Controversies in critical care medicine

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Sprache:English
Veröffentlicht: Philadelphia [u.a.] Saunders 1996
Schriftenreihe:Critical care clinics 12,3
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Datensatz im Suchindex

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adam_text ! CONTROVERSIES IN CRITICAL CARE MEDICINE CONTENTS Preface xiii Andrew B. Leibowitz ICU Scoring Systems Allow Prediction of Patient Outcomes and Comparison of ICU Performance 503 Richard B. Becker and Jack E. Zimmerman Data support the use of prognostic systems for evaluating ICU performance. ICU effectiveness can be assessed by comparing actual and predicted group death rates, and efficiency can be assessed by comparing ICU length of stay and resource use. Prognostic estimates that consider daily changes in physiology provide an objective measure of an individual patient s response to therapy. These prognostic estimates can be used to support clinical decisions, but must be used as a supplement rather than as a substitute for good clinical judgment. ICU Scoring Systems Do Not Allow Prediction of Patient Outcomes or Comparison of ICU Performance 515 John P. Sherck and Clayton H. Shatney Recent revisions of the major ICU scoring systems have broad¬ ened their database markedly and increased their statistical accu¬ racy. For a specific patient, however, the systems cannot be accu¬ rate enough to direct management decisions. Significant questions remain about the reliability of these systems for comparing differ¬ ent ICUs and different patient populations, especially in surgical and trauma patients. Current scoring systems, therefore, cannot be used reliably in either the management of the individual patient or in the making of quality comparisons between ICUs. CRITICAL CARE CLINICS VOLUME 12 • NUMBER 3 • JULY 1996 vii Does a Full Time, 24 Hour Intensivist Improve Care and Efficiency? 525 Richard W. Carlson, Dennis E. Weiland, and Komandoor Srivathsan This article reviews the hypothesis that staffing with full time intensive care physicians leads to improvements in the manage¬ ment of ICUs and in the outcome for ICU patients. Variations in the professional organization of critical care units in the United States are discussed. The advantages and disadvantages of open, closed, and transitional (comanagement) ICU organizational structures are presented. Does Pulmonary Artery Catheter Use Change Outcome? Yes 553 Louis R. M. Del Guercio This article discusses the advantages of pulmonary artery cathe¬ ters, with emphasis on the Swan Ganz catheter. Various studies and published reports confirming the efficacy of pulmonary ar¬ tery catheter use are reviewed. In the author s opinion, it is evident that the Swan Ganz catheter has withstood the test of time and scrutiny. Do Pulmonary Artery Catheters Improve Patient Outcome? No 559 Andrew B. Leibowitz Although pulmonary artery catheters provide physiologic infor¬ mation previously unobtainable by other means, their effect on patient outcome remains questionable. Risks associated with their use, the inherent inaccuracy of the data collected, problems with general interpretation of data, and the potential for ineffective, inappropriate, and injurious interventions based on data pro¬ vided by pulmonary artery catheterization make it an unproven therapy when applied to large patient groups. The notion that pulmonary artery catheterization does not improve patient out¬ come has recently been supported by literature reviews, clinical investigations, and surveys of patient outcome. Does Gastric Tonometry Work? Yes 569 Steven D. Brown and Guillermo Gutierrez Gastric tonometry is gaining acceptance rapidly as a noninvasive method of monitoring tissue dysoxia in a key organ system that previously could not he assessed easily. In addition to being noninvasive, gastric tonometry also identifies dysoxia in shock sooner than currently available monitors. This allows for more timely intervention with a subsequent improvement in prognosis in defined groups of patients. Tonometry data that suggest con¬ tinued dysoxia despite intervention should signal clinicians to seek alternative diagnoses or to question the efficacy of current therapies, including antibiotics. viii CONTENTS Does Gastric Tonometry Work? No 587 Ernest Benjamin and John M. Oropello Gastrointestinal tonometry is supposed to diagnose gut mucosal hypoxia using gastric luminal Pco2 and arterial bicarbonatemia, which are substituted in a modified Henderson Hasselbach equa¬ tion. This article reviews some of the problems inherent to the multiple assumptions underlying this technique. Tonometry is influenced by several local factors and by systemic acid base imbalances that are unrelated to oxygenation. Tonometry is a rather crude and cumbersome method of gut capnometry, a tech¬ nology that may provide valuable information regarding visceral perfusion, but not necessarily oxygenation. High Inflation Pressure and Positive End expiratory Pressure: Injurious to the Lung? No 603 Loren D. Nelson Recent published reports have arrived at conflicting conclusions regarding the potential adverse effects of high inflation pressure on ventilator induced lung injury. The contribution of positive end expiratory pressure to high airway pressure induced lung injury is even more controversial. Oxygen toxicity, macrobaro trauma, and volutrauma interact to produce ventilator induced lung injury. This article explores the many manifestations of ventilator induced lung injury and the means proposed to pre¬ vent or limit its physiologic effects. High Inflation Pressure and Positive End expiratory Pressure: Injurious to the Lung? Yes 627 Peter J. Papadakos and Michael J. Apostolakos The traditional practice of using high inflation pressure and high levels of positive end expiratory pressure has fallen out of favor. New modes of mechanical ventilation have been developed that emphasize lung protection and are based on physiologic parame¬ ters. Pressure control and pressure regulated volume control are two such modes that may be used in a lung protective strategy. The early use of this technique may limit barotrauma and allow for rapid weaning. Does Increasing Oxygen Delivery Improve Outcome? Yes 635 Kathleen M. Kelly Clinical outcomes continue to support the necessity of main¬ taining an optimal level of oxygen delivery in critically ill pa¬ tients, yet the question remains as to what optimal oxygen deliv¬ ery is. This article discusses several concepts related to the issue of oxygen delivery, including flow dependency and mathematical coupling, oxygen debt and its correlation with mortality, and lactate levels as they relate to the prediction of survival. CONTENTS ix Does Increasing Oxygen Delivery Improve Outcome in the Critically 111? No 645 Juan J. Ronco, John C. Fenwick, and Martin G. Tweeddale The strategy of treating critically ill patients by increasing oxygen delivery and consumption to values previously observed among survivors of critical illness (supranormal values) is based on the belief that (1) tissue hypoxia may persist in critically ill patients despite aggressive early resuscitation to traditional endpoints of adequate tissue perfusion and (2) that increasing oxygen delivery can reverse tissue hypoxia. This article addresses the question of whether increasing oxygen delivery improves outcomes in criti¬ cally ill patients by reviewing the relationship between whole body oxygen delivery and consumption and by critically examin¬ ing the randomized controlled trials that have increased oxygen delivery to supranormal values. Early Nutritional Support in Critical Illness Is Important 661 Harry C. Sax The hypermetabolic state in critically ill patients is characterized by wasting of lean body mass and immunosuppression. The gut is among the most metabolically active organs. Failure to main¬ tain gut function by way of early enteral nutrition can lead to increased infectious complications. Early enteral nutrition im¬ proves outcome and may maintain muscle mass by blunting the cytokine mediated hypermetabolic response. Nutrition Support Is Not Beneficial and Can Be Harmful in Critically 111 Patients 667 Paul L. Marino and Matthew J. Finnegan Malnutrition in critical illness is the result of abnormal metabo¬ lism in the host, and it is unlike the malnutrition of starvation, in which the cause is inadequate nutrient intake. To correct the nutrient defects in critically ill patients, resolution of metabolic abnormalities, not the intake of nutrient substrates, is needed. This article demonstrates that there is little evidence to indicate that nutrition support is beneficial as therapy for seriously ill pa¬ tients. Is Renal Dose Dopamine Protective or Therapeutic? Yes 677 Olivia V. Carcoana and Roberta L. P Tines The ability of renal dose dopamine to augment renal function in a variety of clinical settings has been documented. The direct action of dopamine or dopamine receptors contributes to the natriuretic effect of dopamine. Various clinical studies demon¬ strate the beneficial effects of renal dose dopamine in improving renal function. Although the precise mechanism responsible for this effect remains a matter of controversy, evidence supports the positive effects of renal dose dopamine. X CONTENTS Is Renal Dose Dopamine Protective or Therapeutic? No 687 David B. F. Cottee and W. Peter Saul This article argues that dopamine infused in low doses has not been shown to avert the onset of or ameliorate the course of acute renal failure in critically ill patients. The inotropic and diuretic effects of dopamine are discussed, and its adverse effects are described. An attempt is made to offer an evidence based role for low dose dopamine, namely as a diuretic in ventilated, euvolemic patients resistant to conventional diuretic therapy. Hypertensive, Hypervolemic, Hemodilutional Therapy for Aneurysmal Subarachnoid Hemorrhage: Is It Efficacious? Yes 697 Jamie S. Ullman and Joshua B. Bederson Vasospasm is an important contributor to death and disability after aneurysmal subarachnoid hemorrhage (SAH), with delayed ischemic deficits (DID) occurring in as much as 30% of patients with angiographic spasm. There is strong evidence that hyperten¬ sive, hypervolemic, hemodilutional (HHH) therapy reverses the signs of DID and that its prophylactic use reduces the incidence of DID and subsequent infarction. Improvement of outcome in even the poorest grade patients has been demonstrated. Litera¬ ture supporting the use of HHH therapy in aneurysmal SAH is reviewed. Hypertensive, Hypervolemic, Hemodilutional Therapy for Aneurysmal Subarachnoid Hemorrhage: Is It Efficacious? No 709 John M. Oropello, Larry Weiner, and Ernest Benjamin Many neurosurgeons routinely use hypertensive, hypervolemic, hemodilutional, or hyperdynamic therapy (HT) in some form to prevent or to treat vasospasm. Despite the widespread use of this therapy during the past 20 years, however, there are no randomized, prospective, controlled clinical studies demonstra¬ ting that HT improves the short or long term neurologic outcome or survival after subarachnoid hemorrhage. Guidelines need to be developed to standardize the clinical application of HT, and well controlled, prospective, randomized clinical trials must be conducted before HT can become an accepted treatment for vaso¬ spasm. Special Article The Aorta: Aortic Aneurysm, Trauma, and Dissection 733 Raimund Erbel and Jose Zamorano Because of the close relationship between the esophagus and the aorta, multiplane transesophageal echocardiography provides an excellent way to view the thoracic aorta. In this article, clinical CONTENTS Xi features of aortic aneurysm, trauma, and aortic dissection are described, as is the potential use of transesophageal echocardiog raphy in the assessment of these entities. Index 767 Subscription Information Inside back cover xii CONTENTS
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spelling Controversies in critical care medicine Andrew B. Leibowitz, guest ed.
Philadelphia [u.a.] Saunders 1996
XII S., S. 503 - 700 Ill., graph. Darst.
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spellingShingle Controversies in critical care medicine
Critical care clinics
Therapieerfolg (DE-588)4126073-9 gnd
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title Controversies in critical care medicine
title_auth Controversies in critical care medicine
title_exact_search Controversies in critical care medicine
title_full Controversies in critical care medicine Andrew B. Leibowitz, guest ed.
title_fullStr Controversies in critical care medicine Andrew B. Leibowitz, guest ed.
title_full_unstemmed Controversies in critical care medicine Andrew B. Leibowitz, guest ed.
title_short Controversies in critical care medicine
title_sort controversies in critical care medicine
topic Therapieerfolg (DE-588)4126073-9 gnd
Intensivtherapie (DE-588)4027258-8 gnd
Intensivmedizin (DE-588)4027263-1 gnd
topic_facet Therapieerfolg
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