Advances in systems biology
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| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Kluwer Acad. / Plenum Publ.
2004
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| Schriftenreihe: | Advances in experimental medicine and biology
547 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
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| 245 | 1 | 0 | |a Advances in systems biology |c ed. by Lee K. Opresko ... |
| 264 | 1 | |a New York [u.a.] |b Kluwer Acad. / Plenum Publ. |c 2004 | |
| 300 | |a IX,108 S., [9] Bl. |b zahlr. Ill. und graph. Darst. | ||
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| 490 | 1 | |a Advances in experimental medicine and biology |v 547 | |
| 500 | |a Includes bibliographical references | ||
| 650 | 4 | |a Systèmes biologiques | |
| 650 | 4 | |a Biological systems | |
| 650 | 4 | |a Computational Biology |v Congresses | |
| 650 | 4 | |a Models, Biological |v Congresses | |
| 650 | 4 | |a Molecular Biology |v Congresses | |
| 650 | 4 | |a Signal Transduction |v Congresses | |
| 650 | 4 | |a Systems biology | |
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Datensatz im Suchindex
| _version_ | 1819636423828963328 |
|---|---|
| adam_text | TABLE OF CONTENTS j
1. INTRODUCTION 1
About the Northwest Symposium for Systems Biology I
Lee K. Opresko, H. Steven Wiley, Pacific Northwest National Laboratory j
COMPLEX MICROBIAL SYSTEMS
2. HIGH THROUGHPUT TECHNIQUES FOR ANALYZING COMPLEX
BACTERIAL COMMUNITIES 5
David A. Stahl, University of Washington
2.1. THE TALK 6
2.2. ENVIRONMENT BASED RESEARCH: A HOLISTIC APPROACH 7
2.3. TECHNOLOGY DEVELOPMENTS—DNA MICROARRAY
TECHNOLOGY 11
2.4. ACKNOWLEDGMENTS 17
2.5. REFERENCES 17
COMPUTATIONAL METHODS
3. A SYSTEMS APPROACH TO DISCOVERING SIGNALING AND
REGULATORY PATHWAYS—or how to digest large interaction
networks into relevant pieces 21
Trey Ideker, Whitehead Institute for Biomedical Research
3.1. INTRODUCTION 21
3.2. INTEGRATING INTERACTIONS AND MOLECULAR STATES 22
3.3. AUTOMATICALLY EXTRACTING INTERACTION PATHWAYS
FROM THE NETWORK 23
3.4 SCREENING FOR ACTIVE PATHWAYS RESPONDING TO
GALACTOSE GENE PERTURBATIONS 25
3.5 PATHWAYS RESPONDING TO DNA DAMAGE AS REVEALED
BY HIGH THROUGHPUT PHENOTYPIC ASSAYS 27
vii
viii TABLE OF CONTENTS
3.6. SUMMARY 27
3.7. ACKNOWLEDGMENTS 29
3.8. REFERENCES 29
4. GENOME FUNCTION—A VIRUS WORLD VIEW 31
John Yin, University of Wisconsin Madison
4.1. INTRODUCTION 31
4.2. THE T7 DEVELOPMENT PROCESS 33
4.3. FROM EQUATIONS TO INTEGRATED DYNAMICS 34
4.4. INFERENCE TOOLS 37
4.5. NATURE VERSUS NURTURE 40
4.6. ACKNOWLEDGMENTS 45
4.7. REFERENCES 45
MOLECULAR MACHINES: MULTIPROTEIN COMPLEXES
5. INTRACELLULAR PROTEOLYSIS AND PROTEASOMES 49
Martin C. Rechsteiner, University of Utah
5.1. INTRODUCTION 49
5.2. THE 20S PROTEASOME 50
5.3. THE 26S PROTEASOME 52
5.4. PROTEASOME ACTIVATORS 54
5.5. REGS 55
5.6. PA200 55
5.7. ecm29 or golgiPA 57
5.8. SUMMARY 57
5.9. REFERENCES 57
6. CONFORMATIONAL SWITCHING IN MUSCLE 61
Piotr Fajer, Florida State University
6.1. INTRODUCTION 61
6.2. SPECTROSCOPIC TECHNIQUES IN MUSCLE CONTRACTION 62
6.3. STRUCTURE OF THE INHIBITORY REGION OF TROPONIN 68
6.4. ORIENTATION AND DYNAMICS OF THE MYOSIN HEAD 73
6.5. ACKNOWLEDGMENTS 79
6.6. REFERENCES 79
TABLE OF CONTENTS ix
GENE REGULATORY NETWORKS
7. THE INTRICATE WORKINGS OF A BACTERIAL EPIGENETIC
SWITCH 83
David Low, University of California at Santa Barbara
7.1. INTRODUCTION 84
7.2. MODEL 84
7.2.1 Data Supporting the Core Switch Model 85
7.3. BEYOND THE CORE SWITCH: ENVIRONMENTAL EFFECTS
ON PAP PHASE VARIATION 88
7.4. ACKNOWLEDGMENTS 89
7.5. REFERENCES 89
8. YEAST SIGNAL TRANSDUCTION: REGULATION AND
INTERFACE WITH CELL BIOLOGY 91
George F. Sprague, University of Oregon
8.1. INTRODUCTION 91
8.2. SIGNALING SPECIFICITY 92
8.3. STE20 INTERFACE WITH CELL BIOLOGY 101
8.4. SUMMARY 103
8.5. ACKNOWLEDGMENTS 104
8.6. REFERENCES 104
INDEX 107
|
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| dewey-ones | 571 - Physiology & related subjects |
| dewey-raw | 571 |
| dewey-search | 571 |
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| dewey-tens | 570 - Biology |
| discipline | Biologie |
| format | Book |
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| genre | (DE-588)1071861417 Konferenzschrift 2002 Richland Wash. gnd-content |
| genre_facet | Konferenzschrift 2002 Richland Wash. |
| id | DE-604.BV019342265 |
| illustrated | Illustrated |
| indexdate | 2024-12-23T17:41:50Z |
| institution | BVB |
| isbn | 0306483149 |
| language | English |
| lccn | 2003068653 |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-012806734 |
| oclc_num | 53840108 |
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| owner | DE-12 |
| owner_facet | DE-12 |
| physical | IX,108 S., [9] Bl. zahlr. Ill. und graph. Darst. |
| publishDate | 2004 |
| publishDateSearch | 2004 |
| publishDateSort | 2004 |
| publisher | Kluwer Acad. / Plenum Publ. |
| record_format | marc |
| series | Advances in experimental medicine and biology |
| series2 | Advances in experimental medicine and biology |
| spellingShingle | Advances in systems biology Advances in experimental medicine and biology Systèmes biologiques Biological systems Computational Biology Congresses Models, Biological Congresses Molecular Biology Congresses Signal Transduction Congresses Systems biology Biologisches System (DE-588)4122930-7 gnd Systembiologie (DE-588)4809615-5 gnd |
| subject_GND | (DE-588)4122930-7 (DE-588)4809615-5 (DE-588)1071861417 |
| title | Advances in systems biology |
| title_auth | Advances in systems biology |
| title_exact_search | Advances in systems biology |
| title_full | Advances in systems biology ed. by Lee K. Opresko ... |
| title_fullStr | Advances in systems biology ed. by Lee K. Opresko ... |
| title_full_unstemmed | Advances in systems biology ed. by Lee K. Opresko ... |
| title_short | Advances in systems biology |
| title_sort | advances in systems biology |
| topic | Systèmes biologiques Biological systems Computational Biology Congresses Models, Biological Congresses Molecular Biology Congresses Signal Transduction Congresses Systems biology Biologisches System (DE-588)4122930-7 gnd Systembiologie (DE-588)4809615-5 gnd |
| topic_facet | Systèmes biologiques Biological systems Computational Biology Congresses Models, Biological Congresses Molecular Biology Congresses Signal Transduction Congresses Systems biology Biologisches System Systembiologie Konferenzschrift 2002 Richland Wash. |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=012806734&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000003102 |
| work_keys_str_mv | AT opreskolee advancesinsystemsbiology |