Trends in medicinal chemistry '90 proceedings of the XIth International Symposium on Medicinal Chemistry, held in Jerusalem, Israel, 2 - 7 September 1990
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| Sprache: | English |
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Blackwell
1992
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| adam_text | INTERNATIONAL UNION OF PURE AND APPLIED CHEMISTRY TRENDS IN MEDICINAL
CHEMISTRY 90 PROCEEDINGS OF THE XLTH INTERNATIONAL SYMPOSIUM ON
MEDICINAL CHEMISTRY, HELD IN JERUSALEM, ISRAEL, 2-7 SEPTEMBER 1990
EDITED BY SHALOM SAREL DEPARTMENT OF PHARMACEUTICAL CHEMISTRY HEBREW
UNIVERSITY SCHOOL OF PHARMACY JERUSALEM, ISRAEL RAPHAEL MECHOULAM
DEPARTMENT OF NATURAL PRODUCTS HEBREW UNIVERSITY SCHOOL OF PHARMACY
JERUSALEM, ISRAEL ISRAEL AGRANAT DEPARTMENT OF ORGANIC CHEMISTRY THE
HEBREW UNIVERSITY OF JERUSALEM JERUSALEM, ISRAEL OXFORD BLACKWELL
SCIENTIFIC PUBLICATIONS LONDON EDINBURGH BOSTON MELBOURNE PARIS BERLIN
VIENNA CONTENTS PREFACE,X PLENARY LECTURES DESIGNING DRUGS FOR HISTAMINE
RECEPTORS, 1 C. R. GANELLIN, T. H. BROWN, D. G. COOPER, G. J. DURANT, R.
J. IFE, R. C. MITCHELL, G. S. SACH & R. C. YOUNG CHEMICAL CONVERSION OF
VITAMIN D3 TO ITS 1,25-DIHYDROXY METABOLITE, 11 J. KIEGIEL, P. M.
WOVKULICH & M. R. USKOKOVIC NMDA RECEPTORS: AGONISTS AND COMPETITIVE
ANTAGONISTS, 17 J. C. WATKINS PROTEIN TYROSINE KINASE BLOCKERS
(TYRPHOSTINS) AS NOVEL ANTIPROLIFERATIVE DRUGS, 31 A. LEVITZKI NEW
METHODS OF DRUG TARGETING, 35 N. BODOR RECENT ADVANCES IN THE FIELD OF
MYCOTOXINS, 45 ^ C. TAMM MAIN LECTURES RATIONAL DRUG DESIGN
COMPUTER-ASSISTED STRATEGIES STRATEGIES IN COMPUTER-ASSISTED DRUG
DESIGN, 51 N. C. COHEN SEMIEMPIRICAL QUANTUM-MECHANICAL APPROACH
MODELING OF INHIBITORS FOR HIV-1 PROTEINASE, 65 A. RAYAN, A. FLIESS, M.
KOTLER, M. CHOREV & A. GOLDBLUM CHEMICAL STRATEGIES THE PREDICTION OF
DRUG-MACROMOLECULE INTERACTIONS, 75 J. L. MARTIN, K. VELURAJA, L. N.
JOHNSON, G. W. J. FLEET, N. RAMSDEN, I. BRUCE, N. OIKONOMAKOS, A.
PAPAGEORGIOU & D. D. LEONIDAS REACTION-PATH KNOWLEDGE AS A BASIS FOR
DESIGN AND SYNTHESIS OF NOVEL PROTEASE INHIBITORS, 79 H. DUTLER, S. A.
BIZZOZERO, P. ZBINDEN & B. A. PABSCH CONTENTS PEPTIDE SURROGATES *
CHEMISTS TOOLS FOR RECEPTOR MAPPING; THE DESIGN AND ENANTIOSELECTIVE
SYNTHESIS OF PHE-ILLE SURROGATES, 87 S. SHATZMILLER, B. Z. DOLITHZKY, A.
ABIRI & P. N. CONFALONE DRUGS AFFECTING THE CNS AGONIST/ANTAGONIST
RESPONSES TO RECEPTORS OF SEROTONIN, DOPAMINE AND TO THE MUSCARINE SITE
OF ACETYLCHOLINE NOVEL APPROACHES TO DRUGS ACTING ON 5-HTJ-LIKE
RECEPTORS, 97 M. P. SEILER, J. R. FOZARD, P. FLOERSHEIM, A. HAGENBACH,
D. HOYER, H. KALKMAN, A. K. MIR, P. SCHOEFFTER, H. SIEGL & A. STOLL
IMIDAZOLYLMETHYL TETRAHYDROCARBAZOLONES AND INDOLYL PROPANONES AS 5-HT 3
ANTAGONISTS, 107 R. BARRETT, D. CAVALLA, I. H. COATES, C. ELDRED, G. B.
EWAN, N. GODFREY, D. C. HUMBER, P. C. NORTH & A. W. OXFORD 8-OH
DPAT-DERIVED 5-HT 1A -RECEPTOR AGONISTS AND ANTAGONISTS, 113 U.
HACKSELL, C. MELL1N, S. E. HILLVER, L. BJORK, L. J. CORNFIELD, D. L.
NELSON & T. LEWANDER A NOVEL SERIES OF POTENTIAL ANTIDEPRESSANTS AND
SELECTIVE 5-HT UPTAKE INHIBITORS, 121 M. PROTIVA, J. JILEK, K. SINDELAR,
M. VALCHAR & J. METYSOVA SUBSTITUTED SALICYLAMIDES AND BENZAMIDES; A
VERSATILE POOL OF DOPAMINE D 2 RECEPTOR ANTAGONISTS, 127 T. HOGBERG
NOVEL AMINOPYRIDAZINE-DERIVED SELECTIVE MUSCARINIC AGONISTS AS POTENTIAL
DRUGS FOR SENILE DEMENTIA, 135 C. G. WERMUTH, J. J. BOURGUIGNON & R.
HOFFMANN AGONIST/ANTAGONIST RESPONSES TO RECEPTORS OF EXCITATORY AMINO
ACIDS THE DEVELOPMENT OF NMDA RECEPTOR ANTAGONISTS AS USEFUL THERAPEUTIC
AGENTS, 145 D. M. ZIMMERMAN, P. L. ORNSTEIN, D. D. SCHOEPP & J. D.
LEANDER DESIGN, SYNTHESIS AND MOLECULAR MODELING OF
PHOSPHONOALKYL-SUBSTITUTED TETRAHYDROISOQUINOLINES AS COMPETITIVE NMDA
ANTAGONISTS, 153 C. F. BIGGE, C. HUMBLET, G. JOHNSON, T. MALONE, D. F.
ORTWINE & G. W. PINTER EXCITATORY AMINO ACID ANTAGONISTS, 161 T. HONORE,
L. N^ERUM, F. E. NIELSEN & P. JACOBSEN NON-COMPETITIVE
A/-METHYL-D-ASPARTATE ANTAGONISTS; STRUCTURE-ACTIVITY RELATIONSHIPS FOR
COMPOUNDS ACTING AT THE ION CHANNEL AND GLYCINE SITES, 169 P. D. LEESON,
R. W. CARLING, B. J. WILLIAMS, R. BAKER, T. LADDUWAHETTY, K. W. MOORE,
M. ROWLEY, A. C. FOSTER, J. A. KEMP & M. D. TRICKLEBANK DESIGN,
SYNTHESIS AND EXCITATORY ACTIVITY OF CONFORMATIONALLY RESTRICTED
L-GLUTAMATE ANALOGUES IN THE MAMMALIAN CENTRAL NERVOUS SYSTEM, 175 Y.
OHFUNE & K. SHIMAMOTO CONTENTS SYNTHESIS AND SOME PHARMACOLOGICAL
PROPERTIES OF ODAP ANALOGUES, 183 L. B. PIOTROVSKY, M. A. DUMP1S, A. P.
GARYAEV & Y. V. ZAITZEV DRUGS AFFECTING THE ADENYLATE CYCLASE AND THE
INOSITOL TRIPHOSPHATE- DIACYLGLYCEROL SYSTEMS CANNABINOID RECEPTOR
LIGANDS, 193 A. C. HOWLETT INHIBITOR DESIGN FOR INOSITOL
MONOPHOSPHATASE, 199 R. BAKER, J. J. KULAGOWSKI, P. D. LEESON & N. J.
LIVERTON AGONIST/ANTAGONIST RESPONSES TO EICOSANOID RECEPTORS
LEUKOTRIENE METABOLISM, 209 J. ROKACH & E. G. SPOKAS THROMBOXANE
BIOSYNTHESIS AND INHIBITION IN MAN, 215 P. PATRIGNANI & C. PATRONO THE
SEARCH FOR PEPTIDOLEUKOTRIENE ANTAGONISTS, 219 A. VON SPRECHER, A.
SALLMANN, A. BECK, W. BREITENSTEIN, H. WIESTNER, S. KIMMEL, W. H.
ANDERSON, G. P. ANDERSON, N. SUBRAMANIAN & M. A. BRAY DRUGS ASSOCIATED
WITH BRADYKININ AND PLATELET ACTIVATING FACTOR NOVEL HIGHLY POTENT
BRADYKININ ANTAGONISTS AND THEIR IMPACT ON ALLERGIC DISEASES, 229 S.
HENKE, A. ANAGNOSTOPOULOS, G. BREIPOHL, H. GERHARDS, J. KNOLLE, B.
SCHOLKENS & F. LEMBECK PAF ANTAGONISTS IN THE HETRAZEPINOIC SERIES,
233 K. H. WEBER, F. BIRKE & H. KOPPEN DRUGS TARGETED AT THE
CARDIOVASCULAR SYSTEM CHEMICAL APPROACHES TO THE TREATMENT OF
ATHEROSCLEROSIS, 243 D. T. WITIAK, D. R. FELLER & H. A. I. NEWMAN
SPECIFIC BRADYCARDIC AGENTS * A NOVEL APPROACH TO THE TREATMENT OF
MYOCARDIAL ISCHEMIA, 257 B. WETZEL PROGRESS IN THE SYNTHESIS AND DESIGN
OF RENIN INHIBITORS, 265 Q. BRANCA, J. P. CLOZEL, W. FISCHLI, W.
NEIDHART, H. STADLER & W. WOSTL STRUCTURE ACTIVITY STUDIES AND RECEPTOR
BINDING MODEL OF L-BENZAZEPIN-2-ONE CALCIUM ANTAGONISTS, 271 S. D.
KIMBALL, D. M. FLOYD, J. C. BARRISH, J. DAS, J. T. HUNT, J. KRAPCHO, G.
ROVNYAK, K. J. DUFF, M. LAGO, V. G. LEE, R. V. MOQUIN, S. SPERGEL, J. Z.
GOUGOUTAS, M. MALLEY, A. PUDZIANOWSKI, S. F. FLAIM, S. MORELAND, A.
HEDBERG & R. E. WHITE CONTENTS SYNTHESIS OF CARDIOACTIVE STEROIDS, 277
P. WELZEL, B. JANSSEN, H. STEIN, T. MILKOWA, H. W. HOPPE, U. WERNER, U.
MOLLER, B. STAMMEN, D. BOTTGER, A. PONTY, M. KAISER, P. WAGNER & D.
MULLER NOVEL POTASSIUM CHANNEL OPENERS, 285 J. SOMBROEK, R. BERGMANN, R.
GERICKE & 1. LUES DRUGS ASSOCIATED WITH BONE FORMATION AND METABOLISM
METABOLIC BONE DISEASE; CURRENT THERAPIES AND FUTURE PROSPECTS WITH
BISPHOSPHONATES AND OTHER AGENTS, 293 F. H. EBETINO & R. G. G. RUSSELL
NOVEL VITAMIN D ANALOGUES IN THE CALCIPOTRIOL (MC 903) SERIES: SYNTHESIS
AND EFFECT OF SIDE CHAIN STRUCTURE ON THE SELECTIVE BIOLOGICAL ACTIONS,
299 M. J. CALVERLEY AN EFFICIENT, NON-PHOTOCHEMICAL SYNTHETIC APPROACH
TO VITAMIN D METABOLITES AND ANALOGUES, 307 J. STERLING, D. BARASCH, E.
SLOVIN, D. HIRSCH, D. LEONOV, A. SCHWARTZ & B. WEINER AGENTS AGAINST
INFECTIOUS DISEASES AND CANCER DESIGN AND SYNTHESIS OF NOVEL DNA-GYRASE
INHIBITORS, 315 C. HUBSCHWERLEN, P. PFLIEGER & I. KOMPIS HYPERICIN, A
POTENTIAL ANTI-AIDS DRUG, 321 D. LAVIE, D. FREEMAN, H. BOCK, J.
FLEISCHER, K. VAN KRANENBERG, Y. ITTAH, Y. MAZUR, G. LAVIE, L. LIEBES &
D. MERUELO AS-101 [AMMONIUM TRICHLORO(DIOXOETHYLENE-O,O -)TELLURATE] A
NEW IMMUNOMODULATOR FOR USE IN TREATMENT OF MALIGNANCIES AND AIDS, 329
M. ALBECK & B. SREDNI CYTOTOXIC GROUPS LINKED TO SYNTHETIC ESTROGENS,
333 K. KROHN, K. KULIKOWSKI, H. MULLER, M. PREISS & G. LECLERCQ
MEDICINAL PLANTS FROM CHINA CHINESE TRADITIONAL MEDICINE * A VALUABLE
FIELD TO BE EXPLORED, 343 H. LIANG CHEMICAL DRUG DELIVERY SYSTEMS,
BIOTRANSFORMATIONS AND PHARMACODYNAMICS DEVELOPMENT OF A LUNG-SELECTIVE
BRONCHODILATOR PRODRUG: BAMBUTEROL, 357 L. A. SVENSSON SITE- AND
STEREOSPECIFIC DRUG DELIVERY TO THE EYE, 361 A. SIMAY & N. BODOR
CONTENTS EVALUATION OF A NOVEL REDOX-BASED ESTROGEN CHEMICAL DELIVERY
SYSTEM FOR THE BRAIN, 369 M. H. RAHIMY, N. BODOR & J. W. SIMPKINS
PRODRUGS OF VALPROIC ACID, 377 M. BIALER FROM HANSCH TO HILDEBRAND: AN
ALTERNATIVE APPROACH TO PHARMACODYNAMICS, 383 S. COHEN TRANSMEMBRANE
DRUG TRANSPORT LIPOSOMES IN CANCER CHEMOTHERAPY: EXPERIMENTAL
STRATEGIES, 393 Y. BARENHOLZ & A. GABIZON IMPORTANCE OF BIOLOGICAL
MEMBRANES IN DRUG ACTION AND DEVELOPMENT, 397 J. K. SEYDEL, H. P.
CORDES, M. WIESE, M. KANSY & B. KUNZ SPECIAL TOPICS DISSOCIATION OF
PHARMACOLOGICAL EFFECTS IN CHIRAL DRUGS, 405 V. TORTORELLA RECENT
ADVANCES IN THE FIELD OF SATIETINS, 411 J. KNOLL NEW RETINOIDS FOR THE
TREATMENT OF DISORDERS OF EPIDERMAL DIFFERENTIATION, 419 B. SHROOT, J.
EUSTACHE, J. M. BERNARDON & W. R. PILGRIM INDEX, 425 ;
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| spellingShingle | Trends in medicinal chemistry '90 proceedings of the XIth International Symposium on Medicinal Chemistry, held in Jerusalem, Israel, 2 - 7 September 1990 Chemistry, Pharmaceutical Congresses Drug Design Congresses Drug Therapy Congresses Drugs Design Congresses Pharmaceutical chemistry Congresses Pharmazeutische Chemie (DE-588)4132158-3 gnd Pharmakologie (DE-588)4045687-0 gnd |
| subject_GND | (DE-588)4132158-3 (DE-588)4045687-0 (DE-588)1071861417 |
| title | Trends in medicinal chemistry '90 proceedings of the XIth International Symposium on Medicinal Chemistry, held in Jerusalem, Israel, 2 - 7 September 1990 |
| title_auth | Trends in medicinal chemistry '90 proceedings of the XIth International Symposium on Medicinal Chemistry, held in Jerusalem, Israel, 2 - 7 September 1990 |
| title_exact_search | Trends in medicinal chemistry '90 proceedings of the XIth International Symposium on Medicinal Chemistry, held in Jerusalem, Israel, 2 - 7 September 1990 |
| title_full | Trends in medicinal chemistry '90 proceedings of the XIth International Symposium on Medicinal Chemistry, held in Jerusalem, Israel, 2 - 7 September 1990 International Union of Pure and Applied Chemistry. Ed. by Shalom Sarel ... |
| title_fullStr | Trends in medicinal chemistry '90 proceedings of the XIth International Symposium on Medicinal Chemistry, held in Jerusalem, Israel, 2 - 7 September 1990 International Union of Pure and Applied Chemistry. Ed. by Shalom Sarel ... |
| title_full_unstemmed | Trends in medicinal chemistry '90 proceedings of the XIth International Symposium on Medicinal Chemistry, held in Jerusalem, Israel, 2 - 7 September 1990 International Union of Pure and Applied Chemistry. Ed. by Shalom Sarel ... |
| title_short | Trends in medicinal chemistry '90 |
| title_sort | trends in medicinal chemistry 90 proceedings of the xith international symposium on medicinal chemistry held in jerusalem israel 2 7 september 1990 |
| title_sub | proceedings of the XIth International Symposium on Medicinal Chemistry, held in Jerusalem, Israel, 2 - 7 September 1990 |
| topic | Chemistry, Pharmaceutical Congresses Drug Design Congresses Drug Therapy Congresses Drugs Design Congresses Pharmaceutical chemistry Congresses Pharmazeutische Chemie (DE-588)4132158-3 gnd Pharmakologie (DE-588)4045687-0 gnd |
| topic_facet | Chemistry, Pharmaceutical Congresses Drug Design Congresses Drug Therapy Congresses Drugs Design Congresses Pharmaceutical chemistry Congresses Pharmazeutische Chemie Pharmakologie Konferenzschrift 1990 Jerusalem |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=005539061&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT sarelsalom trendsinmedicinalchemistry90proceedingsofthexithinternationalsymposiumonmedicinalchemistryheldinjerusalemisrael27september1990 AT internationalsymposiumonmedicinalchemistryjerusalem trendsinmedicinalchemistry90proceedingsofthexithinternationalsymposiumonmedicinalchemistryheldinjerusalemisrael27september1990 |