A flattening filter free photon treatment concept evaluation with Monte Carlo
In principle, the concept of flat initial radiation-dose distribution across the beam is unnecessary for intensity modulated radiation therapy. Dynamic leaf positioning during irradiation could appropriately adjust the fluence distribution of an unflattened beam that is peaked in the center and deli...
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Veröffentlicht in: | Medical physics (Lancaster) 2006-06, Vol.33 (6), p.1595-1602 |
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description | In principle, the concept of flat initial radiation-dose distribution across the beam is unnecessary for intensity modulated radiation therapy. Dynamic leaf positioning during irradiation could appropriately adjust the fluence distribution of an unflattened beam that is peaked in the center and deliver the desired uniform or nonuniform dose distribution. Removing the flattening filter could lead to reduced treatment time through higher dose rates and reduced scatter, because there would be substantially less material in the beam; and possibly other dosimetric and clinical advantages. This work aims to evaluate the properties of a flattening filter free clinical accelerator and to investigate its possible advantages in clinical intensity modulated radiation therapy applications by simulating a Varian 2100-based treatment delivery system with Monte Carlo techniques. Several depth-dose curves and lateral dose distribution profiles have been created for various field sizes, with and without the flattening filter. Data computed with this model were used to evaluate the overall quality of such a system in terms of changes in dose rate, photon and electron fluence, and reduction in out-of-field stray dose from the scattered components and were compared to the corresponding data for a standard treatment head with a flattening filter. The results of the simulations of the flattening filter free system show that a substantial increase in dose rate can be achieved, which would reduce the beam on time and decrease the out-of-field dose for patients due to reduced head-leakage dose. Also close to the treatment field edge, a significant improvement in out-of-field dose could be observed for small fields, which can be attributed to the change in the photon spectra, when the flattening filter is removed from the beamline. |
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N. ; Pönisch, F. ; Dong, L. ; Liu, H. ; Mohan, R.</creator><creatorcontrib>Titt, U. ; Vassiliev, O. N. ; Pönisch, F. ; Dong, L. ; Liu, H. ; Mohan, R.</creatorcontrib><description>In principle, the concept of flat initial radiation-dose distribution across the beam is unnecessary for intensity modulated radiation therapy. Dynamic leaf positioning during irradiation could appropriately adjust the fluence distribution of an unflattened beam that is peaked in the center and deliver the desired uniform or nonuniform dose distribution. Removing the flattening filter could lead to reduced treatment time through higher dose rates and reduced scatter, because there would be substantially less material in the beam; and possibly other dosimetric and clinical advantages. This work aims to evaluate the properties of a flattening filter free clinical accelerator and to investigate its possible advantages in clinical intensity modulated radiation therapy applications by simulating a Varian 2100-based treatment delivery system with Monte Carlo techniques. Several depth-dose curves and lateral dose distribution profiles have been created for various field sizes, with and without the flattening filter. Data computed with this model were used to evaluate the overall quality of such a system in terms of changes in dose rate, photon and electron fluence, and reduction in out-of-field stray dose from the scattered components and were compared to the corresponding data for a standard treatment head with a flattening filter. The results of the simulations of the flattening filter free system show that a substantial increase in dose rate can be achieved, which would reduce the beam on time and decrease the out-of-field dose for patients due to reduced head-leakage dose. Also close to the treatment field edge, a significant improvement in out-of-field dose could be observed for small fields, which can be attributed to the change in the photon spectra, when the flattening filter is removed from the beamline.</description><identifier>ISSN: 0094-2405</identifier><identifier>EISSN: 2473-4209</identifier><identifier>DOI: 10.1118/1.2198327</identifier><identifier>PMID: 16872067</identifier><identifier>CODEN: MPHYA6</identifier><language>eng</language><publisher>United States: American Association of Physicists in Medicine</publisher><subject>beam line modification ; COMPUTERIZED SIMULATION ; Copper ; DEPTH DOSE DISTRIBUTIONS ; DOSE RATES ; DOSIMETRY ; Dosimetry/exposure assessment ; Electron scattering ; Field size ; flattening filter free ; intensity modulation ; Ionization chambers ; LINEAR ACCELERATORS ; MONTE CARLO METHOD ; Monte Carlo methods ; Monte Carlo simulations ; PATIENTS ; Photon scattering ; PHOTONS ; RADIATION DOSES ; Radiation sources ; radiation therapy ; Radiation treatment ; RADIOLOGY AND NUCLEAR MEDICINE ; RADIOTHERAPY ; Surface ionization ; treatment head modification ; Treatment strategy ; Wedges and compensators</subject><ispartof>Medical physics (Lancaster), 2006-06, Vol.33 (6), p.1595-1602</ispartof><rights>American Association of Physicists in Medicine</rights><rights>2006 American Association of Physicists in Medicine</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3857-75189fec7d98644146a2a8e31d78479fd2e95e6df92e1c2c46e37539bb52f81e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1118%2F1.2198327$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1118%2F1.2198327$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,314,780,784,885,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16872067$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/20853175$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Titt, U.</creatorcontrib><creatorcontrib>Vassiliev, O. N.</creatorcontrib><creatorcontrib>Pönisch, F.</creatorcontrib><creatorcontrib>Dong, L.</creatorcontrib><creatorcontrib>Liu, H.</creatorcontrib><creatorcontrib>Mohan, R.</creatorcontrib><title>A flattening filter free photon treatment concept evaluation with Monte Carlo</title><title>Medical physics (Lancaster)</title><addtitle>Med Phys</addtitle><description>In principle, the concept of flat initial radiation-dose distribution across the beam is unnecessary for intensity modulated radiation therapy. Dynamic leaf positioning during irradiation could appropriately adjust the fluence distribution of an unflattened beam that is peaked in the center and deliver the desired uniform or nonuniform dose distribution. Removing the flattening filter could lead to reduced treatment time through higher dose rates and reduced scatter, because there would be substantially less material in the beam; and possibly other dosimetric and clinical advantages. This work aims to evaluate the properties of a flattening filter free clinical accelerator and to investigate its possible advantages in clinical intensity modulated radiation therapy applications by simulating a Varian 2100-based treatment delivery system with Monte Carlo techniques. Several depth-dose curves and lateral dose distribution profiles have been created for various field sizes, with and without the flattening filter. Data computed with this model were used to evaluate the overall quality of such a system in terms of changes in dose rate, photon and electron fluence, and reduction in out-of-field stray dose from the scattered components and were compared to the corresponding data for a standard treatment head with a flattening filter. The results of the simulations of the flattening filter free system show that a substantial increase in dose rate can be achieved, which would reduce the beam on time and decrease the out-of-field dose for patients due to reduced head-leakage dose. Also close to the treatment field edge, a significant improvement in out-of-field dose could be observed for small fields, which can be attributed to the change in the photon spectra, when the flattening filter is removed from the beamline.</description><subject>beam line modification</subject><subject>COMPUTERIZED SIMULATION</subject><subject>Copper</subject><subject>DEPTH DOSE DISTRIBUTIONS</subject><subject>DOSE RATES</subject><subject>DOSIMETRY</subject><subject>Dosimetry/exposure assessment</subject><subject>Electron scattering</subject><subject>Field size</subject><subject>flattening filter free</subject><subject>intensity modulation</subject><subject>Ionization chambers</subject><subject>LINEAR ACCELERATORS</subject><subject>MONTE CARLO METHOD</subject><subject>Monte Carlo methods</subject><subject>Monte Carlo simulations</subject><subject>PATIENTS</subject><subject>Photon scattering</subject><subject>PHOTONS</subject><subject>RADIATION DOSES</subject><subject>Radiation sources</subject><subject>radiation therapy</subject><subject>Radiation treatment</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>RADIOTHERAPY</subject><subject>Surface ionization</subject><subject>treatment head modification</subject><subject>Treatment strategy</subject><subject>Wedges and compensators</subject><issn>0094-2405</issn><issn>2473-4209</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><recordid>eNp90MtKI0EUBuBCRsYYXcwLSMHALITWul-WEsYLGHQxsy4q1adMDZ2utrui-PZ2TAbd6Oos_u8cDj9CPyg5o5Sac3rGqDWc6T00YULzSjBiv6EJIVZUTBB5gA6H4R8hRHFJvqMDqoxmROkJml_g2PhSoE3tA46pKdDj2APgbplLbnHpwZcVtAWH3AboCoYn36x9SWP4nMoSz3NbAM983-QjtB99M8Dxbk7R38vff2bX1e3d1c3s4rYK3EhdaUmNjRB0bY0SggrlmTfAaa2N0DbWDKwEVUfLgAYWhAKuJbeLhWTRUOBT9HN7Nw8luSGkAmE5_tdCKI4RIzkd_RT92qquz49rGIpbpSFA0_gW8npwyiittVQjPNnB9WIFtev6tPL9i_tf0wiqLXhODby858Rt-nfU7fp38_vNGP3p1m9ee6vq852v8FPuPxzv6shfASW2kVI</recordid><startdate>200606</startdate><enddate>200606</enddate><creator>Titt, U.</creator><creator>Vassiliev, O. N.</creator><creator>Pönisch, F.</creator><creator>Dong, L.</creator><creator>Liu, H.</creator><creator>Mohan, R.</creator><general>American Association of Physicists in Medicine</general><scope>NPM</scope><scope>7X8</scope><scope>OTOTI</scope></search><sort><creationdate>200606</creationdate><title>A flattening filter free photon treatment concept evaluation with Monte Carlo</title><author>Titt, U. ; Vassiliev, O. N. ; Pönisch, F. ; Dong, L. ; Liu, H. ; Mohan, R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3857-75189fec7d98644146a2a8e31d78479fd2e95e6df92e1c2c46e37539bb52f81e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>beam line modification</topic><topic>COMPUTERIZED SIMULATION</topic><topic>Copper</topic><topic>DEPTH DOSE DISTRIBUTIONS</topic><topic>DOSE RATES</topic><topic>DOSIMETRY</topic><topic>Dosimetry/exposure assessment</topic><topic>Electron scattering</topic><topic>Field size</topic><topic>flattening filter free</topic><topic>intensity modulation</topic><topic>Ionization chambers</topic><topic>LINEAR ACCELERATORS</topic><topic>MONTE CARLO METHOD</topic><topic>Monte Carlo methods</topic><topic>Monte Carlo simulations</topic><topic>PATIENTS</topic><topic>Photon scattering</topic><topic>PHOTONS</topic><topic>RADIATION DOSES</topic><topic>Radiation sources</topic><topic>radiation therapy</topic><topic>Radiation treatment</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>RADIOTHERAPY</topic><topic>Surface ionization</topic><topic>treatment head modification</topic><topic>Treatment strategy</topic><topic>Wedges and compensators</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Titt, U.</creatorcontrib><creatorcontrib>Vassiliev, O. N.</creatorcontrib><creatorcontrib>Pönisch, F.</creatorcontrib><creatorcontrib>Dong, L.</creatorcontrib><creatorcontrib>Liu, H.</creatorcontrib><creatorcontrib>Mohan, R.</creatorcontrib><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><jtitle>Medical physics (Lancaster)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Titt, U.</au><au>Vassiliev, O. N.</au><au>Pönisch, F.</au><au>Dong, L.</au><au>Liu, H.</au><au>Mohan, R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A flattening filter free photon treatment concept evaluation with Monte Carlo</atitle><jtitle>Medical physics (Lancaster)</jtitle><addtitle>Med Phys</addtitle><date>2006-06</date><risdate>2006</risdate><volume>33</volume><issue>6</issue><spage>1595</spage><epage>1602</epage><pages>1595-1602</pages><issn>0094-2405</issn><eissn>2473-4209</eissn><coden>MPHYA6</coden><abstract>In principle, the concept of flat initial radiation-dose distribution across the beam is unnecessary for intensity modulated radiation therapy. Dynamic leaf positioning during irradiation could appropriately adjust the fluence distribution of an unflattened beam that is peaked in the center and deliver the desired uniform or nonuniform dose distribution. Removing the flattening filter could lead to reduced treatment time through higher dose rates and reduced scatter, because there would be substantially less material in the beam; and possibly other dosimetric and clinical advantages. This work aims to evaluate the properties of a flattening filter free clinical accelerator and to investigate its possible advantages in clinical intensity modulated radiation therapy applications by simulating a Varian 2100-based treatment delivery system with Monte Carlo techniques. Several depth-dose curves and lateral dose distribution profiles have been created for various field sizes, with and without the flattening filter. Data computed with this model were used to evaluate the overall quality of such a system in terms of changes in dose rate, photon and electron fluence, and reduction in out-of-field stray dose from the scattered components and were compared to the corresponding data for a standard treatment head with a flattening filter. The results of the simulations of the flattening filter free system show that a substantial increase in dose rate can be achieved, which would reduce the beam on time and decrease the out-of-field dose for patients due to reduced head-leakage dose. Also close to the treatment field edge, a significant improvement in out-of-field dose could be observed for small fields, which can be attributed to the change in the photon spectra, when the flattening filter is removed from the beamline.</abstract><cop>United States</cop><pub>American Association of Physicists in Medicine</pub><pmid>16872067</pmid><doi>10.1118/1.2198327</doi><tpages>8</tpages></addata></record> |
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subjects | beam line modification COMPUTERIZED SIMULATION Copper DEPTH DOSE DISTRIBUTIONS DOSE RATES DOSIMETRY Dosimetry/exposure assessment Electron scattering Field size flattening filter free intensity modulation Ionization chambers LINEAR ACCELERATORS MONTE CARLO METHOD Monte Carlo methods Monte Carlo simulations PATIENTS Photon scattering PHOTONS RADIATION DOSES Radiation sources radiation therapy Radiation treatment RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY Surface ionization treatment head modification Treatment strategy Wedges and compensators |
title | A flattening filter free photon treatment concept evaluation with Monte Carlo |
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