Stochastic decision predicates a scheme to represent motifs

Abstract: "This paper presents a new scheme for classifying genetic sequences, called Stochastic Decision Predicates. A stochastic decision predicate consists of Horn clauses and their probability parameters, and represents a (stochastic) motif that denotes a probabilistic mapping from a geneti...

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Bibliographische Detailangaben
Hauptverfasser: Konagaya, Akihiko (VerfasserIn), Yamanishi, Kenji (VerfasserIn)
Format: Buch
Sprache:English
Veröffentlicht: Tokyo, Japan 1991
Schriftenreihe:Shin-Sedai-Konpyūta-Gijutsu-Kaihatsu-Kikō <Tōkyō>: ICOT technical report 657
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Zusammenfassung:Abstract: "This paper presents a new scheme for classifying genetic sequences, called Stochastic Decision Predicates. A stochastic decision predicate consists of Horn clauses and their probability parameters, and represents a (stochastic) motif that denotes a probabilistic mapping from a genetic sequence to a set of categories, such as protein families. For the selection of stochastic decision predicates, quantative evaluation is possible from the viewpoint of predictive performance for unknown sequences as well as discrimination performance for the given genetic sequences. We employ Rissanen's Minimum Description Length (MDL) principle in order to avoid overlearning caused by the statistical fluctuation
Our experimental results demonstrate that the MDL principle produces motifs with less predictive errors than the maximum likelihood method.
Beschreibung:7 S.