Intrathecal delivery of hydromorphone vs morphine for refractory cancer pain: a multicenter, randomized, single-blind, controlled noninferiority trial

Hydromorphone is an alternative to morphine for intrathecal drug delivery system to treat refractory cancer pain; however, there is not enough clinical evidence to prove it. In our study, 233 patients from 12 different pain management centers across China were enrolled, 121 and 112 in the intratheca...

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Veröffentlicht in:	Pain (Amsterdam) 2020-11, Vol.161 (11), p.2502-2510
Hauptverfasser:	Ma, Ke, Jin, Yi, Wang, Lin, Feng, Zhi-Ying, Song, Tao, Yang, Xiao-Qiu, Chen, Fu-Qiang, Duan, Bao-Lin, Huang, You-Qing, Xie, Guang-Lun, Bao, Hong-Guang, Wang, Kun, Xu, Jiang-Tao, Lu, Yan, Liu, Yan-Qing
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics, Opioid - therapeutic use Cancer Pain - drug therapy China Double-Blind Method Humans Hydromorphone - therapeutic use Injections, Spinal Morphine - therapeutic use Neoplasms - complications Neoplasms - drug therapy Pain, Postoperative - drug therapy Single-Blind Method
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