The art of ovulation induction
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| Format: | Buch |
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| Sprache: | English |
| Veröffentlicht: |
Philadelphia [u.a.]
Saunders
2000
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| Schriftenreihe: | Infertility and reproductive medicine clinics of North America
11,3 |
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| Online-Zugang: | Inhaltsverzeichnis |
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| 245 | 1 | 0 | |a The art of ovulation induction |c Michael P. Diamond ... consulting ed. |
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Datensatz im Suchindex
| _version_ | 1819650112985497600 |
|---|---|
| adam_text | TH1 AKI niOVU] AVION INDUCTION
CONTENTS
Foreword xi
Michael P. Diamond and Alan H. DeCherney
Preface xiii
Fayek Nicholas Shamma
Ovulation Induction and Polycystic Ovary Syndrome 347
Rebecca C. Amaru and Alan B. Copperman
The management of anovulatory infertility in women with polycys¬
tic ovary syndrome (PCOS) has evolved significantly over the last
60 years. PCOS is now known to be a heterogeneous collection
of endocrine disturbances often involving hyperandrogenism and
insulin resistance. Treatments have become more sophisticated and
should target specific endocrinopathies. A comprehensive ap¬
proach toward inducing ovulation in these patients must take into
consideration the complexities of the disease and the risks and
benefits of a range of approaches. In this article, a historical perspec¬
tive of the disease is presented and a variety of methodologies
used to safely induce ovulation in patients with PCOS is discussed.
Endometriosis and Ovulation Induction 369
Jacqueline N. Gutmann
Several mechanisms exist that can reduce infertility through endo¬
metriosis, including impaired folliculogenesis. This article explores
the role of ovulation induction as a treatment of endometriosis
associated infertility. The use of adjuvant suppressive treatment
is also addressed. The success of in vitro fertilization in patients
with endometriosis is reviewed.
ENFERTUJTY AND REPRODUCTIVE MEDICINE
CLINICS OF NORTH AMERICA
VOLUME 11 NUMBER 3 JULY 2000 V
The Use of Ovulation Induction in the Treatment of
Unexplained Infertility 385
Gaurang Daftary and Hugh S. Taylor
Unexplained infertility is a diagnosis of exclusion made after elimi¬
nating known causes of infertility in a standard evaluation. Despite
the lack of identifiable causes, empiric treatment is often successful.
Ovulation induction with clomiphene citrate or gonadotrophins
should be part of the initial therapy for this condition.
Ovarian Hyperstimulation Syndrome 399
Doreen L. Hock and David B. Seifer
Ovarian hyperstimulation syndrome often results from stimulation
with gonadotropins as a treatment for infertility. Strict monitoring
of E2 levels and follicular count should be maintained in an attempt
to predict its occurrence. Preventative measures, such as with¬
holding or substituting human chorionic gonadotropin with a
gonadotrophin releasing hormone agonist, withholding further
gonadotrophin therapy, administration of albumin, and, in cases
of in vitro fertilization, aspiration of ovarian follicles and cryopres
ervation may be beneficial. Therapy is supportive in nature with
surgical intervention reserved for those cases involving intraperito
neal hemorrhage or ovarian torsion.
The Biologic Basis of Reproductive Senescence
in Women 419
David L. Keefe
Ample evidence demonstrates that fertility in women declines with
age, even after controlling for other causes of infertility. Because
women increasingly delay marriage and attempts at childbearing
within marriage, age related infertility has become a growing clini¬
cal problem. This article discusses the cellular and molecular mech¬
anisms of reproductive senescence, examining the role of mitochon¬
dria in cellular senescence through mutations in mitochondrial
DNA and the promotion of programmed cell death. The article
also discusses the roles of genomic instability, aneuploidy, and
telomeres in reproductive senescence.
New Ovulation Induction Agents 439
Alan S. Penzias
In the past, the sole source of human luteinizing hormone and
human follicle stimulating hormone for clinical use was the urine
of postmenopausal women. Recombinant DNA technology has
now enabled direct production of these gonadotropins. This article
vi CONTENTS
describes how the recombinant products are created and relates
their success in clinical practice.
Ovulation Induction and Assisted Reproduction 455
Kim L. Thornton
This article discusses many of the randomized controlled trials
comparing the new recombinant gonadotropins for ovulation in¬
duction with the urinary products. Ovulation induction regimens
for patients who have typically been classified as hyperresponders
are reviewed, and the new regimens that have been developed to
improve the response of women who are poor responders are pre¬
sented.
Multifetal Pregnancy Reduction 471
Joseph K. Hwang and Grace Lee
The escalating use of gonadotrophin ovulatory drugs and assisted
reproductive technology in the last two decades has resulted in a
dramatic upsurge of iatrogenic multifetal pregnancies and concom¬
itant complications. Multifetal pregnancy reduction (MFPR) was
introduced as a viable therapeutic option to circumvent the most
common complications associated with high order multifetal preg¬
nancies. MFPR is a reasonable and effective therapeutic option for
infertile couples faced with the enormous physical and psychologic
burden of carrying high order multifetal pregnancies.
Value of Superovulation Combined With
Intrauterine Insemination 481
Anuja Dokras and Antoni J. Duleba
Superovulation combined with intrauterine insemination (IUI) is
used for a variety of indications. For patients with unexplained
infertility, there is adequate evidence in the literature demon¬
strating an increase in pregnancy rates with the addition of IUI to
superovulation with gonadtropins. For patients with male factor
infertility, the addition of superovulation to IUI may improve preg¬
nancy rates. The cost effectiveness of these approaches needs to
be further evaluated.
The Use of Natural Progesterone in
Assisted Reproduction 495
Fayek Nicholas Shamma
In this article, the role of progesterone in modifying endometrial
receptivity is presented. The luteal phase following controlled ovar
CONTENTS vii
ian hyperstimulation (COH) is evaluated. The article also discusses
the use of progesterone for luteal support in the context of COH.
The role of natural progesterone in assisted reproduction is pre¬
sented.
Ethical Considerations of Ovulation Induction 503
Joumana B. Kayrouz
This article illustrates how assisted reproduction techniques, al¬
though helpful to thousands of infertile couples, raise moral and
legal dilemmas created by conflicting moral principles that gener¬
ate conflicting demands. The goal is to alert the physician to some
of these dilemmas in the specific context of ovulation induction
and to illustrate how medical decisions in the context of assisted
production must often be guided by ethical considerations.
Index 511
Subscription Information Inside back cover
viii CONTENTS
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| physical | XIV S., S. 347 - 514 Ill., graph. Darst. |
| publishDate | 2000 |
| publishDateSearch | 2000 |
| publishDateSort | 2000 |
| publisher | Saunders |
| record_format | marc |
| series | Infertility and reproductive medicine clinics of North America |
| series2 | Infertility and reproductive medicine clinics of North America |
| spellingShingle | The art of ovulation induction Infertility and reproductive medicine clinics of North America Ovulationsinduktion (DE-588)4251622-5 gnd |
| subject_GND | (DE-588)4251622-5 (DE-588)4143413-4 |
| title | The art of ovulation induction |
| title_auth | The art of ovulation induction |
| title_exact_search | The art of ovulation induction |
| title_full | The art of ovulation induction Michael P. Diamond ... consulting ed. |
| title_fullStr | The art of ovulation induction Michael P. Diamond ... consulting ed. |
| title_full_unstemmed | The art of ovulation induction Michael P. Diamond ... consulting ed. |
| title_short | The art of ovulation induction |
| title_sort | the art of ovulation induction |
| topic | Ovulationsinduktion (DE-588)4251622-5 gnd |
| topic_facet | Ovulationsinduktion Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009066036&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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