Drug nucleic acid interactions
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| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
San Diego [u.a.]
Acad. Press
2001
|
| Schriftenreihe: | Methods in enzymology
340 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
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| 245 | 1 | 0 | |a Drug nucleic acid interactions |c ed. by Jonathan B. Chaires ... |
| 264 | 1 | |a San Diego [u.a.] |b Acad. Press |c 2001 | |
| 300 | |a XXXIV, 705 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
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| 490 | 1 | |a Methods in enzymology |v 340 | |
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Datensatz im Suchindex
| DE-BY-TUM_call_number | 0302 CHE 825f 03.1955 A 741 |
|---|---|
| DE-BY-TUM_katkey | 1219182 |
| DE-BY-TUM_location | 03 |
| DE-BY-TUM_media_number | 040030077284 |
| DE-BY-UBR_call_number | 88/WC 4355 C719 |
| DE-BY-UBR_katkey | 3194791 |
| DE-BY-UBR_location | 88 |
| DE-BY-UBR_media_number | 069030976774 |
| _version_ | 1822682349639303168 |
| adam_text | Table of Contents
Contributors to Volume 340 ix
Preface xiii
Volume in Series xv
Section I. Biophysical Approaches
1. Analysis and Interpretation of Ligand DNA Jonathan B. CHAIRES 3
Binding Isotherms
2. Surface Plasmon Resonance Biosensor Tina M. Davis and
Analysis of RNA Small Molecule W. David Wilson 22
Interactions
3. Simultaneous Measurement of Binding Steven M. Zeman and
Constants and Unwinding Angles Donald M. Crothers 51
by Gel Electrophoresis
4. Linear and Circular Dichroism of MAGDALENA ERIKSSON AND
Drug Nucleic Acid Complexes BENGT Norden 68
5. Rapid Screening of Structurally Selective JlNSONG Ren and
Ligand Binding to Nucleic Acids JONATHAN B. CHAIRES 99
6. Calorimetric Techniques in the Study of Ihtshamul Haq,
High Order DNA Drug Interactions BABUR Z. Chowdhry, and
Terence C. Jenkins 109
7. Volume Changes Accompanying Interaction LUIS A. MARKY,
of Ligands with Nucleic Acids DONALD W. KuPKE, and
Besik I. Kankia 149
8. Calculating Sequence Dependent Melting ALBERT S. Benight,
Stability of Duplex DNA Oligomers and PETR PANCOSKA,
Multiplex Sequence Analysis by Graphs RICHARD OWCZARZY,
Peter M. Vallone,
Jaroslav Nesetril, and
Peter V. Riccelli 165
V
Vi TABLE OF CONTENTS 9. Thermal Denaturation as Tool to Study Charles H. Spink and
DNA Ligand Interactions SUSAN E. WELLMAN 193
10. Kinetics of Binding of Hoechst Dyes to DNA SOPHIA Y. BREUSEGEM,
Studied by Stopped Flow Fluorescence FRANK G. LOONT1ENS,
Techniques PETER REGENFUSS, AND
Robert M. Clegg 212
11. Scanning Force Microscopy of Nucleic PETER T. LlLLEHEI AND
Acid Complexes Lawrence A. Bottomley 234
12. Nuclear Magnetic Resonance Studies of ANDREW N. LANE 252
Drug DNA Complexes in Solution
13. X Ray Crystallography of DNA Drug Mary ELIZABETH PEEK AND
Complexes Loren Dean Williams 282
14. Molecular Modeling of Drug DNA JOHN O. TRENT 290
Complexes: An Update
Section II. Chemical and Molecular Biological Approaches
15. Peptide Nucleic Acid Targeting of PETER E. NIELSEN 329
Double Stranded DNA
16. Drug Interaction with Triple Helical Nucleic CHRISTOPHE ESCUDE,
Acids THERESE GARESTIER, AND
Jian Sheng Sun 340
17. Measurement of Covalent Drug DNA Inter Claire J. McGurk,
actions at the Nucleotide Level in Cells at Peter J. McHUGH,
Pharmacologically Relevant Doses Michael J. Tilby,
Keith A. Grimaldi, and
John A. Hartley 358
18. Targeting DNA through Covalent Interactions David E. Graves 377
of Reversible Binding Drugs
19. Chemical Cross Linking of Drugs to DNA RYAN A. LUCE AND
Paul B. Hopkins 396
20. High Resolution Footprinting Studies of KEITH R. FOX AND
Drug DNA Complexes Using Chemical Michael J. Waring 412
and Enzymatic Probes
21. Drug RNA Footprinting Mark P. McPlKE,
Jerry Goodisman, and
James C. Dabrowiak 431
TABLE OF CONTENTS vii
22. Footprinting Methods for Analysis of JOHN W. Trauger AND
Pyrrole Imidazole Polyamide/DNA Peter B. Dervan 450
Complexes
23. High Resolution Transcription Assay for DON R. Phillips,
Probing Drug DNA Interactions at SUZANNE M. CUTTS,
Individual Drug Sites CARLEEN M. Cullinane,
and Donald M. Crothers 466
24. Use of DNA Molecules Substituted with CHRISTIAN Bailly and
Unnatural Nucleotides to Probe Specific MICHAEL J. Waring 485
Drug DNA Interactions
25. Drug Interactions with Nucleosomes and JOSE PORTUGAL 503
Chromatin
26. Locating Cobalt Binding Sites on DNA ANGELA M. SNOW AND
Using Restriction Endonucleases RICHARD D. SHEARDY 519
27. Exploiting Anthracycline Scaffold for WALDEMAR PRIEBE,
Designing DNA Targeting Agents Izabela Fokt,
Teresa Przewloka,
Jonathan B. Chaires,
Jose Portugal, and
John O. Trent 529
28. Design, Synthesis, and Characterization VLADIMIR M. GUELEV,
of Polyintercalating Ligands Mark S. Cubberley,
Meredith M. Murr,
R. Scott Lokey, and
Brent L. Iverson 556
Section III. Enzymology and Biological Approaches
29. Targeting Telomeres and Telomerase DAEKYU SUN AND
Laurence H. Hurley 573
30. Rapid, High Throughput Engineering of Mark ISALAN and
Sequence Specific Zinc Finger YEN CHOO 593
DNA Binding Proteins
31. DNA Relaxation and Cleavage Assays to CHRISTIAN Bailly 610
Study Topoisomerase I Inhibitors
32. In Vitro Human Immunodeficiency Virus CHRISTOPHE MARCHAND,
Type 1 Integrase Assays Nouri Neamati, and
Yves Pommier 624
viii TABLE OF CONTENTS
33. Use of Xenopus Egg Extracts to Study Effects ASMITA KUMAR,
of DNA Binding Drugs on Chromatin HONGZHI Xu, and
Assembly, Nuclear Assembly, and DNA GREGORY H. LENO 634
Replication
Author Index 655
Subject Index 689
|
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| discipline | Chemie / Pharmazie Biologie Medizin |
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| genre_facet | Aufsatzsammlung |
| id | DE-604.BV013874286 |
| illustrated | Illustrated |
| indexdate | 2024-12-23T15:43:08Z |
| institution | BVB |
| isbn | 0121822419 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-009491114 |
| oclc_num | 231881623 |
| open_access_boolean | |
| owner | DE-20 DE-355 DE-BY-UBR DE-19 DE-BY-UBM DE-91G DE-BY-TUM DE-29T DE-12 DE-703 DE-188 DE-578 DE-B768 |
| owner_facet | DE-20 DE-355 DE-BY-UBR DE-19 DE-BY-UBM DE-91G DE-BY-TUM DE-29T DE-12 DE-703 DE-188 DE-578 DE-B768 |
| physical | XXXIV, 705 S. Ill., graph. Darst. |
| publishDate | 2001 |
| publishDateSearch | 2001 |
| publishDateSort | 2001 |
| publisher | Acad. Press |
| record_format | marc |
| series | Methods in enzymology |
| series2 | Methods in enzymology |
| spellingShingle | Drug nucleic acid interactions Methods in enzymology Arzneimittel (DE-588)4003115-9 gnd Nucleinsäuren (DE-588)4172117-2 gnd Wechselwirkung (DE-588)4064937-4 gnd |
| subject_GND | (DE-588)4003115-9 (DE-588)4172117-2 (DE-588)4064937-4 (DE-588)4143413-4 |
| title | Drug nucleic acid interactions |
| title_auth | Drug nucleic acid interactions |
| title_exact_search | Drug nucleic acid interactions |
| title_full | Drug nucleic acid interactions ed. by Jonathan B. Chaires ... |
| title_fullStr | Drug nucleic acid interactions ed. by Jonathan B. Chaires ... |
| title_full_unstemmed | Drug nucleic acid interactions ed. by Jonathan B. Chaires ... |
| title_short | Drug nucleic acid interactions |
| title_sort | drug nucleic acid interactions |
| topic | Arzneimittel (DE-588)4003115-9 gnd Nucleinsäuren (DE-588)4172117-2 gnd Wechselwirkung (DE-588)4064937-4 gnd |
| topic_facet | Arzneimittel Nucleinsäuren Wechselwirkung Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009491114&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000000938 |
| work_keys_str_mv | AT chairesjonathanb drugnucleicacidinteractions |