A simple approach for detecting HLA‐A02 alleles in archival formalin‐fixed paraffin‐embedded tissue samples and an application example for studying cancer immunoediting

The HLA system represents a central component of the antigen presentation machinery. As every patient possesses a defined set of HLA molecules, only certain antigens can be presented on the cell surface. Thus, studying HLA type‐dependent antigen presentation can improve the understanding of variatio...

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Veröffentlicht in:	HLA 2023-01, Vol.101 (1), p.24-33
Hauptverfasser:	Witt, Johannes, Haupt, Saskia, Ahadova, Aysel, Bohaumilitzky, Lena, Fuchs, Vera, Ballhausen, Alexej, Przybilla, Moritz Jakob, Jendrusch, Michael, Seppälä, Toni T., Fürst, Daniel, Walle, Thomas, Busch, Elena, Haag, Georg Martin, Hüneburg, Robert, Nattermann, Jacob, Knebel Doeberitz, Magnus, Heuveline, Vincent, Kloor, Matthias
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles cancer immunoediting DNA formalin‐fixed paraffin‐embedded tissue samples HLA typing HLA-A Antigens - genetics Humans MSI cancer Neoplasms - diagnosis Neoplasms - genetics
Online-Zugang:	Volltext
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