Decreased 11β-Hydroxysteroid Dehydrogenase Type 2 Expression in the Kidney May Contribute to Nicotine/Smoking-Induced Blood Pressure Elevation in Mice

Chronic nicotine exposure significantly increases hypertensive risk in smokers, but the underlying mechanisms are poorly understood. In the kidneys, 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) catalyzes the conversion from active into inactive glucocorticoids and plays a pivotal role in the r...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2021-04
Hauptverfasser:	Wang, Ying, Wang, Jian, Yang, Rong, Wang, Piwen, Porche, Rene, Kim, Samuel, Lutfy, Kabirullah, Liu, Limei, Friedman, Theodore C., Jiang, Meisheng, Liu, Yanjun
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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