Surgical left atrial appendage occlusion in patients with atrial fibrillation undergoing mechanical heart valve replacement
Background Surgical left atrial appendage occlusion (SLAAO) may be associated with a lower risk of thromboembolism in patients with atrial fibrillation undergoing cardiac surgery. However, evidence regarding the effectiveness of SLAAO in patients undergoing mechanical heart valve replacement (MHVR)...
Gespeichert in:
| Veröffentlicht in: | Chinese medical journal 2020-08, Vol.133 (16), p.1891-1899 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1899 |
|---|---|
| container_issue | 16 |
| container_start_page | 1891 |
| container_title | Chinese medical journal |
| container_volume | 133 |
| creator | Zheng, Ye Rao, Chen-Fei Chen, Si-Peng He, Li Hou, Jian-Feng Zheng, Zhe |
| description | Background Surgical left atrial appendage occlusion (SLAAO) may be associated with a lower risk of thromboembolism in patients with atrial fibrillation undergoing cardiac surgery. However, evidence regarding the effectiveness of SLAAO in patients undergoing mechanical heart valve replacement (MHVR) is lacking. Therefore, we aimed to evaluate the association between SLAAO and the cardiovascular outcomes in patients with atrial fibrillation undergoing MHVR. Methods We retrospectively analyzed data for 497 patients with atrial fibrillation; 27.6% of the patients underwent SLAAO, and the remainder of the patients did not (No-SLAAO group). The primary outcome was a composite of ischemic stroke, systemic embolism, and all-cause mortality. Cumulative event-free survival rates were estimated using Kaplan-Meier curves, and we performed multivariate Cox analyses to evaluate the association between SLAAO and outcomes. We used one-to-one propensity score matching to balance patients' baseline characteristics, and analyzed 120 matching pairs. Results Five patients died within 30 days postoperatively, and there were no significant differences between the two groups regarding in-hospital complications (allP > 0.05). After a median follow-up of 14 months, 14 primary events occurred. Kaplan-Meier curves showed no difference in the cumulative incidence of freedom from the primary outcome (log-rankP = 0.830), hemorrhagic events (log-rankP = 0.870), and the secondary outcome (log-rankP = 0.730), between the two groups. Multivariable Cox proportional hazards regression analysis showed no association between SLAAO and any outcome (allP > 0.05). After propensity score matching, cardiopulmonary bypass time and aortic cross-clamp time, and the postoperative length of stay were significantly longer in the SLAAO group (allP < 0.05); results were similar to the unadjusted analyses. Conclusions Concomitant SLAAO and MHVR was associated with longer length of stay, and cardiopulmonary bypass time and aortic cross-clamp time, but was not associated with additional protective effects against thromboembolic events and mortality during the 14-month follow-up. |
| doi_str_mv | 10.1097/CM9.0000000000000967 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_wolte</sourceid><recordid>TN_cdi_wolterskluwer_health_00029330-202008200-00001</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_757eb9170d1647bdbef0c70990c51f39</doaj_id><sourcerecordid>2480933478</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5471-d4134485151613a6d84fc4e7cac6cffee9caa6ac11c9b24a728f2ad22d5f939f3</originalsourceid><addsrcrecordid>eNqNkl2L1DAUhoso7jr6D0QK3gjSNUnz0dwIy-DHwooX6nVI05NOxkxTk3YG8c-bmdkdd_fKQmlpnvchJ32L4iVGFxhJ8W75RV6gu5fk4lFxThglFeMUPy7OUc15xaWUZ8WzlNYIEcYEf1qc1aQhnDJ8Xvz5NsfeGe1LD3Yq9RRdftfjCEOneyiDMX5OLgylG8pRTw6GKZU7N61uWeva6LzPSxmahw5iH9zQlxswKz0c1CvQcSq32m-hjDB6bWCTPc-LJ1b7BC9unovix8cP35efq-uvn66Wl9eVYVTgqqO4prRhmGGOa827hlpDQRhtuLEWQBqtuTYYG9kSqgVpLNEdIR2zspa2XhRXR28X9FqN0W10_K2CdurwIcRe5f0540EJJqCVWKAOcyrargWLjEBSIsOwrWV2vT-6xrndQGfyGFH7e9L7K4NbqT5slaCcEMyz4M2NIIZfM6RJbVwykA9wgDAnRWjNa0l5HnVRvH6ArsMch3xUmWqQrGsqmkzRI2ViSCmCPW0GI7VvispNUQ-bkmOv7g5yCt1WIwPNEdhBG2wy-c8bOGHZwgRCDa_3Qrx006EAyzAPU46-_f_ovwF2wU8Q008_7yCqXBo_rfY0yZOiiiCSQ_mujrG_I7fsQQ</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2480933478</pqid></control><display><type>article</type><title>Surgical left atrial appendage occlusion in patients with atrial fibrillation undergoing mechanical heart valve replacement</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Web of Science - Science Citation Index Expanded - 2020<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" /></source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Zheng, Ye ; Rao, Chen-Fei ; Chen, Si-Peng ; He, Li ; Hou, Jian-Feng ; Zheng, Zhe</creator><creatorcontrib>Zheng, Ye ; Rao, Chen-Fei ; Chen, Si-Peng ; He, Li ; Hou, Jian-Feng ; Zheng, Zhe</creatorcontrib><description>Background Surgical left atrial appendage occlusion (SLAAO) may be associated with a lower risk of thromboembolism in patients with atrial fibrillation undergoing cardiac surgery. However, evidence regarding the effectiveness of SLAAO in patients undergoing mechanical heart valve replacement (MHVR) is lacking. Therefore, we aimed to evaluate the association between SLAAO and the cardiovascular outcomes in patients with atrial fibrillation undergoing MHVR. Methods We retrospectively analyzed data for 497 patients with atrial fibrillation; 27.6% of the patients underwent SLAAO, and the remainder of the patients did not (No-SLAAO group). The primary outcome was a composite of ischemic stroke, systemic embolism, and all-cause mortality. Cumulative event-free survival rates were estimated using Kaplan-Meier curves, and we performed multivariate Cox analyses to evaluate the association between SLAAO and outcomes. We used one-to-one propensity score matching to balance patients' baseline characteristics, and analyzed 120 matching pairs. Results Five patients died within 30 days postoperatively, and there were no significant differences between the two groups regarding in-hospital complications (allP > 0.05). After a median follow-up of 14 months, 14 primary events occurred. Kaplan-Meier curves showed no difference in the cumulative incidence of freedom from the primary outcome (log-rankP = 0.830), hemorrhagic events (log-rankP = 0.870), and the secondary outcome (log-rankP = 0.730), between the two groups. Multivariable Cox proportional hazards regression analysis showed no association between SLAAO and any outcome (allP > 0.05). After propensity score matching, cardiopulmonary bypass time and aortic cross-clamp time, and the postoperative length of stay were significantly longer in the SLAAO group (allP < 0.05); results were similar to the unadjusted analyses. Conclusions Concomitant SLAAO and MHVR was associated with longer length of stay, and cardiopulmonary bypass time and aortic cross-clamp time, but was not associated with additional protective effects against thromboembolic events and mortality during the 14-month follow-up.</description><identifier>ISSN: 0366-6999</identifier><identifier>EISSN: 2542-5641</identifier><identifier>DOI: 10.1097/CM9.0000000000000967</identifier><identifier>PMID: 32826451</identifier><language>eng</language><publisher>PHILADELPHIA: Lippincott Williams & Wilkins</publisher><subject>Ablation ; Age ; Atrial Appendage - surgery ; Atrial Fibrillation - surgery ; Blood clots ; Cardiac arrhythmia ; Cardiac Surgical Procedures ; Cardiovascular disease ; Coronary vessels ; Creatinine ; Diabetes ; Embolisms ; General & Internal Medicine ; Heart failure ; Heart surgery ; Heart Valve Prosthesis Implantation ; Heart Valves ; Hospitals ; Humans ; Hypertension ; Kidneys ; Life Sciences & Biomedicine ; Medicine, General & Internal ; Mortality ; Original ; Postoperative Complications ; Retrospective Studies ; Risk Factors ; Science & Technology ; Software ; Standard deviation ; Stroke ; Surgical techniques ; Thromboembolism ; Treatment Outcome ; Variables ; Womens health</subject><ispartof>Chinese medical journal, 2020-08, Vol.133 (16), p.1891-1899</ispartof><rights>Lippincott Williams & Wilkins</rights><rights>Copyright © 2020 The Chinese Medical Association, produced by Wolters Kluwer, Inc. under the CC-BY-NC-ND license. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0 (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2020 The Chinese Medical Association, produced by Wolters Kluwer, Inc. under the CC-BY-NC-ND license. 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>5</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wos000570086300001</woscitedreferencesoriginalsourcerecordid><citedby>FETCH-LOGICAL-c5471-d4134485151613a6d84fc4e7cac6cffee9caa6ac11c9b24a728f2ad22d5f939f3</citedby><cites>FETCH-LOGICAL-c5471-d4134485151613a6d84fc4e7cac6cffee9caa6ac11c9b24a728f2ad22d5f939f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462216/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462216/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,865,886,2103,2115,27929,27930,28253,53796,53798</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32826451$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zheng, Ye</creatorcontrib><creatorcontrib>Rao, Chen-Fei</creatorcontrib><creatorcontrib>Chen, Si-Peng</creatorcontrib><creatorcontrib>He, Li</creatorcontrib><creatorcontrib>Hou, Jian-Feng</creatorcontrib><creatorcontrib>Zheng, Zhe</creatorcontrib><title>Surgical left atrial appendage occlusion in patients with atrial fibrillation undergoing mechanical heart valve replacement</title><title>Chinese medical journal</title><addtitle>CHINESE MED J-PEKING</addtitle><addtitle>Chin Med J (Engl)</addtitle><description>Background Surgical left atrial appendage occlusion (SLAAO) may be associated with a lower risk of thromboembolism in patients with atrial fibrillation undergoing cardiac surgery. However, evidence regarding the effectiveness of SLAAO in patients undergoing mechanical heart valve replacement (MHVR) is lacking. Therefore, we aimed to evaluate the association between SLAAO and the cardiovascular outcomes in patients with atrial fibrillation undergoing MHVR. Methods We retrospectively analyzed data for 497 patients with atrial fibrillation; 27.6% of the patients underwent SLAAO, and the remainder of the patients did not (No-SLAAO group). The primary outcome was a composite of ischemic stroke, systemic embolism, and all-cause mortality. Cumulative event-free survival rates were estimated using Kaplan-Meier curves, and we performed multivariate Cox analyses to evaluate the association between SLAAO and outcomes. We used one-to-one propensity score matching to balance patients' baseline characteristics, and analyzed 120 matching pairs. Results Five patients died within 30 days postoperatively, and there were no significant differences between the two groups regarding in-hospital complications (allP > 0.05). After a median follow-up of 14 months, 14 primary events occurred. Kaplan-Meier curves showed no difference in the cumulative incidence of freedom from the primary outcome (log-rankP = 0.830), hemorrhagic events (log-rankP = 0.870), and the secondary outcome (log-rankP = 0.730), between the two groups. Multivariable Cox proportional hazards regression analysis showed no association between SLAAO and any outcome (allP > 0.05). After propensity score matching, cardiopulmonary bypass time and aortic cross-clamp time, and the postoperative length of stay were significantly longer in the SLAAO group (allP < 0.05); results were similar to the unadjusted analyses. Conclusions Concomitant SLAAO and MHVR was associated with longer length of stay, and cardiopulmonary bypass time and aortic cross-clamp time, but was not associated with additional protective effects against thromboembolic events and mortality during the 14-month follow-up.</description><subject>Ablation</subject><subject>Age</subject><subject>Atrial Appendage - surgery</subject><subject>Atrial Fibrillation - surgery</subject><subject>Blood clots</subject><subject>Cardiac arrhythmia</subject><subject>Cardiac Surgical Procedures</subject><subject>Cardiovascular disease</subject><subject>Coronary vessels</subject><subject>Creatinine</subject><subject>Diabetes</subject><subject>Embolisms</subject><subject>General & Internal Medicine</subject><subject>Heart failure</subject><subject>Heart surgery</subject><subject>Heart Valve Prosthesis Implantation</subject><subject>Heart Valves</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Kidneys</subject><subject>Life Sciences & Biomedicine</subject><subject>Medicine, General & Internal</subject><subject>Mortality</subject><subject>Original</subject><subject>Postoperative Complications</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Science & Technology</subject><subject>Software</subject><subject>Standard deviation</subject><subject>Stroke</subject><subject>Surgical techniques</subject><subject>Thromboembolism</subject><subject>Treatment Outcome</subject><subject>Variables</subject><subject>Womens health</subject><issn>0366-6999</issn><issn>2542-5641</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>AOWDO</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>DOA</sourceid><recordid>eNqNkl2L1DAUhoso7jr6D0QK3gjSNUnz0dwIy-DHwooX6nVI05NOxkxTk3YG8c-bmdkdd_fKQmlpnvchJ32L4iVGFxhJ8W75RV6gu5fk4lFxThglFeMUPy7OUc15xaWUZ8WzlNYIEcYEf1qc1aQhnDJ8Xvz5NsfeGe1LD3Yq9RRdftfjCEOneyiDMX5OLgylG8pRTw6GKZU7N61uWeva6LzPSxmahw5iH9zQlxswKz0c1CvQcSq32m-hjDB6bWCTPc-LJ1b7BC9unovix8cP35efq-uvn66Wl9eVYVTgqqO4prRhmGGOa827hlpDQRhtuLEWQBqtuTYYG9kSqgVpLNEdIR2zspa2XhRXR28X9FqN0W10_K2CdurwIcRe5f0540EJJqCVWKAOcyrargWLjEBSIsOwrWV2vT-6xrndQGfyGFH7e9L7K4NbqT5slaCcEMyz4M2NIIZfM6RJbVwykA9wgDAnRWjNa0l5HnVRvH6ArsMch3xUmWqQrGsqmkzRI2ViSCmCPW0GI7VvispNUQ-bkmOv7g5yCt1WIwPNEdhBG2wy-c8bOGHZwgRCDa_3Qrx006EAyzAPU46-_f_ovwF2wU8Q008_7yCqXBo_rfY0yZOiiiCSQ_mujrG_I7fsQQ</recordid><startdate>20200820</startdate><enddate>20200820</enddate><creator>Zheng, Ye</creator><creator>Rao, Chen-Fei</creator><creator>Chen, Si-Peng</creator><creator>He, Li</creator><creator>Hou, Jian-Feng</creator><creator>Zheng, Zhe</creator><general>Lippincott Williams & Wilkins</general><general>Lippincott Williams & Wilkins Ovid Technologies</general><general>Wolters Kluwer</general><scope>AOWDO</scope><scope>BLEPL</scope><scope>DTL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20200820</creationdate><title>Surgical left atrial appendage occlusion in patients with atrial fibrillation undergoing mechanical heart valve replacement</title><author>Zheng, Ye ; Rao, Chen-Fei ; Chen, Si-Peng ; He, Li ; Hou, Jian-Feng ; Zheng, Zhe</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5471-d4134485151613a6d84fc4e7cac6cffee9caa6ac11c9b24a728f2ad22d5f939f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Ablation</topic><topic>Age</topic><topic>Atrial Appendage - surgery</topic><topic>Atrial Fibrillation - surgery</topic><topic>Blood clots</topic><topic>Cardiac arrhythmia</topic><topic>Cardiac Surgical Procedures</topic><topic>Cardiovascular disease</topic><topic>Coronary vessels</topic><topic>Creatinine</topic><topic>Diabetes</topic><topic>Embolisms</topic><topic>General & Internal Medicine</topic><topic>Heart failure</topic><topic>Heart surgery</topic><topic>Heart Valve Prosthesis Implantation</topic><topic>Heart Valves</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Kidneys</topic><topic>Life Sciences & Biomedicine</topic><topic>Medicine, General & Internal</topic><topic>Mortality</topic><topic>Original</topic><topic>Postoperative Complications</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Science & Technology</topic><topic>Software</topic><topic>Standard deviation</topic><topic>Stroke</topic><topic>Surgical techniques</topic><topic>Thromboembolism</topic><topic>Treatment Outcome</topic><topic>Variables</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zheng, Ye</creatorcontrib><creatorcontrib>Rao, Chen-Fei</creatorcontrib><creatorcontrib>Chen, Si-Peng</creatorcontrib><creatorcontrib>He, Li</creatorcontrib><creatorcontrib>Hou, Jian-Feng</creatorcontrib><creatorcontrib>Zheng, Zhe</creatorcontrib><collection>Web of Science - Science Citation Index Expanded - 2020</collection><collection>Web of Science Core Collection</collection><collection>Science Citation Index Expanded</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Chinese medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zheng, Ye</au><au>Rao, Chen-Fei</au><au>Chen, Si-Peng</au><au>He, Li</au><au>Hou, Jian-Feng</au><au>Zheng, Zhe</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Surgical left atrial appendage occlusion in patients with atrial fibrillation undergoing mechanical heart valve replacement</atitle><jtitle>Chinese medical journal</jtitle><stitle>CHINESE MED J-PEKING</stitle><addtitle>Chin Med J (Engl)</addtitle><date>2020-08-20</date><risdate>2020</risdate><volume>133</volume><issue>16</issue><spage>1891</spage><epage>1899</epage><pages>1891-1899</pages><issn>0366-6999</issn><eissn>2542-5641</eissn><abstract>Background Surgical left atrial appendage occlusion (SLAAO) may be associated with a lower risk of thromboembolism in patients with atrial fibrillation undergoing cardiac surgery. However, evidence regarding the effectiveness of SLAAO in patients undergoing mechanical heart valve replacement (MHVR) is lacking. Therefore, we aimed to evaluate the association between SLAAO and the cardiovascular outcomes in patients with atrial fibrillation undergoing MHVR. Methods We retrospectively analyzed data for 497 patients with atrial fibrillation; 27.6% of the patients underwent SLAAO, and the remainder of the patients did not (No-SLAAO group). The primary outcome was a composite of ischemic stroke, systemic embolism, and all-cause mortality. Cumulative event-free survival rates were estimated using Kaplan-Meier curves, and we performed multivariate Cox analyses to evaluate the association between SLAAO and outcomes. We used one-to-one propensity score matching to balance patients' baseline characteristics, and analyzed 120 matching pairs. Results Five patients died within 30 days postoperatively, and there were no significant differences between the two groups regarding in-hospital complications (allP > 0.05). After a median follow-up of 14 months, 14 primary events occurred. Kaplan-Meier curves showed no difference in the cumulative incidence of freedom from the primary outcome (log-rankP = 0.830), hemorrhagic events (log-rankP = 0.870), and the secondary outcome (log-rankP = 0.730), between the two groups. Multivariable Cox proportional hazards regression analysis showed no association between SLAAO and any outcome (allP > 0.05). After propensity score matching, cardiopulmonary bypass time and aortic cross-clamp time, and the postoperative length of stay were significantly longer in the SLAAO group (allP < 0.05); results were similar to the unadjusted analyses. Conclusions Concomitant SLAAO and MHVR was associated with longer length of stay, and cardiopulmonary bypass time and aortic cross-clamp time, but was not associated with additional protective effects against thromboembolic events and mortality during the 14-month follow-up.</abstract><cop>PHILADELPHIA</cop><pub>Lippincott Williams & Wilkins</pub><pmid>32826451</pmid><doi>10.1097/CM9.0000000000000967</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0366-6999 |
| ispartof | Chinese medical journal, 2020-08, Vol.133 (16), p.1891-1899 |
| issn | 0366-6999 2542-5641 |
| language | eng |
| recordid | cdi_wolterskluwer_health_00029330-202008200-00001 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Web of Science - Science Citation Index Expanded - 2020<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" />; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Ablation Age Atrial Appendage - surgery Atrial Fibrillation - surgery Blood clots Cardiac arrhythmia Cardiac Surgical Procedures Cardiovascular disease Coronary vessels Creatinine Diabetes Embolisms General & Internal Medicine Heart failure Heart surgery Heart Valve Prosthesis Implantation Heart Valves Hospitals Humans Hypertension Kidneys Life Sciences & Biomedicine Medicine, General & Internal Mortality Original Postoperative Complications Retrospective Studies Risk Factors Science & Technology Software Standard deviation Stroke Surgical techniques Thromboembolism Treatment Outcome Variables Womens health |
| title | Surgical left atrial appendage occlusion in patients with atrial fibrillation undergoing mechanical heart valve replacement |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-12T10%3A51%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_wolte&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Surgical%20left%20atrial%20appendage%20occlusion%20in%20patients%20with%20atrial%20fibrillation%20undergoing%20mechanical%20heart%20valve%20replacement&rft.jtitle=Chinese%20medical%20journal&rft.au=Zheng,%20Ye&rft.date=2020-08-20&rft.volume=133&rft.issue=16&rft.spage=1891&rft.epage=1899&rft.pages=1891-1899&rft.issn=0366-6999&rft.eissn=2542-5641&rft_id=info:doi/10.1097/CM9.0000000000000967&rft_dat=%3Cproquest_wolte%3E2480933478%3C/proquest_wolte%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2480933478&rft_id=info:pmid/32826451&rft_doaj_id=oai_doaj_org_article_757eb9170d1647bdbef0c70990c51f39&rfr_iscdi=true |