Depressive symptoms and problematic alcohol and other substance use in 1,476 gay, bisexual, and other men who have sex with men at three research sites in Kenya

OBJECTIVE:Information on mental health and substance use challenges among gay, bisexual, and other men who have sex with men (GBMSM) is needed to focus resources on these issues and optimize services for HIV prevention and care. We determined factors associated with depressive symptoms and problemat...

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Veröffentlicht in:AIDS (London) 2018-05
Hauptverfasser: Korhonen, Christine, Kimani, Makobu, Wahome, Elizabeth, Otieno, Fredrick, Okall, Duncan, Bailey, Robert C, Harper, Gary W, Lorway, Robert R, Doshi, Monika, Mathenge, John, Kimani, Joshua, Sanders, Eduard J, Graham, Susan M
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container_title AIDS (London)
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creator Korhonen, Christine
Kimani, Makobu
Wahome, Elizabeth
Otieno, Fredrick
Okall, Duncan
Bailey, Robert C
Harper, Gary W
Lorway, Robert R
Doshi, Monika
Mathenge, John
Kimani, Joshua
Sanders, Eduard J
Graham, Susan M
description OBJECTIVE:Information on mental health and substance use challenges among gay, bisexual, and other men who have sex with men (GBMSM) is needed to focus resources on these issues and optimize services for HIV prevention and care. We determined factors associated with depressive symptoms and problematic alcohol and other substance use among GBMSM in Kenya. METHODS:Self-identified GBMSM in three HIV research studies in Kenya provided information on depressive symptoms (PHQ-9), alcohol use (AUDIT), and other substance use (DAST-6). Associations were evaluated using mixed effects Poisson regression. RESULTS:Of 1,476 participants, 452 (31%) reported moderate to severe depressive symptoms (PHQ-9≥10), 637 (44%) hazardous alcohol use (AUDIT ≥8), and 749 (51%) problematic substance use (DAST-6 ≥1). Known HIV-positive status was not associated with these outcomes. Transactional sex was associated with AUDIT ≥8 (adjusted prevalence ratio [aPR] 1.34, 95% confidence interval [CI] 1.12–1.60). Childhood abuse and recent trauma were associated with PHQ-9 ≥10 (aPR 1.43, 95% CI 1.10–1.86 and aPR 2.43, 95% CI 1.91–3.09, respectively), AUDIT ≥8 (aPR 1.36, 95% CI 1.10–1.68 and aPR 1.60, 95% CI 1.33–1.93, respectively), and DAST-6 ≥1 (aPR 1.32, 95% CI 1.09–1.60 and aPR 1.35, 95% CI 1.14–1.59, respectively). CONCLUSIONS:GBMSM in rights-constrained settings need culturally appropriate services for treatment and prevention of mental health and substance use disorders, in addition to human rights advocacy to prevent abuse. Mental health and substance use screening and treatment or referral should be an integral part of programs, including HIV prevention and treatment programs, providing services to GBMSM.
doi_str_mv 10.1097/QAD.0000000000001847
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We determined factors associated with depressive symptoms and problematic alcohol and other substance use among GBMSM in Kenya. METHODS:Self-identified GBMSM in three HIV research studies in Kenya provided information on depressive symptoms (PHQ-9), alcohol use (AUDIT), and other substance use (DAST-6). Associations were evaluated using mixed effects Poisson regression. RESULTS:Of 1,476 participants, 452 (31%) reported moderate to severe depressive symptoms (PHQ-9≥10), 637 (44%) hazardous alcohol use (AUDIT ≥8), and 749 (51%) problematic substance use (DAST-6 ≥1). Known HIV-positive status was not associated with these outcomes. Transactional sex was associated with AUDIT ≥8 (adjusted prevalence ratio [aPR] 1.34, 95% confidence interval [CI] 1.12–1.60). Childhood abuse and recent trauma were associated with PHQ-9 ≥10 (aPR 1.43, 95% CI 1.10–1.86 and aPR 2.43, 95% CI 1.91–3.09, respectively), AUDIT ≥8 (aPR 1.36, 95% CI 1.10–1.68 and aPR 1.60, 95% CI 1.33–1.93, respectively), and DAST-6 ≥1 (aPR 1.32, 95% CI 1.09–1.60 and aPR 1.35, 95% CI 1.14–1.59, respectively). CONCLUSIONS:GBMSM in rights-constrained settings need culturally appropriate services for treatment and prevention of mental health and substance use disorders, in addition to human rights advocacy to prevent abuse. Mental health and substance use screening and treatment or referral should be an integral part of programs, including HIV prevention and treatment programs, providing services to GBMSM.</description><identifier>ISSN: 0269-9370</identifier><identifier>EISSN: 1473-5571</identifier><identifier>DOI: 10.1097/QAD.0000000000001847</identifier><language>eng</language><publisher>Copyright Wolters Kluwer Health, Inc</publisher><ispartof>AIDS (London), 2018-05</ispartof><rights>Copyright © 2018 Wolters Kluwer Health, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Korhonen, Christine</creatorcontrib><creatorcontrib>Kimani, Makobu</creatorcontrib><creatorcontrib>Wahome, Elizabeth</creatorcontrib><creatorcontrib>Otieno, Fredrick</creatorcontrib><creatorcontrib>Okall, Duncan</creatorcontrib><creatorcontrib>Bailey, Robert C</creatorcontrib><creatorcontrib>Harper, Gary W</creatorcontrib><creatorcontrib>Lorway, Robert R</creatorcontrib><creatorcontrib>Doshi, Monika</creatorcontrib><creatorcontrib>Mathenge, John</creatorcontrib><creatorcontrib>Kimani, Joshua</creatorcontrib><creatorcontrib>Sanders, Eduard J</creatorcontrib><creatorcontrib>Graham, Susan M</creatorcontrib><title>Depressive symptoms and problematic alcohol and other substance use in 1,476 gay, bisexual, and other men who have sex with men at three research sites in Kenya</title><title>AIDS (London)</title><description>OBJECTIVE:Information on mental health and substance use challenges among gay, bisexual, and other men who have sex with men (GBMSM) is needed to focus resources on these issues and optimize services for HIV prevention and care. We determined factors associated with depressive symptoms and problematic alcohol and other substance use among GBMSM in Kenya. METHODS:Self-identified GBMSM in three HIV research studies in Kenya provided information on depressive symptoms (PHQ-9), alcohol use (AUDIT), and other substance use (DAST-6). Associations were evaluated using mixed effects Poisson regression. RESULTS:Of 1,476 participants, 452 (31%) reported moderate to severe depressive symptoms (PHQ-9≥10), 637 (44%) hazardous alcohol use (AUDIT ≥8), and 749 (51%) problematic substance use (DAST-6 ≥1). Known HIV-positive status was not associated with these outcomes. Transactional sex was associated with AUDIT ≥8 (adjusted prevalence ratio [aPR] 1.34, 95% confidence interval [CI] 1.12–1.60). Childhood abuse and recent trauma were associated with PHQ-9 ≥10 (aPR 1.43, 95% CI 1.10–1.86 and aPR 2.43, 95% CI 1.91–3.09, respectively), AUDIT ≥8 (aPR 1.36, 95% CI 1.10–1.68 and aPR 1.60, 95% CI 1.33–1.93, respectively), and DAST-6 ≥1 (aPR 1.32, 95% CI 1.09–1.60 and aPR 1.35, 95% CI 1.14–1.59, respectively). CONCLUSIONS:GBMSM in rights-constrained settings need culturally appropriate services for treatment and prevention of mental health and substance use disorders, in addition to human rights advocacy to prevent abuse. Mental health and substance use screening and treatment or referral should be an integral part of programs, including HIV prevention and treatment programs, providing services to GBMSM.</description><issn>0269-9370</issn><issn>1473-5571</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNqlkE1OhEAQhTtGE_HnBi7qADB2CwywNI7GxJWJe1Jgabc2NOlqZLiNR5WZuJi4tTYveXn1qvIJcaXkSsmquH6-3azkwagyK45EpLIiTfK8UMcikjfrKqnSQp6KM-aPJZTLsozE94YGT8zmi4DnbgiuY8D-FQbvGksdBtMC2tZpZ_e-C5o88NhwwL4lGJnA9KDirFjDO84xNIZpO6KND_Id9TBpBxp3d2gLkwl672KAoD0RLF8Q-lYDm0C863yifsYLcfKGlunyV89F-XD_cveYTM4G8vxpx4l8rQlt0LWS9Y5IvRCp_xJJ_7H6A55IbTI</recordid><startdate>20180503</startdate><enddate>20180503</enddate><creator>Korhonen, Christine</creator><creator>Kimani, Makobu</creator><creator>Wahome, Elizabeth</creator><creator>Otieno, Fredrick</creator><creator>Okall, Duncan</creator><creator>Bailey, Robert C</creator><creator>Harper, Gary W</creator><creator>Lorway, Robert R</creator><creator>Doshi, Monika</creator><creator>Mathenge, John</creator><creator>Kimani, Joshua</creator><creator>Sanders, Eduard J</creator><creator>Graham, Susan M</creator><general>Copyright Wolters Kluwer Health, Inc</general><scope/></search><sort><creationdate>20180503</creationdate><title>Depressive symptoms and problematic alcohol and other substance use in 1,476 gay, bisexual, and other men who have sex with men at three research sites in Kenya</title><author>Korhonen, Christine ; Kimani, Makobu ; Wahome, Elizabeth ; Otieno, Fredrick ; Okall, Duncan ; Bailey, Robert C ; Harper, Gary W ; Lorway, Robert R ; Doshi, Monika ; Mathenge, John ; Kimani, Joshua ; Sanders, Eduard J ; Graham, Susan M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-wolterskluwer_health_10_1097_QAD_00000000000018473</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Korhonen, Christine</creatorcontrib><creatorcontrib>Kimani, Makobu</creatorcontrib><creatorcontrib>Wahome, Elizabeth</creatorcontrib><creatorcontrib>Otieno, Fredrick</creatorcontrib><creatorcontrib>Okall, Duncan</creatorcontrib><creatorcontrib>Bailey, Robert C</creatorcontrib><creatorcontrib>Harper, Gary W</creatorcontrib><creatorcontrib>Lorway, Robert R</creatorcontrib><creatorcontrib>Doshi, Monika</creatorcontrib><creatorcontrib>Mathenge, John</creatorcontrib><creatorcontrib>Kimani, Joshua</creatorcontrib><creatorcontrib>Sanders, Eduard J</creatorcontrib><creatorcontrib>Graham, Susan M</creatorcontrib><jtitle>AIDS (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Korhonen, Christine</au><au>Kimani, Makobu</au><au>Wahome, Elizabeth</au><au>Otieno, Fredrick</au><au>Okall, Duncan</au><au>Bailey, Robert C</au><au>Harper, Gary W</au><au>Lorway, Robert R</au><au>Doshi, Monika</au><au>Mathenge, John</au><au>Kimani, Joshua</au><au>Sanders, Eduard J</au><au>Graham, Susan M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Depressive symptoms and problematic alcohol and other substance use in 1,476 gay, bisexual, and other men who have sex with men at three research sites in Kenya</atitle><jtitle>AIDS (London)</jtitle><date>2018-05-03</date><risdate>2018</risdate><issn>0269-9370</issn><eissn>1473-5571</eissn><abstract>OBJECTIVE:Information on mental health and substance use challenges among gay, bisexual, and other men who have sex with men (GBMSM) is needed to focus resources on these issues and optimize services for HIV prevention and care. We determined factors associated with depressive symptoms and problematic alcohol and other substance use among GBMSM in Kenya. METHODS:Self-identified GBMSM in three HIV research studies in Kenya provided information on depressive symptoms (PHQ-9), alcohol use (AUDIT), and other substance use (DAST-6). Associations were evaluated using mixed effects Poisson regression. RESULTS:Of 1,476 participants, 452 (31%) reported moderate to severe depressive symptoms (PHQ-9≥10), 637 (44%) hazardous alcohol use (AUDIT ≥8), and 749 (51%) problematic substance use (DAST-6 ≥1). Known HIV-positive status was not associated with these outcomes. Transactional sex was associated with AUDIT ≥8 (adjusted prevalence ratio [aPR] 1.34, 95% confidence interval [CI] 1.12–1.60). Childhood abuse and recent trauma were associated with PHQ-9 ≥10 (aPR 1.43, 95% CI 1.10–1.86 and aPR 2.43, 95% CI 1.91–3.09, respectively), AUDIT ≥8 (aPR 1.36, 95% CI 1.10–1.68 and aPR 1.60, 95% CI 1.33–1.93, respectively), and DAST-6 ≥1 (aPR 1.32, 95% CI 1.09–1.60 and aPR 1.35, 95% CI 1.14–1.59, respectively). CONCLUSIONS:GBMSM in rights-constrained settings need culturally appropriate services for treatment and prevention of mental health and substance use disorders, in addition to human rights advocacy to prevent abuse. Mental health and substance use screening and treatment or referral should be an integral part of programs, including HIV prevention and treatment programs, providing services to GBMSM.</abstract><pub>Copyright Wolters Kluwer Health, Inc</pub><doi>10.1097/QAD.0000000000001847</doi></addata></record>
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title Depressive symptoms and problematic alcohol and other substance use in 1,476 gay, bisexual, and other men who have sex with men at three research sites in Kenya
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