Mechanism of Vascular Smooth Muscle Relaxation by Estrogen in Depolarized Rat and Mouse Aorta: Role of Nuclear Estrogen Receptor and Ca sup 2+ Uptake

17 beta-Estradiol induces vasodilation in vitro and in vivo, which has been suggested to contribute to the cardiovascular protection by this ovarian steroid hormone. However, the exact mechanism of vasorelaxation by estrogens remains to be elucidated. In this study, we analyzed the potential role of...

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Veröffentlicht in:Circulation research 1997-08, Vol.81 (2), p.242-248
Hauptverfasser: Freay, Ana D, Curtis, Sylvia W, Korach, Kenneth S, Rubanyi, Gabor M
Format: Artikel
Sprache:eng
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