G-Protein beta 3 Subunit Gene (GNB3) Variant in Causation of Essential Hypertension

Essential hypertensives display enhanced signal transduction through pertussis toxin-sensitive G proteins. The T allele of a C825T variant in exon 10 of the G protein beta 3 subunit gene (GNB3) induces formation of a splice variant (G beta 3-s) with enhanced activity. The T allele of GNB3 was shown...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 1998-12, Vol.32 (6), p.1094-1097
Hauptverfasser:	Benjafield, Adam V, Jeyasingam, Cheryl L, Nyholt, Dale R, Griffiths, Lyn R, Morris, Brian J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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