Imaging and the aging brain
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| Sprache: | English |
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Boston, Mass
Blackwell
2007
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| Schriftenreihe: | Annals of the New York Academy of Sciences
1097 |
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Datensatz im Suchindex
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| adam_text | ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Volume 1097
February 2007
IMAGING AND THE AGING BRAIN
Editors
Mony J. de Leon, Donald A. Snider, and
Howard Federoff
This volume is the result of a meeting entitled Imaging and the Aging Brain, sponsored
by the New York Academy of Sciences and held on May 16 17, 2006 in New York City.
CONTENTS
Foreword. By Mony J. de Leon xi
Part I. In Vivo Imaging of Molecules, Cells, and Networks in Aging and
Animal Models of Alzheimer s Disease
Making New Memories: The Role of the Hippocampus in New Associative
Learning. By Wendy A. Suzuki 1
Anatomical and Functional Phenotyping of Mice Models of Alzheimer s
Disease by MR Microscopy. By Helene Benveniste, Yu Ma,
Jasbeer Dhawan, Andrew Gifford, S. David Smith, Igor Feinstein,
Congwu Du, Samuel C. Grant, and Patrick R. Hof 12
Various Dendritic Abnormalities Are Associated with Fibrillar Amyloid
Deposits in Alzheimer s Disease. By Jaime Grutzendler,
Kathryn Helmin, Julia Tsai, and Wen Biao Gan 30
Two Photon Imaging of Astrocytic Ca2+ Signaling and the Microvasculature
in Experimental Mice Models of Alzheimer s Disease. By
Takahiro Takano, Xiaoning Han, Rashid Deane,
Berislav Zlokovic, and Maiken Nedergaard 40
Synaptic and Mitochondrial Morphometry Provides Structural Correlates of
Successful Brain Aging. By Carlo Bertoni Freddari,
Patrizia Fattorettl Belinda Giorcjetti, Yessica Grossi,
Marta Balietti, Tiziana Casoli. Giuskppina di Stefano, and
Gemma Perretta 51
Impaired Recognition Memory and Decreased Prefrontal Cortex Spine
Density in Aged Female Rats. By MauREen Wallace,
Maya Frankfurt, adolfo Arellanos, Tomoko Inagaki, and
Victoria Luine 54
Alzheimer Amyloid ß Peptide A ß25 35 Blocks Adenylate Cyclase Mediated
Forms of Hippocampal Long Terrn Potentiation. Bv Blaine E. Bisel,
Kristen M. Henkins, and Karen D. Parfitt 58
Age Related Changes in Neuronal Susceptibility to Damage: Comparison of
the Retinal Ganglion Cells of Young and Old Mice Before and After
Optic Nerve Crush. By Ai Ling Wang, Ming Yuan, and
Arthur H. Neufeld 64
Part II. In Vivo Imaging of Human Aging and the Transition to
Cognitive Impairment
Top Down Modulation and Normal Aging. Bv Adam Gazzaley
and Mark D Esposito 67
Brain Aging and Its Modifiers: Insights from in Vivo Neuromorphometry
and Susceptibility Weighted Imaging. Bv Naftali Raz,
Karen M. Rodrigue, and E. Mark Haacke 84
Linking Brain Imaging and Genomics in the Study of Alzheimer s Disease
and Aging. By Eric M. Reiman 94
Imaging and CSF Studies in the Preclinical Diagnosis of Alzheimer s
Disease. By M. J. de Leon, L. Mosconi, K Blennow, S. DeSanti,
R. Zinkowski, P. D. Mehta, D. Pratico, W. Tsui, L. A Saint Louis,
L. Sobanska, M. Brys, Y. Li, K. Rich, J. Rinne, and H. Rusinek 114
Funct OIjal MRI Studies of Associative Encoding in Normal Aging,
Mild Cognitive Impairment, and Alzheimer s Disease. By
keisa Sperling 146
Quantitative EEG and Electromagnetic Brain Imaging in Aging and in the
Evolution of Dementia. By Leslie S. Prichep ........ 156
t I]5 IA 85380 SPECT Imaging of ß2 Nicotinic Acetylcholine Receptor
Availabihty in the Aging Human Brain. Bv Effie M. Mitsis,
KELLY K COSGROVE, JULIE K. StaLEY, ERIN B. FRÖHLICH, FREDERIC BOIS,
oillls D. Tamagnan, Kristina M Estok, John P. Seibyl, and
Christopher h. Van Dyck 168
Role of Aerobic Fitness and Aging on Cerebral White Matter Integrity. By
Bonita L. Marks, David J. Madden Barbara Bucur
James M. Provenzale, Leonard E. white, Roberto Cabeza, and
Scott A. Huettel 171
Age Related Changes in Nociceptive Processing in the Human Brain. By
Raimi L. Quiton, Steven R. Roys, Juchen Zhuo, Michael L. Keaser,
KAO P. GULLAPALLl, AND JOEL D GREENSPAN 175
Magnetic Resonance Spectroscopy and Environmental Toxicant Exposure. By
Marc G. Weisskopf 179
Part III. Diagnostic Applications of Imaging to Alzheimers Disease
Tracking Alzheimers Disease. By Paul M. Thompson, Kiralee M. Hayashi,
Rebecca A. Dutton, Ming Chang Chiang, Alex D. Leow,
Elizabeth R. Sowell, Greig de Zubicaray, James T. Becker,
Oscar L. Lopez, Howard J. Aizenstein, and Arthur W. Toga 183
Shifting Paradigms in Dementia: Toward Stratification of Diagnosis and
Treatment Using MRI. By Wiesje M. van der Flier,
Frederik Barkhof, and Philip Scheltens 215
Imaging Guided Microarray: Isolating Molecular Profiles That Dissociate
Alzheimer s Disease from Normal Aging. By Ana Carolina Pereira,
William Wu, and Scott A. Small 225
Fibrillar and Oligomeric ß Amyloid as Distinct Local Biomarkers for
Alzheimer s Disease. By Michael C. Montalto, Gill Farrar, and
Cristina Tan Hehir 239
Diffusion Tensor Imaging of Normal Appearing White Matter and Its
Correlation with Cognitive Functioning in Mild Cognitive Impairment
and Alzheimer s Disease. By Juebin Huang and
Alexander P. Auchus 259
Enhanced Ryanodine Mediated Calcium Release in Mutant PSl Expressing
Alzheimer s Mouse Models. By Gracf. E. Stutzmann, Ian Smith,
Antonella Caccamo, Salvatore Oddo, Ian Parker, and
Frank Laferla 265
Prospects for Prediction: Ethics Analysis of Neuroimaging in Alzheimer s
Disease. By J. Illes, A. Rosen, M. Greicius, and E. Racine 278
Index of Contributors 297
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| physical | XII, 298 S. Ill., graph. Darst. |
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| series2 | Annals of the New York Academy of Sciences |
| spellingShingle | Imaging and the aging brain Annals of the New York Academy of Sciences Alter (DE-588)4001446-0 gnd Hirnfunktion (DE-588)4159930-5 gnd Hirnfunktionsstörung (DE-588)4133771-2 gnd Alzheimerkrankheit (DE-588)4112510-1 gnd Bildgebendes Verfahren (DE-588)4006617-4 gnd |
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| title | Imaging and the aging brain |
| title_auth | Imaging and the aging brain |
| title_exact_search | Imaging and the aging brain |
| title_full | Imaging and the aging brain ed. by Mony J. de Leon ... |
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| title_full_unstemmed | Imaging and the aging brain ed. by Mony J. de Leon ... |
| title_short | Imaging and the aging brain |
| title_sort | imaging and the aging brain |
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| topic_facet | Alter Hirnfunktion Hirnfunktionsstörung Alzheimerkrankheit Bildgebendes Verfahren Konferenzschrift 2006 New York, NY |
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