Chemical aspects of enzyme biotechnology fundamentals ; [proceedings of the Texas A&M University, IUCCP Eighth Annual Symposium on Chemical Aspects of Enzyme Biotechnology: Fundamentals, held March 19 - 22, 1990, in College Station, Tex.]

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Veröffentlicht: New York u.a. Plenum Press 1990
Schriftenreihe:Industry university cooperative chemistry programm symposia
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Datensatz im Suchindex

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adam_text CONTENTS ENZYME MECHANISMS Effect of Metal Ions and Adenylylation State on the Energetics of the E. Coli Glutaminę Synthetase Reaction 1 Lynn M. Abell and Joseph J. Villafranca Structure-Function Relationships in Mandelate Racemase and Muconate Lactonizing Enzyme 9 John A. Gerlt, George L. Kenyon, John W. Kozarich, David T. Lin, David C. Neidhart, Gregory A. Petsko, Vincent M. Powers, Stephen C. Ransom, and Amy Y. Tsou An Enzyme-Targeted Herbicide-Design Program Based on EPSP Synthase: Chemical Mechanism and Glyphosate Inhibition Studies 23 James A. Sikorski, Karen S. Anderson, Darryl G. Cleary, Michael J. Miller, Paul D. Pansegrau, Joel E. Ream, R. Douglas Sainmons, and Kenneth A. Johnson Mechanism of Enzymatic Phosphotriesters Hydrolysis 41 Steve R. Caldwell and Frank M. Raushel PROTEIN FOLDING Proline Isomerization and Protein Folding 53 Christy Mac Kinnon, Sudha Veeraragharan, Isabelle Kreider, Michael J. Allen, John R. Liggins, and Barry T. Nail Increasing Enzyme Stability 65 C. Nick Pace A Study of Subunit Folding and Dimer Assembly In Vivo 77 Thomas O. Baldwin Characterization of a Transient intermediate in the Folding of Dihydrofolate Reducíase 87 С. Robert Matthews, Edward P. Garvey, and Jonathan Swank DESIGN AND REDESIGN OF ENZYMES AND PROTEINS From Biological Diversity to Structure-Function Analysis: Protein Engineering in Asparate Transcarbamoylase 95 James R. Wild, Janet K. Grimsley, Karen M. Kedzie, and Melinda Wales Catalytic Antibodies: Perspective and Prospects 111 Donald Hilvert NEW DRUGS BASED ON ENZYME MECHANISMS Potent and Selective Oxytocin Antagonists Obtained by Chemical Modification of a Streptomvces Silvensis Derived Cyclic Hexapeptide and by Total Synthesis 123 M.G. Bock, R.M.. DiPardo, P.D. Williams, R.D. Tung, J.M. Erb, N.P. Gould, W.L. Whitter, D.S. Perlow, G.F. Lundell, R.G. Ball, D.J. Pettibone, B.V. Clineschmidt, D.F. Veber, and R.M.. Freidinger Design of Peptide Ligands That Interact With Specific Membrane Receptors 135 Victor J. Hruby, T. Matsunaga, F. Al-Obeidi, G. Toth, C. Gehrig, and P.S. Hill ORGANIC SYNTHESIS WITH ENZYMES Stereoselective Synthesis of Biologically and Pharmacologically Important Chemical with Microbial Enzymes 151 Sakayu Shimizu and Hideaki Yamada Design and Development of Enzymatic Organic Synthesis 165 C.-H. Wong Enzymes as Catalysts in Carbohydrate Synthesis 179 Eric J. Toone, Yoshihiro Kobori, David С Myles, Akio Ozaki, Walther Schmid, Claus von der Osten, Anthony J. Sinskey, and George M. Whitesides Exploiting Enzymes Selectivity for the Synthesis of Biologically Active Compounds 197 Alexey L. Margolin VITAMIN B12 Perspectives on the Discovery of Vitamin Bj2 213 Karl A. Folkers Steric Course and Mechanism of Coenzyme B j 2-Dependent Rearrangements 223 János Rétey On the Mechanism of Action of Vitamin B j 2 · A Non-Free Radical Model for the Methylmalonyl-CoA - Succinyl-CoA Rearrangement 235 Paul Dowd, Guiyong Choi, Bogusława Wilk, Soo-Chang Choi, Songshen Zhang, and Rex E. Shepard Vitamin B j 2: The Biosynthesis of the Tetrapyrrole Ring: Mechanism and Molecular Biology 245 Peter M. Jordan Biosythesisof Vitamin В i2: Biosynthetic and Synthetic Researches 265 Alan R. Battersby On the Methylation Process and Cobalt Insertion in Cobyrinic Acid Biosynthesis 281 Gerhard Muller, K. Hlinený, E. Savvidis, F. Zipfel, J. Schmiedl, and E. Schneider Biochemical and Genetic Studies on Vitamin B12 Synthesis in Pseudomonas denitrificans 2 99 J. Crouzet, F. Blanche, B. Cameron, D. Thibaut, and L. Debussche Genetic Approaches to the Synthesis and Physiological Significance of B j 2 in Salmonella typhimurium 317 John R. Roth, Charlotte Grabau, and Thomas G. Doak Mechanistic and Evolutionary Aspects of Vitamin Bj2 Biosynthesis 333 A. Ian Scott APPENDIX Poster Titles 355 Index 357
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spellingShingle Chemical aspects of enzyme biotechnology fundamentals ; [proceedings of the Texas A&M University, IUCCP Eighth Annual Symposium on Chemical Aspects of Enzyme Biotechnology: Fundamentals, held March 19 - 22, 1990, in College Station, Tex.]
Biotechnologie (DE-588)4069491-4 gnd
Enzym (DE-588)4014988-2 gnd
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(DE-588)1071861417
title Chemical aspects of enzyme biotechnology fundamentals ; [proceedings of the Texas A&M University, IUCCP Eighth Annual Symposium on Chemical Aspects of Enzyme Biotechnology: Fundamentals, held March 19 - 22, 1990, in College Station, Tex.]
title_auth Chemical aspects of enzyme biotechnology fundamentals ; [proceedings of the Texas A&M University, IUCCP Eighth Annual Symposium on Chemical Aspects of Enzyme Biotechnology: Fundamentals, held March 19 - 22, 1990, in College Station, Tex.]
title_exact_search Chemical aspects of enzyme biotechnology fundamentals ; [proceedings of the Texas A&M University, IUCCP Eighth Annual Symposium on Chemical Aspects of Enzyme Biotechnology: Fundamentals, held March 19 - 22, 1990, in College Station, Tex.]
title_full Chemical aspects of enzyme biotechnology fundamentals ; [proceedings of the Texas A&M University, IUCCP Eighth Annual Symposium on Chemical Aspects of Enzyme Biotechnology: Fundamentals, held March 19 - 22, 1990, in College Station, Tex.] ed. by Thomas O. Baldwin ...
title_fullStr Chemical aspects of enzyme biotechnology fundamentals ; [proceedings of the Texas A&M University, IUCCP Eighth Annual Symposium on Chemical Aspects of Enzyme Biotechnology: Fundamentals, held March 19 - 22, 1990, in College Station, Tex.] ed. by Thomas O. Baldwin ...
title_full_unstemmed Chemical aspects of enzyme biotechnology fundamentals ; [proceedings of the Texas A&M University, IUCCP Eighth Annual Symposium on Chemical Aspects of Enzyme Biotechnology: Fundamentals, held March 19 - 22, 1990, in College Station, Tex.] ed. by Thomas O. Baldwin ...
title_short Chemical aspects of enzyme biotechnology
title_sort chemical aspects of enzyme biotechnology fundamentals proceedings of the texas a m university iuccp eighth annual symposium on chemical aspects of enzyme biotechnology fundamentals held march 19 22 1990 in college station tex
title_sub fundamentals ; [proceedings of the Texas A&M University, IUCCP Eighth Annual Symposium on Chemical Aspects of Enzyme Biotechnology: Fundamentals, held March 19 - 22, 1990, in College Station, Tex.]
topic Biotechnologie (DE-588)4069491-4 gnd
Enzym (DE-588)4014988-2 gnd
topic_facet Biotechnologie
Enzym
Konferenzschrift 1990 College Station Tex.
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