Telomerase As a Therapeutic Target in Cardiovascular Disease

Shortened telomeres have been linked to numerous chronic diseases, most importantly coronary artery disease, but the underlying mechanisms remain ill defined. Loss-of-function mutations and deletions in telomerase both accelerate telomere shortening but do not necessarily lead to a clinical phenotyp...

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Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 2021-01
Hauptverfasser:	Hoffmann, Jedrzej, Richardson, Gavin, Haendeler, Judith, Altschmied, Joachim, Andrés, Vicente, Spyridopoulos, Ioakim
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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