The IGF system molecular biology, physiology, and clinical applications

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Veröffentlicht: Totowa, NJ Humana Pr. 1999
Schriftenreihe:Contemporary endocrinology 17
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Datensatz im Suchindex

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adam_text CONTENTS Preface v Contributors ix 1 Historical Perspective: The Origins and Development of the Somatomedin Hypothesis 1 William H. Daughaday and William D. Salmon, Jr. I MOLECULAR BIOLOGY OF THE IGF SYSTEM 2 Molecular Biology of IGF I and IGF II 19 Peter Rotwein 3 Regulation of IGF Gene Expression 37 P. Elly Holthuizen, Paul H. Steenbergh, and John S. Sussenbach 4 Molecular Biology of the Type 1 IGF Receptor 63 Haim Werner 5 Molecular Biology of the IGF II/Mannose 6 Phosphate Receptor 89 Wieland Kiess 6 Molecular Biology of the IGF Binding Proteins Ill Guck T. Ooi and Yves R. Boisclair II BIOLOGICAL ACTIONS OF THE IGFs 7 IGF I Receptor Function: Transducing the IGF I Signal into Intracellular Events 143 Vicky A. Blakesley, Andrew A. Butler, Anatolii P. Koval, Yumiko Okubo, and Derek LeRoith 8 Type 2 IGF Receptor Mediated Events 165 S. Peter Nissley 9 Alternative IGF Related Receptors 199 Kenneth Siddle and Maria A. Soos 10 IGF Binding Proteins as Modulators of IGF Action 227 Janet L. Martin and Robert C. Baxter 11 IGF Independent Actions of the IGF Binding Proteins 257 Youngman Oh and Ron G. Rosenfeld 12 IGF Binding Proteins and Extracellular Matrix 273 David R. Clemmons 13 Biological Actions of Proteolytic Fragments of the IGF Binding Proteins 281 Michel Binoux, Claude Lalou, and Sarah Mohseni Zadeh 14 The IGF Binding Protein Superfamily 315 Vivian Hwa, Youngman Oh, Christine P. Burren, Won Kyu Choi, Donna L. Graham, Angela Ingermann, Ho Seong Kim, Abel Lopez Bermejo, Giuseppe Minniti, Srinivasa R. Nagalla, Kisoo Pai, Anna Spagnoli, Peter Vorwerk, Don L. V. Wanek, Elizabeth M. Wilson, Yoshitaka Yamanaka, Doo Hyun Yang, and Ron G. Rosenfeld vii viii Contents 15 IGFs and Cell Growth 329 Renato Baserga, Marco Prisco, and Atsushi Hongo 16 Posttranslational Modification of the IGF Binding Proteins 355 Cheryl A. Conover III IGF PHYSIOLOGY 17 IGFs in the Female Reproductive System 379 Linda C. Giudice 18 The IGF Axis in the Male Reproductive System 407 Stuart A. Weinzimer and Pinchas Cohen 19 IGFs and the Nervous System 425 Phillip S. Leventhal, James W. Russell, and Eva L. Feldman 20 IGF System Components and Their Role in Bone Metabolism 457 Subburaman Mohan and David J. Baylink 21 IGFs and Skeletal Muscle 497 Stephen M. Rosenthal 22 IGFs and the Digestive Tract 517 P. Kay Lund 23 Actions of IGF System Proteins from Studies of Transgenic and Gene Knockout Models 545 A. Joseph D Ercole IV CLINICAL ASPECTS OF THE IGFs 24 Metabolic Effects of IGFs 577 Jtirgen Zapf, E. Rudolph Froesch, and Christoph Schmid 25 Clinical Uses of IGF I and IGF Binding Protein Assays 617 Louis E. Underwood 26 IGF Binding Protein Proteolysis in Various Clinical States 633 Laura A. Maile, Anna L. Crown, and Jeff M.P. Holly 27 IGF Deficiency 651 Katie A. Woods and Martin O. Savage 28 Tumor Hypoglycemia Linked to IGF II 675 Christian A. Koch, Kristina I. Rother, and Jesse Roth 29 IGFs in the Evaluation of Acromegaly 699 Marlys R. Drange and Shlomo Melmed 30 IGF in the Treatment of Diabetes 721 Robert A. Gabbay and Alan C. Moses 31 IGF I Treatment of Growth Hormone Insensitivity 739 Arlan L. Rosenbloom Index 771
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publishDate 1999
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series Contemporary endocrinology
series2 Contemporary endocrinology
spelling The IGF system molecular biology, physiology, and clinical applications ed. by Ron G. Rosenfeld ...
Totowa, NJ Humana Pr. 1999
XII, 787 S. Ill., graph. Darst.
txt rdacontent
n rdamedia
nc rdacarrier
Contemporary endocrinology 17
Biologia molecular larpcal
Endocrinologia larpcal
Proteína 1 de ligação aos fatores de crescimento insulin-like larpcal
Proteínas larpcal
Reguladores de crescimento larpcal
Somatomedinas larpcal
Insulin-Like Growth Factor I physiology
Insulin-Like Growth Factor I therapeutic use
Insulin-Like Growth Factor II physiology
Insulin-Like Growth Factor II therapeutic use
Insulin-Like Growth-Factor-Binding Proteins physiology
Insulin-like grow factor-binding proteins
Molecular Biology
Somatomedin Pathophysiology
Somatomedin Physiological effect
Rosenfeld, Ron G. Sonstige oth
Contemporary endocrinology 17 (DE-604)BV010861132 17
HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008735674&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
spellingShingle The IGF system molecular biology, physiology, and clinical applications
Contemporary endocrinology
Biologia molecular larpcal
Endocrinologia larpcal
Proteína 1 de ligação aos fatores de crescimento insulin-like larpcal
Proteínas larpcal
Reguladores de crescimento larpcal
Somatomedinas larpcal
Insulin-Like Growth Factor I physiology
Insulin-Like Growth Factor I therapeutic use
Insulin-Like Growth Factor II physiology
Insulin-Like Growth Factor II therapeutic use
Insulin-Like Growth-Factor-Binding Proteins physiology
Insulin-like grow factor-binding proteins
Molecular Biology
Somatomedin Pathophysiology
Somatomedin Physiological effect
title The IGF system molecular biology, physiology, and clinical applications
title_auth The IGF system molecular biology, physiology, and clinical applications
title_exact_search The IGF system molecular biology, physiology, and clinical applications
title_full The IGF system molecular biology, physiology, and clinical applications ed. by Ron G. Rosenfeld ...
title_fullStr The IGF system molecular biology, physiology, and clinical applications ed. by Ron G. Rosenfeld ...
title_full_unstemmed The IGF system molecular biology, physiology, and clinical applications ed. by Ron G. Rosenfeld ...
title_short The IGF system
title_sort the igf system molecular biology physiology and clinical applications
title_sub molecular biology, physiology, and clinical applications
topic Biologia molecular larpcal
Endocrinologia larpcal
Proteína 1 de ligação aos fatores de crescimento insulin-like larpcal
Proteínas larpcal
Reguladores de crescimento larpcal
Somatomedinas larpcal
Insulin-Like Growth Factor I physiology
Insulin-Like Growth Factor I therapeutic use
Insulin-Like Growth Factor II physiology
Insulin-Like Growth Factor II therapeutic use
Insulin-Like Growth-Factor-Binding Proteins physiology
Insulin-like grow factor-binding proteins
Molecular Biology
Somatomedin Pathophysiology
Somatomedin Physiological effect
topic_facet Biologia molecular
Endocrinologia
Proteína 1 de ligação aos fatores de crescimento insulin-like
Proteínas
Reguladores de crescimento
Somatomedinas
Insulin-Like Growth Factor I physiology
Insulin-Like Growth Factor I therapeutic use
Insulin-Like Growth Factor II physiology
Insulin-Like Growth Factor II therapeutic use
Insulin-Like Growth-Factor-Binding Proteins physiology
Insulin-like grow factor-binding proteins
Molecular Biology
Somatomedin Pathophysiology
Somatomedin Physiological effect
url http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008735674&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
volume_link (DE-604)BV010861132
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