alpha1-Adrenergic Receptor Stimulation Decreases Maximum Shortening Velocity of Skinned Single Ventricular Myocytes From Rats

alpha1-Adrenergic agonists have negative inotropic effects on mammalian myocardium under some conditions, and biochemical experiments measuring the Ca plus-activated actomyosin ATPase activity of myofibrillar preparations suggest that this may result from a decrease in cross-bridge cycling rate caus...

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Veröffentlicht in:	Circulation research 1995-07, Vol.77 (1), p.114-120
Hauptverfasser:	Strang, Kevin T, Moss, Richard L
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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