Novel functions of cholinesterases in development, physiology and disease with 6 tables
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| Hauptverfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Stuttgart ; New York
Fischer
1995
|
| Schriftenreihe: | Progress in histochemistry and cytochemistry
29,3 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
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| 100 | 1 | |a Layer, Paul G. |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Novel functions of cholinesterases in development, physiology and disease |b with 6 tables |c Paul G. Layer ; Elmar Willbold |
| 264 | 1 | |a Stuttgart ; New York |b Fischer |c 1995 | |
| 300 | |a VI, 94 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Progress in histochemistry and cytochemistry |v 29,3 | |
| 650 | 7 | |a Cholinesterases |2 gtt | |
| 650 | 4 | |a Cholinesterases | |
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| 650 | 0 | 7 | |a Zentralnervensystem |0 (DE-588)4067637-7 |2 gnd |9 rswk-swf |
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| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-006716357 | |
Datensatz im Suchindex
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| _version_ | 1822685267734036481 |
| adam_text | Contents
1 Introduction: New perspectives of a classic molecule 1
1.1 Occurrence of molecular forms of cholinesterases 3
1.2 Genes and biosynthesis of cholinesterases 4
1.3 Membrane association of embryonic brain cholinesterases 5
1.4 Molecular diversities for novel functions ? 6
1.4.1 Different active and peripheral sites on cholinesterases 6
1.4.2 Glyco epitopes for novel functions? 7
1.4.3 Inactive cholinesterases with functional glycoepitopes? 7
1.5 Cholinesterases belong to a new family of proteins 9
2 Novel functions in development 9
2.1 Small molecular forms for embryonic functions? 9
2.2 Expression patterns indicate a role for cholinesterases during develop¬
ment 10
2.2.1 Cholinesterases in photoreceptors of Drqsophila 11
2.2.2 Cholinesterases and mammalian neurogenesis 11
2.3 Cholinesterases and cell proliferation ..... 17
2.3.1 Butyrylcholinesterase in stem cells of the chicken eye margin 20
2.3.2 Butyrylcholinesterase stimulates cell proliferation 21
2.4 Butyrylcholinesterase in Schwann cells 21
2.5 Cholinesterases and cell migration 25
2.5.1 Cholinesterases as cell adhesion molecules 29
2.5.2 Cholinesterases and axonal growth 30
2.6 Novel functions tested in vitro 34
2.6.1 Neurite growth is altered by anticholinesterases 36
2.6.2 Butyrylcholinesterase activity regulates acetylcholinesterase expression . 40
2 7 An autoimmunity model for neurogenetic cholinesterase functions .... 40
3 Novel functions in physiology 43
3 1 Secreted acetylcholinesterase as neuromodulator in the substantia
nigra? 43
3.2 Acetylcholinesterase release in the cerebellum 45
3.3 Butyrylcholinesterase and the blood brain barrier 46
3.4 YT blood group antigen is on erythrocyte s acetylcholinesterase 46
3 5 A role for tetrameric butyrylcholinesterase in the retina? 47
3.6 Enzymatic side activities on cholinesterases 47
3.6.1 Peptidase and protease activities on cholinesterases? 48
3.6.2 An amine sensitive arylacylamidase activity of acetylcholinesterase and
butyrylcholinesterase 50
3.7 Lipoproteins and serum cholinesterase 51
4 Novel functions in pathology 53
VI • Contents
4.1 Pathology and embryology 53
4.2 Neural tube defects 54
4.3 Alzheimer s disease 55
4.3.1 First period: Acetylcholmesterase and the «chohnergic hypothesis* ... 55
4.3.2 Second «(3 amyloid/tau period» 56
4.3.3 Third «synthetic» period: Non classical functions for cholinesterases in
Alzheimer s disease? 57
4.4 Cholinesterases and carcinomas 60
4.5 Cholinesterases in syndromes of hemopoietic cell division 61
5 Concluding remarks 63
Tables 64
References 69
Subject index 93
|
| any_adam_object | 1 |
| author | Layer, Paul G. Willbold, Elmar |
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| ctrlnum | (OCoLC)33095297 (DE-599)BVBBV010114552 |
| dewey-full | 574.805 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 574 - [Unassigned] |
| dewey-raw | 574.805 |
| dewey-search | 574.805 |
| dewey-sort | 3574.805 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| format | Book |
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| id | DE-604.BV010114552 |
| illustrated | Illustrated |
| indexdate | 2024-12-23T13:51:42Z |
| institution | BVB |
| isbn | 3437116282 1560814152 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-006716357 |
| oclc_num | 33095297 |
| open_access_boolean | |
| owner | DE-19 DE-BY-UBM DE-12 DE-355 DE-BY-UBR |
| owner_facet | DE-19 DE-BY-UBM DE-12 DE-355 DE-BY-UBR |
| physical | VI, 94 S. Ill., graph. Darst. |
| publishDate | 1995 |
| publishDateSearch | 1995 |
| publishDateSort | 1995 |
| publisher | Fischer |
| record_format | marc |
| series | Progress in histochemistry and cytochemistry |
| series2 | Progress in histochemistry and cytochemistry |
| spellingShingle | Layer, Paul G. Willbold, Elmar Novel functions of cholinesterases in development, physiology and disease with 6 tables Progress in histochemistry and cytochemistry Cholinesterases gtt Cholinesterases Krankheit (DE-588)4032844-2 gnd Neurophysiologie (DE-588)4041897-2 gnd Zentralnervensystem (DE-588)4067637-7 gnd Cholinesterase (DE-588)4122098-5 gnd |
| subject_GND | (DE-588)4032844-2 (DE-588)4041897-2 (DE-588)4067637-7 (DE-588)4122098-5 |
| title | Novel functions of cholinesterases in development, physiology and disease with 6 tables |
| title_auth | Novel functions of cholinesterases in development, physiology and disease with 6 tables |
| title_exact_search | Novel functions of cholinesterases in development, physiology and disease with 6 tables |
| title_full | Novel functions of cholinesterases in development, physiology and disease with 6 tables Paul G. Layer ; Elmar Willbold |
| title_fullStr | Novel functions of cholinesterases in development, physiology and disease with 6 tables Paul G. Layer ; Elmar Willbold |
| title_full_unstemmed | Novel functions of cholinesterases in development, physiology and disease with 6 tables Paul G. Layer ; Elmar Willbold |
| title_short | Novel functions of cholinesterases in development, physiology and disease |
| title_sort | novel functions of cholinesterases in development physiology and disease with 6 tables |
| title_sub | with 6 tables |
| topic | Cholinesterases gtt Cholinesterases Krankheit (DE-588)4032844-2 gnd Neurophysiologie (DE-588)4041897-2 gnd Zentralnervensystem (DE-588)4067637-7 gnd Cholinesterase (DE-588)4122098-5 gnd |
| topic_facet | Cholinesterases Krankheit Neurophysiologie Zentralnervensystem Cholinesterase |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=006716357&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000005277 |
| work_keys_str_mv | AT layerpaulg novelfunctionsofcholinesterasesindevelopmentphysiologyanddiseasewith6tables AT willboldelmar novelfunctionsofcholinesterasesindevelopmentphysiologyanddiseasewith6tables |