Impact of nonlinear heat transfer on temperature control in regional hyperthermia

Abstract: "We describe an optimization process specially designed for regional hyperthermia of deep seated tumors in order to achieve desired steady-state temperature distributions. A nonlinear three-dimensional heat transfer model based on temperature-dependent blood perfusion is applied to pr...

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Hauptverfasser: Lang, Jens (VerfasserIn), Erdmann, Bodo (VerfasserIn), Seebaß, Martin (VerfasserIn)
Format: Buch
Sprache:English
Veröffentlicht: Berlin Konrad-Zuse-Zentrum für Informationstechnik 1997
Schriftenreihe:Preprint SC / Konrad-Zuse-Zentrum für Informationstechnik Berlin 1997,73
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245 1 0 |a Impact of nonlinear heat transfer on temperature control in regional hyperthermia  |c J. Lang ; B. Erdmann ; M. Seebass 
264 1 |a Berlin  |b Konrad-Zuse-Zentrum für Informationstechnik  |c 1997 
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520 3 |a Abstract: "We describe an optimization process specially designed for regional hyperthermia of deep seated tumors in order to achieve desired steady-state temperature distributions. A nonlinear three-dimensional heat transfer model based on temperature-dependent blood perfusion is applied to predict the temperature. Using linearly implicit methods in time and adaptive multilevel finite elements in space, we are able to integrate efficiently the instationary nonlinear heat equation with high accuracy. Optimal heating is obtained by minimizing an integral object function which measures the distance between desired and model predicted temperatures. A sequence of minima is calculated from successively improved constant-rate perfusion models employing a damped Newton method in an inner iteration. We compare temperature distributions for two individual patients calculated on coarse and fine spatial grids and present numerical results of optimizations for a Sigma 60 Applicator of the BSD 2000 Hyperthermia System." 
650 4 |a Mathematisches Modell 
650 4 |a Cancer 
650 4 |a Heat  |x Physiological effect  |x Mathematical models 
650 4 |a Heat  |x Transmission 
650 4 |a Mathematical optimization 
700 1 |a Erdmann, Bodo  |e Verfasser  |4 aut 
700 1 |a Seebaß, Martin  |e Verfasser  |4 aut 
810 2 |a Konrad-Zuse-Zentrum für Informationstechnik Berlin  |t Preprint SC  |v 1997,73  |w (DE-604)BV004801715  |9 1997,73 
943 1 |a oai:aleph.bib-bvb.de:BVB01-010361014 

Datensatz im Suchindex

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author Lang, Jens
Erdmann, Bodo
Seebaß, Martin
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Seebaß, Martin
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bvnumber BV017190103
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ctrlnum (OCoLC)39980977
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publishDate 1997
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series2 Preprint SC / Konrad-Zuse-Zentrum für Informationstechnik Berlin
spelling Lang, Jens Verfasser aut
Impact of nonlinear heat transfer on temperature control in regional hyperthermia J. Lang ; B. Erdmann ; M. Seebass
Berlin Konrad-Zuse-Zentrum für Informationstechnik 1997
22 S. Ill., graph. Darst.
txt rdacontent
n rdamedia
nc rdacarrier
Preprint SC / Konrad-Zuse-Zentrum für Informationstechnik Berlin 1997,73
Abstract: "We describe an optimization process specially designed for regional hyperthermia of deep seated tumors in order to achieve desired steady-state temperature distributions. A nonlinear three-dimensional heat transfer model based on temperature-dependent blood perfusion is applied to predict the temperature. Using linearly implicit methods in time and adaptive multilevel finite elements in space, we are able to integrate efficiently the instationary nonlinear heat equation with high accuracy. Optimal heating is obtained by minimizing an integral object function which measures the distance between desired and model predicted temperatures. A sequence of minima is calculated from successively improved constant-rate perfusion models employing a damped Newton method in an inner iteration. We compare temperature distributions for two individual patients calculated on coarse and fine spatial grids and present numerical results of optimizations for a Sigma 60 Applicator of the BSD 2000 Hyperthermia System."
Mathematisches Modell
Cancer
Heat Physiological effect Mathematical models
Heat Transmission
Mathematical optimization
Erdmann, Bodo Verfasser aut
Seebaß, Martin Verfasser aut
Konrad-Zuse-Zentrum für Informationstechnik Berlin Preprint SC 1997,73 (DE-604)BV004801715 1997,73
spellingShingle Lang, Jens
Erdmann, Bodo
Seebaß, Martin
Impact of nonlinear heat transfer on temperature control in regional hyperthermia
Mathematisches Modell
Cancer
Heat Physiological effect Mathematical models
Heat Transmission
Mathematical optimization
title Impact of nonlinear heat transfer on temperature control in regional hyperthermia
title_auth Impact of nonlinear heat transfer on temperature control in regional hyperthermia
title_exact_search Impact of nonlinear heat transfer on temperature control in regional hyperthermia
title_full Impact of nonlinear heat transfer on temperature control in regional hyperthermia J. Lang ; B. Erdmann ; M. Seebass
title_fullStr Impact of nonlinear heat transfer on temperature control in regional hyperthermia J. Lang ; B. Erdmann ; M. Seebass
title_full_unstemmed Impact of nonlinear heat transfer on temperature control in regional hyperthermia J. Lang ; B. Erdmann ; M. Seebass
title_short Impact of nonlinear heat transfer on temperature control in regional hyperthermia
title_sort impact of nonlinear heat transfer on temperature control in regional hyperthermia
topic Mathematisches Modell
Cancer
Heat Physiological effect Mathematical models
Heat Transmission
Mathematical optimization
topic_facet Mathematisches Modell
Cancer
Heat Physiological effect Mathematical models
Heat Transmission
Mathematical optimization
volume_link (DE-604)BV004801715
work_keys_str_mv AT langjens impactofnonlinearheattransferontemperaturecontrolinregionalhyperthermia
AT erdmannbodo impactofnonlinearheattransferontemperaturecontrolinregionalhyperthermia
AT seebaßmartin impactofnonlinearheattransferontemperaturecontrolinregionalhyperthermia