Abstract 11894: Long-term Embolic Outcomes After Detection of Left Ventricular Thrombus by Late Gadolinium Enhancement Cardiovascular Magnetic Resonance Imaging: A Matched Cohort Study

IntroductionLate gadolinium enhancement cardiovascular magnetic resonance imaging (LGE CMR) is more sensitive than echocardiography for the detection of intracardiac thrombus due to its unique ability to identify thrombus based on tissue characteristics related to avascularity. However, the prognostic significance of left ventricular (LV) thrombus detected by LGE CMR is unknown. We aimed to determine long-term embolic outcomes in patients with LV thrombus detected by LGE CMR.MethodsWe performed a matched cohort study of consecutive adult patients with LV thrombus detected by LGE CMR who were matched on the date of CMR, age, and left ventricular ejection fraction (LVEF) to up to 3 non-LV thrombus patients. We investigated the incidence of a composite of embolic eventsstroke, transient ischemic attack, or extracranial systemic arterial embolism, up to 8 years after the CMR. We also compared outcomes among patients with LV thrombus detected by LGE CMR stratified by whether the LV thrombus was also detected by echocardiography or not.ResultsOf 157 LV thrombus patients, 155 were matched to 400 non-LV thrombus patients. Over a median follow-up of 3.3 years, the cumulative incidence of embolic events in LV thrombus patients was significantly higher than in the matched non-LV thrombus patients (p