initiatives and Screening .... 437 References .... 441 Index .... 445 about the book... Coedited by the President of the European Society of Skin Cancer Prevention, this guide provides a detailed overview of the three most common forms of skin cancer — basal cell, squamous cell, and mela¬ noma — and authoritatively guides readers through current research related to the epidemiology, primary and secondary prevention, and identification of the many forms of the disease. This source offers five comprehensive sections that cover basic re¬ search, epidemiology, primary prevention, secondary prevention, and communication techniques...responds to the increasing frequency of skin cancer around the world by covering the most recent prevention strategies and public health programs to prevent disease...collects the most recent studies on the identification of risk factors for disease, and methods for early-stage disease detection...emphasizes the importance of international standards in the histopathology of skin cancer...and bridges developments in translational research, epidemiology, and molecular biology to determine effective methods of disease prevention. about the editors... ULRIK RINGBORG is Professor, Department of Oncology-Pathology, Karolinska Institute and Director, Cancer Center Karolinska, Karolinska University Hospital Solna, Stockholm, Sweden. YVONNE BRANDBERG is Associate Professor, Department of Oncology-Pathology, Karolinska Institute and Karolinska University Hospital Solna, Stockholm, Sweden. ECKHARD W. BREITBART is Head of the Center of Dermatology, Buxtehude, Germany. He is a former President of the European Society of Skin Cancer Prevention. RUDIGER GREINERT is Professor, Center of Dermatology, Buxtehude, Germany.
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record_format marc
spellingShingle Skin cancer prevention
Skin Cancer Prevention
Skin Neoplasms prevention & control
Risk Factors
Skin Neoplasms epidemiology
Prävention (DE-588)4076308-0 gnd
Hautkrebs (DE-588)4140169-4 gnd
subject_GND (DE-588)4076308-0
(DE-588)4140169-4
title Skin cancer prevention
title_auth Skin cancer prevention
title_exact_search Skin cancer prevention
title_full Skin cancer prevention ed. by Ulrik Ringborg ...
title_fullStr Skin cancer prevention ed. by Ulrik Ringborg ...
title_full_unstemmed Skin cancer prevention ed. by Ulrik Ringborg ...
title_short Skin cancer prevention
title_sort skin cancer prevention
topic Skin Cancer Prevention
Skin Neoplasms prevention & control
Risk Factors
Skin Neoplasms epidemiology
Prävention (DE-588)4076308-0 gnd
Hautkrebs (DE-588)4140169-4 gnd
topic_facet Skin Cancer Prevention
Skin Neoplasms prevention & control
Risk Factors
Skin Neoplasms epidemiology
Prävention
Hautkrebs
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