Fibrinogen Concentrate as an Alternative to Cryoprecipitate in a Postcardiopulmonary Transfusion Algorithm in Infants Undergoing Cardiac Surgery: A Prospective Randomized Controlled Trial

BACKGROUND:Infants undergoing cardiac surgery are at risk for bleeding and massive transfusion due to an immature coagulation system, complex surgeries, and cardiopulmonary bypass (CPB) effects. Hemodilution from CPB promotes an acquired hypofibrinogenemia that results in impaired fibrin formation,...

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Veröffentlicht in:	Anesthesia and analgesia 2020-03, Vol.130 (3), p.740-751
Hauptverfasser:	Downey, Laura A., Andrews, Jennifer, Hedlin, Haley, Kamra, Komal, McKenzie, E. Dean, Hanley, Frank L., Williams, Glyn D., Guzzetta, Nina A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Afibrinogenemia - blood Afibrinogenemia - drug therapy Afibrinogenemia - etiology Age Factors Algorithms Blood Coagulation - drug effects Blood Loss, Surgical - prevention & control Blood Transfusion Cardiac Surgical Procedures - adverse effects Clinical Protocols Coagulants - administration & dosage Coagulants - adverse effects Factor VIII - administration & dosage Factor VIII - adverse effects Female Fibrinogen - administration & dosage Fibrinogen - adverse effects Humans Infant Male Postoperative Hemorrhage - blood Postoperative Hemorrhage - etiology Postoperative Hemorrhage - therapy Prospective Studies Risk Factors Time Factors Treatment Outcome United States
Online-Zugang:	Volltext
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