Inflammatory bowel disease translation from basic research to clinical practice ; proceedings of the Falk Symposium 140 held in Dubrovnik, Croatia, May 7 - 8, 2004

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Veröffentlicht: Dordrecht Springer 2005
Schriftenreihe:Falk Symposium 140
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Datensatz im Suchindex

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adam_text Contents List of principal contributors ix Preface xiii SECTION I: GENETICS Chair: DP Jewell, Z Tulassay 1 Molecular classification of inflammatory bowel disease Τ Ahmad 3 2 NOD proteins and defence against microbial infection DJPhilpott 17 3 Pharmacogenetics of inflammatory bowel disease therapy M Schwab, E Schaeffeler 24 4 Genotypes and phenotypes in clinical practice S Vermeire 34 SECTION II: MICROBIOLOGY Chair: J-F Colombel, S Kolacek 5 Chronic inflammatory disorders, the gut and the Old Friends hypothesis GAW Rook, L Rosa Brunet 43 6 Innate immune receptors and inflammatory bowel disease E Cario, DK Podolsky 59 7 Manipulation of enteric flora in clinical practice MA Kamm 66 CONTENTS SECTION III: IMMUNOREGULATION: NOVEL THERAPEUTIC AGENTS Chair: R Löfberg, M Lukáš 8 Lymphocyte integrine and the pathogenesis of experimental colitis KP Pavlick, MB Grisham 75 9 Role of cytokines and their receptors in inflammatory bowel diseases H Tilg 83 10 State-of-the-art: targeting immunoregulation - biologicals WJ Sandborn 90 SECTION IV: MANIPULATION OF THE ENVIRONMENT Chair: M Gassull, E Butruk 11 Environmental epidemiology A Timmer 101 12 Understanding the opposite effects of smoking in inflammatory bowel disease J Cosnes 112 13 Microparticles: a link between modern life and inflammatory bowel disease? L Pele, J J Powell 123 14 Are we able to treat inflammatory bowel disease with diet? T Nie Suibhne, C O Morain and M O Sullivan 138 SECTION V: NEW DIAGNOSTIC TOOLS Chair: RW Stockbriigger, Z Krastev 15 Novel endoscopie diagnostic developments - bioendoscopy GNJ Tytgat 149 16 Cross-sectional imaging in inflammatory bowel disease К Turetschek 154 17 State-of-the-art: the transparent abdomen P Asbach, P Rogalla, В Hamm 158 CONTENTS SECTION VI: MECHANISM OF ACTION OF ESTABLISHED DRUGS Chair: RN Fedorak, Ρ Michetti 18 Apoptosis as a target MFNeurath 167 19 Mechanisms of action of conventional drugs in inflammatory bowel disease LJEgan 173 20 Optimizing the use of current drugs for inflammatory bowel disease GD Haens 180 SECTION VII: THE DIFFICULT CASES OF CROHN S DISEASE Chair: R Caprilli, S Bar-Meir 21 Diffuse jejunoileitis in an adolescent S Cukovic-Cavka, B Vucelic 189 22 Diffuse jejunoileitis in the adolescent patient MCDubinsky 196 23 Current methods of bowel-sparing surgery in Crohn s disease A Fichera, RD Hurst, F Michelassi 202 24 Mechanisms of steroid-refractory disease D Franchimont 220 25 Management of perianal Crohn s disease SS Hanauer 234 SECTION VIII: THE DIFFICULT CASES OF ULCERATIVE COLITIS Chair: С Gasché, S Markovic 26 A case of refractory proctitis W Miehsler 243 27 Inflammatory bowel diseases and innate immunity J Wehkamp, К Fellermann and EF Stange 249 28 Biology of cancer in ulcerative colitis and consequences for chemoprevention CR Boland, С Gasché, G Marra, CL Chang 259 CONTENTS 29 Therapeutic strategy in ulcerative colitis - 2004 D Rachmilewitz 270 Index 275 About the Book The amount of information on the pathogenesis of inflammatory bowel disease is growing rapidly. This is reflected by a continuous increase in the number of papers presented at international Gl meetings. To make things more difficult for practicing physicians, there is also a large number of new clinical trials being published which require periodical critical reviews and recommendations. Faced with these issues, the scientific commitee of the Falk Symposium No. 140 decided to take a different approach and to apply a novel format that is reflected in the title of the Symposium: Translation from basic research to clinical practice . This book contains the proceedings of that Symposium, held in Dubrovnik, Croatia, on May 7-8, 2004. The sections are designed so that they start with the information from basic sciences on different aspects of these complex diseases and further lead to their clinical implications. Special attention is paid to the mechanisms of actions of established drugs. The last two sections are clinically oriented and focus on the most difficult aspects of both Crohn s disease and ulcerative colitis. This format provides state-of-the-art chapters by leading experts in the field and at the same time up-to-date information on the clinical application of the new knowledge.
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spellingShingle Inflammatory bowel disease translation from basic research to clinical practice ; proceedings of the Falk Symposium 140 held in Dubrovnik, Croatia, May 7 - 8, 2004
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title Inflammatory bowel disease translation from basic research to clinical practice ; proceedings of the Falk Symposium 140 held in Dubrovnik, Croatia, May 7 - 8, 2004
title_auth Inflammatory bowel disease translation from basic research to clinical practice ; proceedings of the Falk Symposium 140 held in Dubrovnik, Croatia, May 7 - 8, 2004
title_exact_search Inflammatory bowel disease translation from basic research to clinical practice ; proceedings of the Falk Symposium 140 held in Dubrovnik, Croatia, May 7 - 8, 2004
title_full Inflammatory bowel disease translation from basic research to clinical practice ; proceedings of the Falk Symposium 140 held in Dubrovnik, Croatia, May 7 - 8, 2004 ed. by J.-F. Colombel ...
title_fullStr Inflammatory bowel disease translation from basic research to clinical practice ; proceedings of the Falk Symposium 140 held in Dubrovnik, Croatia, May 7 - 8, 2004 ed. by J.-F. Colombel ...
title_full_unstemmed Inflammatory bowel disease translation from basic research to clinical practice ; proceedings of the Falk Symposium 140 held in Dubrovnik, Croatia, May 7 - 8, 2004 ed. by J.-F. Colombel ...
title_short Inflammatory bowel disease
title_sort inflammatory bowel disease translation from basic research to clinical practice proceedings of the falk symposium 140 held in dubrovnik croatia may 7 8 2004
title_sub translation from basic research to clinical practice ; proceedings of the Falk Symposium 140 held in Dubrovnik, Croatia, May 7 - 8, 2004
topic Chronische Darmentzündung (DE-588)4273697-3 gnd
topic_facet Chronische Darmentzündung
Konferenzschrift 2004 Dubrovnik
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