Abstract 12305: Exercise Capacity and Chronotropic Incompetence in Patients After Mitral Valve Surgery
IntroductionChronotropic incompetence (CI) is sometimes observed during exercise in patients who underwent cardiac surgery, however, little is known concerning the differences between patients with mitral valve (MV) and aortic valve (AV) surgery.HypothesisBecause the possibility exists that cardiac...
Gespeichert in:
| Veröffentlicht in: | Circulation (New York, N.Y.) N.Y.), 2019-11, Vol.140 (Suppl_1 Suppl 1), p.A12305-A12305 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | A12305 |
|---|---|
| container_issue | Suppl_1 Suppl 1 |
| container_start_page | A12305 |
| container_title | Circulation (New York, N.Y.) |
| container_volume | 140 |
| creator | Kanazawa, Masanori Toyoda, Maiko Seki, Takahiro Iguchi, Atsuhiro Takahashi, Seisho Kagaya, Yuta Saito, Hiroki Sato, Kenjiro Ito, Koki Miura, Masanobu Kondo, Masateru Kawatsu, Satoshi Endo, Hideaki Oda, Katsuhiko Nakamura, Akihiro |
| description | IntroductionChronotropic incompetence (CI) is sometimes observed during exercise in patients who underwent cardiac surgery, however, little is known concerning the differences between patients with mitral valve (MV) and aortic valve (AV) surgery.HypothesisBecause the possibility exists that cardiac sympathetic nerves could be impaired by left atrium incision, we hypothesized that the incidence of CI was higher in patients with MV surgery (Mitral Valve Replacement and Mitral Valvuloplasty) as compared with those with AV surgery (Aortic Valve Replacement). And if so, which factor determines the exercise capacity of patients after MV surgery.MethodsWe performed cardiopulmonary exercise testing by ramp loading with ergometer exercise in total 52 patients who had undergone elective cardiac valve operation (19 patients with MV surgery, age 59.8 ± 10.2 years; 33 patients with AV surgery, age 63.5 ± 12.4 years). We analyzed chronotropic response index, peak oxygen uptake (peak VO2), peak oxygen pulse (peak VO2/HR), and blood hemoglobin concentration (Hb).ResultsThe value of chronotropic response index was significantly decreased in the patients with MV surgery compared with those with AV surgery (MV; 0.19±0.11 vs. AV; 0.40±0.18, p |
| doi_str_mv | 10.1161/circ.140.suppl_1.12305 |
| format | Article |
| fullrecord | <record><control><sourceid>wolterskluwer</sourceid><recordid>TN_cdi_wolterskluwer_health_00003017-201911191-01325</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>00003017-201911191-01325</sourcerecordid><originalsourceid>FETCH-wolterskluwer_health_00003017-201911191-013253</originalsourceid><addsrcrecordid>eNqdjsFKxDAURYMoWEd_Qd4PpOYlzZS6G8qILgYEZbYlxlcbjWlJUsf5e4v4BS4uh7s4l8vYNYoScY031kVbYiXKNE-T77BEqYQ-YQVqWfFKq-aUFUKIhtdKynN2kdL7Uteq1gXrNy8pR2Mz_Fq3sP2maF0iaM1krMtHMOEV2iGOYcxxnJyFh2DHz4kyBUvgAjya7CjkBJs-U4SdWwY97I3_Inia4xvF4yU7641PdPXHFavuts_tPT-MfnHSh58PFLuBjM9Dt7wTSmDNpcAGcQkXqKRW_9R-AOtRVx0</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Abstract 12305: Exercise Capacity and Chronotropic Incompetence in Patients After Mitral Valve Surgery</title><source>American Heart Association Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Journals@Ovid Ovid Autoload</source><creator>Kanazawa, Masanori ; Toyoda, Maiko ; Seki, Takahiro ; Iguchi, Atsuhiro ; Takahashi, Seisho ; Kagaya, Yuta ; Saito, Hiroki ; Sato, Kenjiro ; Ito, Koki ; Miura, Masanobu ; Kondo, Masateru ; Kawatsu, Satoshi ; Endo, Hideaki ; Oda, Katsuhiko ; Nakamura, Akihiro</creator><creatorcontrib>Kanazawa, Masanori ; Toyoda, Maiko ; Seki, Takahiro ; Iguchi, Atsuhiro ; Takahashi, Seisho ; Kagaya, Yuta ; Saito, Hiroki ; Sato, Kenjiro ; Ito, Koki ; Miura, Masanobu ; Kondo, Masateru ; Kawatsu, Satoshi ; Endo, Hideaki ; Oda, Katsuhiko ; Nakamura, Akihiro</creatorcontrib><description>IntroductionChronotropic incompetence (CI) is sometimes observed during exercise in patients who underwent cardiac surgery, however, little is known concerning the differences between patients with mitral valve (MV) and aortic valve (AV) surgery.HypothesisBecause the possibility exists that cardiac sympathetic nerves could be impaired by left atrium incision, we hypothesized that the incidence of CI was higher in patients with MV surgery (Mitral Valve Replacement and Mitral Valvuloplasty) as compared with those with AV surgery (Aortic Valve Replacement). And if so, which factor determines the exercise capacity of patients after MV surgery.MethodsWe performed cardiopulmonary exercise testing by ramp loading with ergometer exercise in total 52 patients who had undergone elective cardiac valve operation (19 patients with MV surgery, age 59.8 ± 10.2 years; 33 patients with AV surgery, age 63.5 ± 12.4 years). We analyzed chronotropic response index, peak oxygen uptake (peak VO2), peak oxygen pulse (peak VO2/HR), and blood hemoglobin concentration (Hb).ResultsThe value of chronotropic response index was significantly decreased in the patients with MV surgery compared with those with AV surgery (MV; 0.19±0.11 vs. AV; 0.40±0.18, p<0.001). Peak VO2, peak VO2/HR and Hb were not significantly different between patients with MV and those with AV surgery. Patients with MV surgery showed a correlation between peak VO2 and Hb (r=0.56, p<0.05), and a strong correlation between peak VO2 and peak VO2/HR (r=0.89, p<0.001), but not in those with AV surgery.ConclusionsThe present study demonstrated that higher incidence of CI was shown in patients with MV surgery as compared with AV surgery. The exercise capacity of patients with MV surgery was determined by peak VO2/HR and Hb. These results suggest that 1) left atrium incision impairs cardiac sympathetic nerves and causes CI, 2) peak VO2/HR which is consisted of arterio-venous oxygen difference and Hb is critical indicator for exercise capacity in patients with MV surgery with CI.</description><identifier>ISSN: 0009-7322</identifier><identifier>EISSN: 1524-4539</identifier><identifier>DOI: 10.1161/circ.140.suppl_1.12305</identifier><language>eng</language><publisher>by the American College of Cardiology Foundation and the American Heart Association, Inc</publisher><ispartof>Circulation (New York, N.Y.), 2019-11, Vol.140 (Suppl_1 Suppl 1), p.A12305-A12305</ispartof><rights>2019 by the American College of Cardiology Foundation and the American Heart Association, Inc.</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Kanazawa, Masanori</creatorcontrib><creatorcontrib>Toyoda, Maiko</creatorcontrib><creatorcontrib>Seki, Takahiro</creatorcontrib><creatorcontrib>Iguchi, Atsuhiro</creatorcontrib><creatorcontrib>Takahashi, Seisho</creatorcontrib><creatorcontrib>Kagaya, Yuta</creatorcontrib><creatorcontrib>Saito, Hiroki</creatorcontrib><creatorcontrib>Sato, Kenjiro</creatorcontrib><creatorcontrib>Ito, Koki</creatorcontrib><creatorcontrib>Miura, Masanobu</creatorcontrib><creatorcontrib>Kondo, Masateru</creatorcontrib><creatorcontrib>Kawatsu, Satoshi</creatorcontrib><creatorcontrib>Endo, Hideaki</creatorcontrib><creatorcontrib>Oda, Katsuhiko</creatorcontrib><creatorcontrib>Nakamura, Akihiro</creatorcontrib><title>Abstract 12305: Exercise Capacity and Chronotropic Incompetence in Patients After Mitral Valve Surgery</title><title>Circulation (New York, N.Y.)</title><description>IntroductionChronotropic incompetence (CI) is sometimes observed during exercise in patients who underwent cardiac surgery, however, little is known concerning the differences between patients with mitral valve (MV) and aortic valve (AV) surgery.HypothesisBecause the possibility exists that cardiac sympathetic nerves could be impaired by left atrium incision, we hypothesized that the incidence of CI was higher in patients with MV surgery (Mitral Valve Replacement and Mitral Valvuloplasty) as compared with those with AV surgery (Aortic Valve Replacement). And if so, which factor determines the exercise capacity of patients after MV surgery.MethodsWe performed cardiopulmonary exercise testing by ramp loading with ergometer exercise in total 52 patients who had undergone elective cardiac valve operation (19 patients with MV surgery, age 59.8 ± 10.2 years; 33 patients with AV surgery, age 63.5 ± 12.4 years). We analyzed chronotropic response index, peak oxygen uptake (peak VO2), peak oxygen pulse (peak VO2/HR), and blood hemoglobin concentration (Hb).ResultsThe value of chronotropic response index was significantly decreased in the patients with MV surgery compared with those with AV surgery (MV; 0.19±0.11 vs. AV; 0.40±0.18, p<0.001). Peak VO2, peak VO2/HR and Hb were not significantly different between patients with MV and those with AV surgery. Patients with MV surgery showed a correlation between peak VO2 and Hb (r=0.56, p<0.05), and a strong correlation between peak VO2 and peak VO2/HR (r=0.89, p<0.001), but not in those with AV surgery.ConclusionsThe present study demonstrated that higher incidence of CI was shown in patients with MV surgery as compared with AV surgery. The exercise capacity of patients with MV surgery was determined by peak VO2/HR and Hb. These results suggest that 1) left atrium incision impairs cardiac sympathetic nerves and causes CI, 2) peak VO2/HR which is consisted of arterio-venous oxygen difference and Hb is critical indicator for exercise capacity in patients with MV surgery with CI.</description><issn>0009-7322</issn><issn>1524-4539</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNqdjsFKxDAURYMoWEd_Qd4PpOYlzZS6G8qILgYEZbYlxlcbjWlJUsf5e4v4BS4uh7s4l8vYNYoScY031kVbYiXKNE-T77BEqYQ-YQVqWfFKq-aUFUKIhtdKynN2kdL7Uteq1gXrNy8pR2Mz_Fq3sP2maF0iaM1krMtHMOEV2iGOYcxxnJyFh2DHz4kyBUvgAjya7CjkBJs-U4SdWwY97I3_Inia4xvF4yU7641PdPXHFavuts_tPT-MfnHSh58PFLuBjM9Dt7wTSmDNpcAGcQkXqKRW_9R-AOtRVx0</recordid><startdate>20191119</startdate><enddate>20191119</enddate><creator>Kanazawa, Masanori</creator><creator>Toyoda, Maiko</creator><creator>Seki, Takahiro</creator><creator>Iguchi, Atsuhiro</creator><creator>Takahashi, Seisho</creator><creator>Kagaya, Yuta</creator><creator>Saito, Hiroki</creator><creator>Sato, Kenjiro</creator><creator>Ito, Koki</creator><creator>Miura, Masanobu</creator><creator>Kondo, Masateru</creator><creator>Kawatsu, Satoshi</creator><creator>Endo, Hideaki</creator><creator>Oda, Katsuhiko</creator><creator>Nakamura, Akihiro</creator><general>by the American College of Cardiology Foundation and the American Heart Association, Inc</general><scope/></search><sort><creationdate>20191119</creationdate><title>Abstract 12305: Exercise Capacity and Chronotropic Incompetence in Patients After Mitral Valve Surgery</title><author>Kanazawa, Masanori ; Toyoda, Maiko ; Seki, Takahiro ; Iguchi, Atsuhiro ; Takahashi, Seisho ; Kagaya, Yuta ; Saito, Hiroki ; Sato, Kenjiro ; Ito, Koki ; Miura, Masanobu ; Kondo, Masateru ; Kawatsu, Satoshi ; Endo, Hideaki ; Oda, Katsuhiko ; Nakamura, Akihiro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-wolterskluwer_health_00003017-201911191-013253</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Kanazawa, Masanori</creatorcontrib><creatorcontrib>Toyoda, Maiko</creatorcontrib><creatorcontrib>Seki, Takahiro</creatorcontrib><creatorcontrib>Iguchi, Atsuhiro</creatorcontrib><creatorcontrib>Takahashi, Seisho</creatorcontrib><creatorcontrib>Kagaya, Yuta</creatorcontrib><creatorcontrib>Saito, Hiroki</creatorcontrib><creatorcontrib>Sato, Kenjiro</creatorcontrib><creatorcontrib>Ito, Koki</creatorcontrib><creatorcontrib>Miura, Masanobu</creatorcontrib><creatorcontrib>Kondo, Masateru</creatorcontrib><creatorcontrib>Kawatsu, Satoshi</creatorcontrib><creatorcontrib>Endo, Hideaki</creatorcontrib><creatorcontrib>Oda, Katsuhiko</creatorcontrib><creatorcontrib>Nakamura, Akihiro</creatorcontrib><jtitle>Circulation (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kanazawa, Masanori</au><au>Toyoda, Maiko</au><au>Seki, Takahiro</au><au>Iguchi, Atsuhiro</au><au>Takahashi, Seisho</au><au>Kagaya, Yuta</au><au>Saito, Hiroki</au><au>Sato, Kenjiro</au><au>Ito, Koki</au><au>Miura, Masanobu</au><au>Kondo, Masateru</au><au>Kawatsu, Satoshi</au><au>Endo, Hideaki</au><au>Oda, Katsuhiko</au><au>Nakamura, Akihiro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Abstract 12305: Exercise Capacity and Chronotropic Incompetence in Patients After Mitral Valve Surgery</atitle><jtitle>Circulation (New York, N.Y.)</jtitle><date>2019-11-19</date><risdate>2019</risdate><volume>140</volume><issue>Suppl_1 Suppl 1</issue><spage>A12305</spage><epage>A12305</epage><pages>A12305-A12305</pages><issn>0009-7322</issn><eissn>1524-4539</eissn><abstract>IntroductionChronotropic incompetence (CI) is sometimes observed during exercise in patients who underwent cardiac surgery, however, little is known concerning the differences between patients with mitral valve (MV) and aortic valve (AV) surgery.HypothesisBecause the possibility exists that cardiac sympathetic nerves could be impaired by left atrium incision, we hypothesized that the incidence of CI was higher in patients with MV surgery (Mitral Valve Replacement and Mitral Valvuloplasty) as compared with those with AV surgery (Aortic Valve Replacement). And if so, which factor determines the exercise capacity of patients after MV surgery.MethodsWe performed cardiopulmonary exercise testing by ramp loading with ergometer exercise in total 52 patients who had undergone elective cardiac valve operation (19 patients with MV surgery, age 59.8 ± 10.2 years; 33 patients with AV surgery, age 63.5 ± 12.4 years). We analyzed chronotropic response index, peak oxygen uptake (peak VO2), peak oxygen pulse (peak VO2/HR), and blood hemoglobin concentration (Hb).ResultsThe value of chronotropic response index was significantly decreased in the patients with MV surgery compared with those with AV surgery (MV; 0.19±0.11 vs. AV; 0.40±0.18, p<0.001). Peak VO2, peak VO2/HR and Hb were not significantly different between patients with MV and those with AV surgery. Patients with MV surgery showed a correlation between peak VO2 and Hb (r=0.56, p<0.05), and a strong correlation between peak VO2 and peak VO2/HR (r=0.89, p<0.001), but not in those with AV surgery.ConclusionsThe present study demonstrated that higher incidence of CI was shown in patients with MV surgery as compared with AV surgery. The exercise capacity of patients with MV surgery was determined by peak VO2/HR and Hb. These results suggest that 1) left atrium incision impairs cardiac sympathetic nerves and causes CI, 2) peak VO2/HR which is consisted of arterio-venous oxygen difference and Hb is critical indicator for exercise capacity in patients with MV surgery with CI.</abstract><pub>by the American College of Cardiology Foundation and the American Heart Association, Inc</pub><doi>10.1161/circ.140.suppl_1.12305</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0009-7322 |
| ispartof | Circulation (New York, N.Y.), 2019-11, Vol.140 (Suppl_1 Suppl 1), p.A12305-A12305 |
| issn | 0009-7322 1524-4539 |
| language | eng |
| recordid | cdi_wolterskluwer_health_00003017-201911191-01325 |
| source | American Heart Association Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Ovid Autoload |
| title | Abstract 12305: Exercise Capacity and Chronotropic Incompetence in Patients After Mitral Valve Surgery |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-22T18%3A26%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-wolterskluwer&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Abstract%2012305:%20Exercise%20Capacity%20and%20Chronotropic%20Incompetence%20in%20Patients%20After%20Mitral%20Valve%20Surgery&rft.jtitle=Circulation%20(New%20York,%20N.Y.)&rft.au=Kanazawa,%20Masanori&rft.date=2019-11-19&rft.volume=140&rft.issue=Suppl_1%20Suppl%201&rft.spage=A12305&rft.epage=A12305&rft.pages=A12305-A12305&rft.issn=0009-7322&rft.eissn=1524-4539&rft_id=info:doi/10.1161/circ.140.suppl_1.12305&rft_dat=%3Cwolterskluwer%3E00003017-201911191-01325%3C/wolterskluwer%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |