Abstract 12595: Individuals Identified Genome-First With Truncating Variants in Titin Have Increased Prevalence and Distinct Etiology of Heart Failure

IntroductionTruncating variants in the TTN gene (TTNtv) are a major contributor to heritable forms of dilated cardiomyopathy (DCM); however, high prevalence in the general population presents a challenge to clinical interpretation. We have found that—when ascertained genome-first—individuals with TT...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2018-11, Vol.138 (Suppl_1 Suppl 1), p.A12595-A12595
Hauptverfasser:	Demerdash, Amin M, Chen, Jing, Jing, Linyuan, Fornwalt, Brandon K, Haggerty, Christopher M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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