Amyotrophic lateral sclerosis with speech apraxia, predominant upper motor neuron signs, and prominent iron accumulation in the frontal operculum and precentral gyrus

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease; transactivation response DNA‐binding protein of 43 kDa (TDP‐43) and iron accumulation are supposed to play a crucial role in the pathomechanism of the disease. Here, we report an unusual case of a patient with ALS who pr...

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